Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mira Valcic"'
Autor:
Arnold Melman, George J. Christ, Kelvin P. Davies, Mira Valcic, Moses Tar, Jason D. Hipp, Abraham Knoll
Publikováno v:
BJU International. 99:418-430
OBJECTIVE To identify early diabetes-related alterations in gene expression in bladder and erectile tissue that would provide novel diagnostic and therapeutic treatment targets to prevent, delay or ameliorate the ensuing bladder and erectile dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778645026219af6d61810fe2872e54f8
https://doi.org/10.1111/j.1464-410x.2007.06676.x
https://doi.org/10.1111/j.1464-410x.2007.06676.x
Autor:
K. Hsieh, Cristian Santizo, J. Zinman, Michele E. Day, George J. Christ, K. Venkateswarlu, N. S. Day, Mira Valcic, A. Melman, Theresa Sclafani, Weixin Zhao
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 281:R1699-R1709
The goal of these studies was to examine the potential utility of bladder instilled K+channel gene therapy with hSlo cDNA (i.e., the maxi-K channel) to ameliorate bladder overactivity in a rat model of partial urinary outlet obstruction. Twenty-two f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c36c298b07bad29162db42727c3e8d9
https://doi.org/10.1152/ajpregu.2001.281.5.r1699
https://doi.org/10.1152/ajpregu.2001.281.5.r1699
Publikováno v:
Brain Research. 821:414-425
Modulation of the sexual behavior of male rats by the anxiolytic buspirone (S-20499) and its analog gepirone were compared to the effects of 8-OH-DPAT (or DPAT, a selective 5-HT1A reference agonist), and BMY-7378 (a selective 5-HT1A partial agonist).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded32607d8efe467590fb462e137d116
https://doi.org/10.1016/s0006-8993(98)01129-9
https://doi.org/10.1016/s0006-8993(98)01129-9
Autor:
Mariya Spektor, Mira Valcic, Herbert B. Tanowitz, Weixin Zhao, Stephen A. Douglas, Stephen A. Morris, Murray Wittner, George J. Christ, Louis M. Weiss, Victor B. Hatcher, Huan Huang, Vicki L. Braunstein
Publikováno v:
Endothelium. 6:217-230
Chagas' disease, caused by Trypanosoma cruzi, is an important cause of heart disease in Latin America. T. cruzi-induced microvascular compromise, in turn, is thought to play a major role in chagasic heart disease. Previous in vitro studies have impli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6fa0189b42980b878adfe5790393a4
https://doi.org/10.3109/10623329909053412
https://doi.org/10.3109/10623329909053412
Autor:
N. S. Day, Arnold Melman, Lawrence Salkoff, George J. Christ, Jamil Rehman, Jan Geliebter, Mira Valcic
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 275:H600-H608
The Ca2+-sensitive K+channel (maxi-K+) is an important modulator of corporal smooth muscle tone. The goal of these studies was twofold: 1) to determine the feasibility of transfecting corporal smooth muscle cells in vivo with the hSlo cDNA, which enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d9a590495334fc7457ef47f94df9e7
https://doi.org/10.1152/ajpheart.1998.275.2.h600
https://doi.org/10.1152/ajpheart.1998.275.2.h600
Publikováno v:
Journal of Urology. 155:1789-1794
To evaluate the utility of forskolin as a potentially novel intracavernous therapy.Forskolin- and prostaglandin E1 (PGE1)-induced intracorporal pressure changes were evaluated in vivo by cavernosometry performed on 2 male mongrel dogs, while systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a76795c81ac94e5e26269efd535497
https://doi.org/10.1016/s0022-5347(01)66199-8
https://doi.org/10.1016/s0022-5347(01)66199-8
Publikováno v:
Journal of Urology. 152:1308-1314
Intracavernous pharmacotherapy relies heavily on the use of vasoactive agents which act by increasing intracellular cAMP levels in human corpus cavernosum smooth muscle. Yet little is known about the cAMP generating system in this tissue, and how it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5bb455cb3ec6d2b54b948fc493d4d7
https://doi.org/10.1016/s0022-5347(17)32573-9
https://doi.org/10.1016/s0022-5347(17)32573-9
Publikováno v:
Life Sciences. 55:807-814
Kinetic studies were conducted on the contractile response elicited by phenylephrine (PE) and 5-hydroxytryptamine (5-HT) activation of the α 1 -adrenergic- and 5-HT 2 receptor subtypes, respectively, in aortic rings isolated from streptozotocin (STZ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5326351b153e84851c08118f5506aba
https://doi.org/10.1016/0024-3205(94)00564-8
https://doi.org/10.1016/0024-3205(94)00564-8
Autor:
Arnold Melman, George J. Christ, C. B. Schwartz, B. A. Stone, Marjorie Gondré, M. Parker, M. Janis, Mira Valcic
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 263:H15-H19
Kinetic studies were conducted on the contractile response elicited by phenylephrine (PE) activation of the alpha 1-adrenergic receptor subtype in vascular smooth muscle isolated from the corpus cavernosum of impotent men. PE-induced contractions wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b3c386cc6c0720cb79734dde11806f
https://doi.org/10.1152/ajpheart.1992.263.1.h15
https://doi.org/10.1152/ajpheart.1992.263.1.h15
Autor:
Arnold Melman, C.Marjorie Gondre, George J. Christ, Mira Valcic, A. P. Moreno, Melanie E. Parker, David C. Spray
Publikováno v:
Life Sciences. 49:PL195-PL200
Kinetic and steady-state protocols were used to examine the effects of disruption of intercellular communication with heptanol, on contractile responses elicited by activation of the alpha 1-adrenergic receptor in human corporal vascular smooth muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5d38b6693eff46bae67edb18eebad6
https://doi.org/10.1016/0024-3205(91)90489-x
https://doi.org/10.1016/0024-3205(91)90489-x