Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Miranda, Fischer"'
Autor:
Helen L Wu, Whitney C Weber, Courtney M Waytashek, Carla D Boyle, Jason S Reed, Katherine B Bateman, Hannah K Fisher, Yan Chen, Kimberly Armantrout, Tonya Swanson, Christine Shriver-Munsch, Mina Northrup, Miranda Fischer, Sreya Biswas, John Templon, Angela Panoskaltsis-Mortari, Benjamin J Burwitz, Amanda L Johnson, Lois Colgin, Anne D Lewis, Jeremy V Smedley, Michael K Axthelm, Rebecca Skalsky, Gabrielle Meyers, Richard T Maziarz, Erik Mittra, Melissa Berg, Jeffrey J Stanton, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 20, Iss 11, p e1012644 (2024)
Immunocompromised individuals are at risk for developing lymphocryptovirus-associated lymphoproliferative diseases, such as Epstein Barr virus (EBV)-associated B cell lymphomas and post-transplant lymphoproliferative disorder (PTLD). We previously re
Externí odkaz:
https://doaj.org/article/e9b7c4d3cacf41f4b7d8c3b2d116c58e
Autor:
Rachele M. Bochart, Kimberly Armantrout, Hugh Crank, Rachael Tonelli, Christine Shriver-Munsch, Tonya Swanson, Miranda Fischer, Helen Wu, Michael Axthelm, Jonah Sacha, Jeremy V. Smedley
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Methicillin-resistant Staphylococcus aureus (MRSA) is a S. aureus strain with resistance to beta-lactam antibiotics, making it a global human and veterinary health concern. Specifically, immunosuppressed patients have a remarkably higher risk of clin
Externí odkaz:
https://doaj.org/article/100d9e5d6af848b19bf6aa76a0f55030
Autor:
Nina Derby, Sreya Biswas, Sofiya Yusova, Cristina Luevano-Santos, Maria Cristina Pacheco, Kimberly A. Meyer, Brooke I. Johnson, Miranda Fischer, Katherine A. Fancher, Cole Fisher, Yohannes M. Abraham, Conor J. McMahon, Savannah S. Lutz, Jeremy V. Smedley, Benjamin J. Burwitz, Donald L. Sodora
Publikováno v:
Viruses, Vol 16, Iss 2, p 296 (2024)
Metabolic-dysfunction-associated fatty liver disease (MAFLD) is a major cause of morbidity and mortality in HIV-infected individuals, even those receiving optimal antiretroviral therapy. Here, we utilized the SIV rhesus macaque model and advanced lap
Externí odkaz:
https://doaj.org/article/cf243f8ab54e4cc8859bf12d3cd45809
Autor:
Sreya Biswas, Lauren N. Rust, Jochen M. Wettengel, Sofiya Yusova, Miranda Fischer, Julien N. Carson, Josie Johnson, Lei Wei, Trason Thode, Mohan R. Kaadige, Sunil Sharma, Majd Agbaria, Benjamin N. Bimber, Thomas Tu, Ulrike Protzer, Alexander Ploss, Jeremy V. Smedley, Gershon Golomb, Jonah B. Sacha, Benjamin J. Burwitz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Here, Biswas et al. present and characterize a second-generation model of HBV infection in rhesus macaques, showing that extended infection requires suppression of host immunity.
