Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Miranda A. Paley"'
Autor:
Miranda A. Paley
Publikováno v:
ACS Central Science, Vol 3, Iss 1, Pp 1-2 (2017)
Externí odkaz:
https://doaj.org/article/19326c30543247bd8d1203974ca7cff1
Autor:
Carolyn R. Bertozzi, Miranda A. Paley
Publikováno v:
ACS Central Science, Vol 2, Iss 12, Pp 872-873 (2016)
Externí odkaz:
https://doaj.org/article/6de22c001eca4d89a1587d43042b10bb
Autor:
Carolyn R. Bertozzi, Miranda A. Paley
Publikováno v:
ACS Central Science, Vol 1, Iss 5, Pp 217-218 (2015)
Externí odkaz:
https://doaj.org/article/132453914865413db95ffad49e09a5c2
Autor:
Krysten A. Jones, William B. Porterfield, Colin M. Rathbun, Jennifer A. Prescher, David C. McCutcheon, Miranda A. Paley
Publikováno v:
Journal of the American Chemical Society. 139:2351-2358
Bioluminescence imaging with luciferase-luciferin pairs is widely used in biomedical research. Several luciferases have been identified in nature, and many have been adapted for tracking cells in whole animals. Unfortunately, the optimal luciferases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8800f8b0a062c582f32929b15d953a09
https://doi.org/10.1021/jacs.6b11737
https://doi.org/10.1021/jacs.6b11737
Autor:
Jennifer A. Prescher, Rachel C. Steinhardt, Miranda A. Paley, David C. McCutcheon, Colin M. Rathbun, Jessica M. O'Neill
Publikováno v:
Steinhardt, RC; O'Neill, JM; Rathbun, CM; McCutcheon, DC; Paley, MA; & Prescher, JA. (2016). Design and Synthesis of an Alkynyl Luciferin Analogue for Bioluminescence Imaging.. Chemistry (Weinheim an der Bergstrasse, Germany), 22(11), 3671-3675. doi: 10.1002/chem.201503944. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1p06n749
Herein, the synthesis and characterization of an alkyne-modified luciferin is reported. This bioluminescent probe was accessed using C-H activation methodology and was found to be stable in solution and capable of light production with firefly lucife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95df91aa48cbece144194e0ef8664449
https://doi.org/10.1002/chem.201503944
https://doi.org/10.1002/chem.201503944
Autor:
Jennifer A. Prescher, Miranda A. Paley
Publikováno v:
MedChemComm, vol 5, iss 3
Bioluminescence is a ubiquitous imaging modality for visualizing biological processes in vivo. This technique employs visible light and interfaces readily with most cell and tissue types, making it a versatile technology for preclinical studies. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e0596467f5e98f976cc1fa6fce7b7b
https://doi.org/10.1039/c3md00288h
https://doi.org/10.1039/c3md00288h
Publikováno v:
Journal of the American Chemical Society. 134:7604-7607
Bioluminescence imaging with luciferase enzymes requires access to light-emitting, small-molecule luciferins. Here, we describe a rapid method to synthesize d-luciferin, the substrate for firefly luciferase (Fluc), along with a novel set of electroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90803a7a02107a6b03cbd01d1de6856
https://doi.org/10.1021/ja301493d
https://doi.org/10.1021/ja301493d
Autor:
J. Michael McIntosh, Miranda A. Paley, Charles R. Wageman, Outi Salminen, Paul Whiteaker, Sharon R. Grady, Michael J. Marks
Nicotinic acetylcholine receptors (nAChR) of the α6β2* subtype (where *indicates the possible presence of additional subunits) are prominently expressed on dopaminergic neurons. Because of this, their role in tobacco use and nicotine dependence has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d9bdc017ce30a79a87b8dd11f100e4
https://europepmc.org/articles/PMC4107044/
https://europepmc.org/articles/PMC4107044/
Autor:
Gadarla Randheer Reddy, Miranda A. Paley, Stephen C. Miller, Spencer T. Adams, Melanie S. Evans, Neil Aronin, Joanna P Chaurette, Jennifer A. Prescher
Publikováno v:
Evans, MS; Chaurette, JP; Adams, ST; Reddy, GR; Paley, MA; Aronin, N; et al.(2014). A synthetic luciferin improves bioluminescence imaging in live mice. Nature Methods, 11(4), 393-395. doi: 10.1038/nmeth.2839. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4424q4b3
Nature methods, vol 11, iss 4
Nature methods
Nature methods, vol 11, iss 4
Nature methods
Firefly luciferase is the most widely used optical reporter for noninvasive bioluminescence imaging (BLI) in rodents. BLI relies on the ability of the injected luciferase substrate D-luciferin to access luciferase-expressing cells and tissues within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fbf30407e70eccc9829e1e803854e5
http://www.escholarship.org/uc/item/4424q4b3
http://www.escholarship.org/uc/item/4424q4b3
Publikováno v:
ChemInform. 41
A wide variety of aldehydes, ketones, and lactols undergo redox amination when allowed to react with 3-pyrroline in the presence of a mild Bronsted acid catalyst. This reaction utilizes the inherent reducing power of 3-pyrroline to perform the equiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c02d6eb5fbdb7f690be1a839184343f
https://doi.org/10.1002/chin.201014101
https://doi.org/10.1002/chin.201014101