Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mira S Chaurushiya"'
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002084 (2011)
Cellular restriction factors responding to herpesvirus infection include the ND10 components PML, Sp100 and hDaxx. During the initial stages of HSV-1 infection, novel sub-nuclear structures containing these ND10 proteins form in association with inco
Externí odkaz:
https://doaj.org/article/412315e83fb548c8a9c7e34dd3cd5c76
Autor:
Sara Chan, Eric Stawiski, Christopher Tran, Mira S. Chaurushiya, Wyne P. Lee, Anwesha Dey, Boris C. Bastian, Xiumin Wu, Kathy Hötzel, Trang H. Pham, Klara Totpal, Sreedevi Chalasani, Ho-June Lee, Mengshu Xu, Jeffrey Hung, Zora Modrusan, Nicolas W. Hughes, Vishva M. Dixit, Eric Talevich, Neeraj Sharma, Matthew T. Chang, Alan Hunter Shain, Philamer C. Calses, Jennie R. Lill, Joshua D. Webster, Zhongwu Li
Publikováno v:
Pigment Cell & Melanoma Research. 32:269-279
The deubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with a high risk of mesothelioma and melanocytic tumors. Here, we show that Bap1 deletion in melanocytes cooperates with the constitutively active, oncogenic form of BRAF (BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff71ccb0cd9b433785d8061a603387b
https://doi.org/10.1111/pcmr.12735
https://doi.org/10.1111/pcmr.12735
Autor:
Rohit Reja, Roger Caothien, Ying-Jiun Chen, Benjamin Haley, Zora Modrusan, Subhra Chaudhuri, Meng He, Shari Lau, Merone Roose-Girma, Jeffrey Eastham-Anderson, Anwesha Dey, Mira S. Chaurushiya, Vishva M. Dixit, Sarah K. Kummerfeld, Debra L. Dugger, Joshua D. Webster, Kim Newton
Publikováno v:
Translational Cancer Research
Tissue specificity of tumor suppression It is well known that the loss of tumor suppressor genes leads to a limited subset of cancers in specific tissues. But why just those tissues? He et al. found a relatively simple explanation for how this tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4363a7cb53b12b54c6131b7a0388028
https://doi.org/10.1126/science.aav4902
https://doi.org/10.1126/science.aav4902
Autor:
Guillermo Garcia-Manero, Mercedesz Balazs, Flavius Martin, Sarah G. Hymowitz, Jiansheng Wu, Somasekar Seshagiri, Ken C. Dong, Mira S. Chaurushiya, Jinfeng Liu, Ross L. Levine, Vishva M. Dixit, Jennie R. Lill, Victoria Pham, Anwesha Dey, Omar Abdel-Wahab, Donald S. Kirkpatrick, Paula Katavolos, Rajkumar Noubade, Zhonghua Lin, Corey E. Bakalarski, Kim Newton, Rowena Suriben, Zora Modrusan, Dhaya Seshasayee, Lindsay M. LaFave, Lilian Phu, Dorothy French
Publikováno v:
Science (New York, N.Y.). 337(6101)
Identifying BAP1 Targets Inactivating mutations in the deubiquitinating enzyme BAP1 have been associated with cancer. Dey et al. (p. 1541 , published online 9 August; see the Perspective by White and Harper ) reveal molecular targets of the enzyme an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fa6ab258df855f8da74df9d4b349e4
https://pubmed.ncbi.nlm.nih.gov/22997315
https://pubmed.ncbi.nlm.nih.gov/22997315
Autor:
Matthew D. Weitzman, Caroline E. Lilley, Roger D. Everett, Chris Boutell, Mira S. Chaurushiya
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002084 (2011)
PLoS Pathogens
PLoS Pathogens
Cellular restriction factors responding to herpesvirus infection include the ND10 components PML, Sp100 and hDaxx. During the initial stages of HSV-1 infection, novel sub-nuclear structures containing these ND10 proteins form in association with inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a128bc006fb53a0a7e32ff4a6019d0
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21698222/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21698222/pdf/?tool=EBI
Viruses often induce signaling through the same cellular cascades that are activated by damage to the cellular genome. Signaling triggered by viral proteins or exogenous DNA delivered by viruses can be beneficial or detrimental to viral infection. Vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c925cea14d921a5ecce9f4ea88f51dab
https://europepmc.org/articles/PMC3312807/
https://europepmc.org/articles/PMC3312807/
Publikováno v:
Annual review of microbiology. 64
The cellular surveillance network for sensing and repairing damaged DNA prevents an array of human diseases, and when compromised it can lead to genomic instability and cancer. The carefully maintained cellular response to DNA damage is challenged du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a79aa393c47564d840ea2f80f0a99a
https://pubmed.ncbi.nlm.nih.gov/20690823
https://pubmed.ncbi.nlm.nih.gov/20690823
A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses
Autor:
Roger D. Everett, Sébastien Landry, Junghae Suh, Daniel Durocher, Matthew D. Weitzman, Chris Boutell, Grant S. Stewart, Stephanie Panier, Mira S. Chaurushiya, Caroline E. Lilley
Publikováno v:
EMBO J
The ICP0 protein of herpes simplex virus type 1 is an E3 ubiquitin ligase and transactivator required for the efficient switch between latent and lytic infection. As DNA damaging treatments are known to reactivate latent virus, we wished to explore w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c26c2b943775a3c799920945e1f023a
https://hdl.handle.net/21.11116/0000-000B-817C-8
https://hdl.handle.net/21.11116/0000-000B-817C-8
Publikováno v:
DNA repair. 8(9)
Recognition and repair of DNA damage is critical for maintaining genomic integrity and suppressing tumorigenesis. In eukaryotic cells, the sensing and repair of DNA damage are exquisitely coordinated with cell cycle progression and checkpoints, in or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d112421a06a67f957de7c6993325fb3c
https://pubmed.ncbi.nlm.nih.gov/19473887
https://pubmed.ncbi.nlm.nih.gov/19473887
Publikováno v:
Biochimica et biophysica acta. 1799(3-4)
During infection, viruses cause global disruption to nuclear architecture in their attempt to take over the cell. In turn, the host responds with various defenses, which include chromatin-mediated silencing of the viral genome and activation of DNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4925e3cae6d886d309a6e74eb1c02332
https://pubmed.ncbi.nlm.nih.gov/19616655
https://pubmed.ncbi.nlm.nih.gov/19616655