Externí odkaz:
https://doaj.org/article/6626a89b33b1442db7ec196681607c1f
Autor:
Xiao L. Chang, Gabriela M. Webb, Helen L. Wu, Justin M. Greene, Shaheed Abdulhaqq, Katherine B. Bateman, Jason S. Reed, Cleiton Pessoa, Whitney C. Weber, Nicholas Maier, Glen M. Chew, Roxanne M. Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M. Magnani, Jeremy Smedley, Benjamin N. Bimber, Nancy L. Haigwood, Scott G. Hansen, Timothy R. Brown, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
CCR5 is a co-receptor for many transmitted HIV strains. Here, the authors show that biweekly injection of the CCR5-specific antibody Leronlimab protects rhesus macaques against infection following repeated intrarectal challenges of a CCR5-tropic SHIV
Externí odkaz:
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
Autor:
Xiao L Chang, Jason S Reed, Gabriela M Webb, Helen L Wu, Jimmy Le, Katherine B Bateman, Justin M Greene, Cleiton Pessoa, Courtney Waytashek, Whitney C Weber, Joseph Hwang, Miranda Fischer, Cassandra Moats, Oriene Shiel, Rachele M Bochart, Hugh Crank, Don Siess, Travis Giobbi, Jeffrey Torgerson, Rebecca Agnor, Lina Gao, Kush Dhody, Jacob P Lalezari, Ivo Sah Bandar, Alnor M Carnate, Alina S Pang, Michael J Corley, Scott Kelly, Nader Pourhassan, Jeremy Smedley, Benjamin N Bimber, Scott G Hansen, Lishomwa C Ndhlovu, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010396 (2022)
The CCR5-specific antibody Leronlimab is being investigated as a novel immunotherapy that can suppress HIV replication with minimal side effects. Here we studied the virological and immunological consequences of Leronlimab in chronically CCR5-tropic
Externí odkaz:
https://doaj.org/article/e58ad860af654e17bfc075a249a3a48a
Autor:
Xiao L. Chang, Helen L. Wu, Gabriela M. Webb, Meenakshi Tiwary, Colette Hughes, Jason S. Reed, Joseph Hwang, Courtney Waytashek, Carla Boyle, Cleiton Pessoa, Andrew W. Sylwester, David Morrow, Karina Belica, Miranda Fischer, Scott Kelly, Nader Pourhassan, Rachele M. Bochart, Jeremy Smedley, Christopher P. Recknor, Scott G. Hansen, Jonah B. Sacha
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CCR5 plays a central role in infectious disease, host defense, and cancer progression, thereby making it an ideal target for therapeutic development. Notably, CCR5 is the major HIV entry co-receptor, where its surface density correlates with HIV plas
Externí odkaz:
https://doaj.org/article/90d1587b8e514b8db82121653a4bb63e
Autor:
Mariya B. Shapiro, Tracy Cheever, Delphine C. Malherbe, Shilpi Pandey, Jason Reed, Eun Sung Yang, Keyun Wang, Amarendra Pegu, Xuejun Chen, Don Siess, David Burke, Heidi Henderson, Rebecca Lewinsohn, Miranda Fischer, Jeffrey J. Stanton, Michael K. Axthelm, Christoph Kahl, Byung Park, Anne D. Lewis, Jonah B. Sacha, John R. Mascola, Ann J. Hessell, Nancy L. Haigwood
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Broadly neutralizing antibodies (bNAbs) are being evaluated for HIV post-exposure prophylaxis (PEP) in the setting of vertical transmission. Here, using a macaque model of perinatal SHIV infection, the authors show that PEP for infant macaques within
Externí odkaz:
https://doaj.org/article/96930173c51d4c149db6d9fcbe66090f
Autor:
Jeremy V. Smedley, Rachele M. Bochart, Miranda Fischer, Heidi Funderburgh, Vanessa Kelly, Hugh Crank, Kim Armantrout, Oriene Shiel, Mitchell Robertson‐LeVay, Nikki Sternberger, Brian Schmaling, Sheila Roberts, Vicki Sekiguchi, Michael Reusz, Tiah Schwartz, Kimberly A. Meyer, Gabriela Webb, Roxanne M. Gilbride, Nicholas Dambrauskas, Daniela Andrade, Matthew Wood, Caralyn Labriola, Michael Axthelm, Nina Derby, Ben Varco‐Merth, Yoshinori Fukazawa, Scott Hansen, Jonah B. Sacha, Donald L. Sodora, D. Noah Sather
Publikováno v:
Journal of Medical Primatology. 51:270-277
Identification of lymph nodes (LNs) draining a specific site or in obese macaques can be challenging.Indocyanine Green (ICG) was administered intradermal (ID), intramuscular, in the oral mucosa, or subserosal in the colon followed by Near Infrared (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009e4afb85e7fc3e0b492d3131f52c98
https://doi.org/10.1111/jmp.12605
https://doi.org/10.1111/jmp.12605
Autor:
Bruce K. Patterson, Whitney C. Weber, Gabriela M. Webb, Katherine B. Bateman, Cleiton Pessoa, Shaheed A. Abdulhaqq, Lina Gao, Benjamin N. Bimber, Jonah B. Sacha, Scott G. Hansen, Xiao L. Chang, Justin M. Greene, Kush Dhody, Scott Kelly, Nancy L. Haigwood, Rebecca Agnor, Cassandra Moats, Glen M. Chew, Roxanne M. Gilbride, Jeremy Smedley, Nicole D Burnett, Oriene Shiel, Nicholas Maier, Don Siess, Lishomwa C. Ndhlovu, Miranda Fischer, Timothy R. Brown, Diogo M. Magnani, Jason S. Reed, Travis Giobbi, Jeffrey Torgerson, Helen L. Wu, Nader Pourhassan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
In the absence of a prophylactic vaccine, the use of antiretroviral therapy (ART) as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition by uninfected individuals is a promising approach to slowing the epidemic, but its efficacy is hampered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e606e6b89376a17f5abd25dc4b8683a
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7