Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Mirana, Ramialison"'
Autor:
Luana Nunes Santos, Ângela Maria Sousa Costa, Martin Nikolov, João E. Carvalho, Allysson Coelho Sampaio, Frank E. Stockdale, Gang Feng Wang, Hozana Andrade Castillo, Mariana Bortoletto Grizante, Stefanie Dudczig, Michelle Vasconcelos, Nadia Rosenthal, Patricia Regina Jusuf, Hieu T. Nim, Paulo de Oliveira, Tatiana Guimarães de Freitas Matos, William Nikovits, Izabella Luisa Tambones, Ana Carolina Migliorini Figueira, Michael Schubert, Mirana Ramialison, José Xavier-Neto
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Cardiac function requires appropriate proteins in each chamber. Atria requires slow myosin to act as reservoirs, while ventricles demand fast myosin for swift pumping. Myosins are thus under chamber-biased cis-regulation, with myosin gene ex
Externí odkaz:
https://doaj.org/article/ed3d633ab60a42d0b8e29591908da133
Autor:
Natalie Charitakis, Agus Salim, Adam T. Piers, Kevin I. Watt, Enzo R. Porrello, David A. Elliott, Mirana Ramialison
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Identifying spatially variable genes (SVGs) is a key step in the analysis of spatially resolved transcriptomics data. SVGs provide biological insights by defining transcriptomic differences within tissues, which was previously unachievable u
Externí odkaz:
https://doaj.org/article/1b4f8dd834724091bdaa2bce84d5993b
Autor:
Carmen de Sena-Tomás, Angelika G. Aleman, Caitlin Ford, Akriti Varshney, Di Yao, Jamie K. Harrington, Leonor Saúde, Mirana Ramialison, Kimara L. Targoff
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Cardiac developmental genes have been associated with regenerative potential. Here the authors identify a Nkx2.5-dependent gene regulatory network operating through ect2, psmb3, and psmd7 to orchestrate cell cycle re-entry, proteolysis, and mitochond
Externí odkaz:
https://doaj.org/article/af0afecefd024f31b89b53cbca457520
Autor:
Ziyin Xin, Yujun Cai, Louis T. Dang, Hannah M. S. Burke, Jerico Revote, Natalie Charitakis, Denis Bienroth, Hieu T. Nim, Yuan-Fang Li, Mirana Ramialison
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Gene ontology (GO) enrichment analysis is frequently undertaken during exploration of various -omics data sets. Despite the wide array of tools available to biologists to perform this analysis, meaningful visualisation of the over
Externí odkaz:
https://doaj.org/article/8739798a1ad5411a83830f52ed6d44a8
Autor:
Denis Bienroth, Hieu T. Nim, Dimitar Garkov, Karsten Klein, Sabrina Jaeger-Honz, Mirana Ramialison, Falk Schreiber
Publikováno v:
Visual Computing for Industry, Biomedicine, and Art, Vol 5, Iss 1, Pp 1-13 (2022)
Abstract Spatially resolved transcriptomics is an emerging class of high-throughput technologies that enable biologists to systematically investigate the expression of genes along with spatial information. Upon data acquisition, one major hurdle is t
Externí odkaz:
https://doaj.org/article/017e5ea75e9347368e2ec19752d2bed3
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Transcriptional regulation is primarily mediated by the binding of factors to non-coding regions in DNA. Identification of these binding regions enhances understanding of tissue formation and potentially facilitates the developmen
Externí odkaz:
https://doaj.org/article/98c10a2ce4f84c268d60a0af3aafcf79
Autor:
Hieu T. Nim, Louis Dang, Harshini Thiyagarajah, Daniel Bakopoulos, Michael See, Natalie Charitakis, Tennille Sibbritt, Michael P. Eichenlaub, Stuart K. Archer, Nicolas Fossat, Richard E. Burke, Patrick P. L. Tam, Coral G. Warr, Travis K. Johnson, Mirana Ramialison
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background Congenital heart diseases are the major cause of death in newborns, but the genetic etiology of this developmental disorder is not fully known. The conventional approach to identify the disease-causing genes focuses on screening g
Externí odkaz:
https://doaj.org/article/b9ab3ed0c9654b1f902b20578e0de93f
Publikováno v:
Heliyon, Vol 8, Iss 10, Pp e11093- (2022)
Acute myeloid leukemia (AML) is one of the most prevalent and acute blood cancers with a poor prognosis and low overall survival rate, especially in the elderly. Although several new AML markers and drug targets have been recently identified, the rat
Externí odkaz:
https://doaj.org/article/bed663c6c63d4e1f8845f868f2c24ad2
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108099- (2022)
The transcriptional response to cellular stress relies upon trafficking of regulators of transcription between the nuclear and cytoplasmic compartments, which occurs through action of members of the importin (IPO) superfamily. As a result of stresses
Externí odkaz:
https://doaj.org/article/b28b2971f773457fbc70f12892a534e8
Autor:
Shicheng Sun, Jacky Y. Li, Hieu T. Nim, Adam Piers, Mirana Ramialison, Enzo R. Porrello, Igor E. Konstantinov, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Thymic epithelium is critical for the structural integrity of the thymus and for T cell development. Within the fully formed thymus, large numbers of hematopoietic cells shape the thymic epithelium into a scaffold-like structure which bears little si
Externí odkaz:
https://doaj.org/article/78af4cce953b45bf916d16eb982f3b10