Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Miran Yoon-Robarts"'
Autor:
Jorge Mansilla-Soto, Miran Yoon-Robarts, William J Rice, Shailee Arya, Carlos R Escalante, R Michael Linden
Publikováno v:
PLoS Pathogens, Vol 5, Iss 7, p e1000513 (2009)
Rep68 is a multifunctional protein of the adeno-associated virus (AAV), a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific in
Externí odkaz:
https://doaj.org/article/113c6e3818ce4a148e9456a05bcb1f14
Autor:
Jürgen A. Kleinschmidt, Amanda G. Blouin, Svenja Bleker, R. Michael Linden, Aneel K. Aggarwal, Carlos R. Escalante, Miran Yoon-Robarts
Publikováno v:
Journal of Biological Chemistry. 279:50472-50481
We have recently published the crystal structure of the adeno-associated virus type 2 superfamily 3 (SF3) helicase Rep40. Although based on its biochemical properties it is unlikely that Rep40 plays a central role as a replicative helicase the involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2be1b9a00fe9c1badf4ab59e860052
https://doi.org/10.1074/jbc.m403900200
https://doi.org/10.1074/jbc.m403900200
Autor:
William J. Rice, Miran Yoon-Robarts, R. Michael Linden, Carlos R. Escalante, Shailee Arya, Jorge Mansilla-Soto
Publikováno v:
PLoS Pathogens, Vol 5, Iss 7, p e1000513 (2009)
PLoS Pathogens
PLoS Pathogens
Rep68 is a multifunctional protein of the adeno-associated virus (AAV), a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30aa8d3902177fda1ff4aad47c6a90a
http://europepmc.org/articles/PMC2702170?pdf=render
http://europepmc.org/articles/PMC2702170?pdf=render
Autor:
Els Henckaerts, Nathalie Dutheil, R. Michael Linden, Lucy Skrabanek, Kenneth I. Berns, Miran Yoon-Robarts, Pete Ward, Fabien Campagne
The nonpathogenic human adeno-associated virus (AAV) has developed a mechanism to integrate its genome into human chromosome 19 at 19q13.4 (termed AAVS1 ), thereby establishing latency. Here, we provide evidence that the chromosomal signals required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcba750d787207d37cf98cc6f56040b
https://lirias.kuleuven.be/handle/123456789/677232
https://lirias.kuleuven.be/handle/123456789/677232
Autor:
Miran Yoon-Robarts, R. Michael Linden, Aneel K. Aggarwal, Thomas A. Edwards, Carlos R. Escalante, J. Anson James
Publikováno v:
Structure (London, England : 1993). 11(8)
We report here the crystal structure of an SF3 DNA helicase, Rep40, from adeno-associated virus 2 (AAV2). We show that AAV2 Rep40 is structurally more similar to the AAA + class of cellular proteins than to DNA helicases from other superfamilies. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7c51fef0ea6519a3c3b8c077534251
https://pubmed.ncbi.nlm.nih.gov/12906833
https://pubmed.ncbi.nlm.nih.gov/12906833
Autor:
R. Michael Linden, Miran Yoon-Robarts
Publikováno v:
The Journal of biological chemistry. 278(7)
Adeno-associated virus type 2 Rep endonuclease activity is necessary for both viral DNA replication and site-specific integration of the viral genome into human chromosome 19. The biochemical activities required for site-specific endonuclease activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b7ccb747b126f3b4dc1da6b4370f7a
https://pubmed.ncbi.nlm.nih.gov/12480938
https://pubmed.ncbi.nlm.nih.gov/12480938