Výsledky vyhledávání - "Mira Grättinger"

Akademický článek

Characterization of ACE Inhibitors and AT1R Antagonists with Regard to Their Effect on ACE2 Expression and Infection with SARS-CoV-2 Using a Caco-2 Cell Model

Autor: Philipp Reus, Ann-Kathrin Schneider, Thomas Ulshöfer, Marina Henke, Denisa Bojkova, Jindrich Cinatl, Sandra Ciesek, Gerd Geisslinger, Volker Laux, Mira Grättinger, Philip Gribbon, Susanne Schiffmann

Publikováno v: Life, Vol 11, Iss 8, p 810 (2021)

Blood-pressure-lowering drugs are proposed to foster SARS-CoV-2 infection by pharmacological upregulation of angiotensin-converting enzyme 2 (ACE2), the binding partner of the virus spike (S) protein, located on the surface of the host cells. Convers

Externí odkaz: https://doaj.org/article/1523ec8abafc4b51b0d1e6cb3537030f

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Characterization of ACE Inhibitors and AT1R Antagonists with Regard to Their Effect on ACE2 Expression and Infection with SARS-CoV-2 Using a Caco-2 Cell Model

Autor: Susanne Schiffmann, Gerd Geisslinger, Philipp Reus, Philip Gribbon, Marina Henke, Sandra Ciesek, Volker Laux, Thomas Ulshöfer, Jindrich Cinatl, Denisa Bojkova, Ann-Kathrin Schneider, Mira Grättinger

Publikováno v: Life
Life, Vol 11, Iss 810, p 810 (2021)
Volume 11
Issue 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4083a4bb724ac9eb9cc2cc31bad353ce
http://europepmc.org/articles/PMC8399150

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AKT1 and PTEN show the highest affinities among phosphoinositide binding proteins for the second messengers PtdIns(3,4,5)P

Autor: Nina, Nelson, Adelia, Razeto, Alessia, Gilardi, Mira, Grättinger, Johannes, Kirchmair, Manfred, Jücker

Publikováno v: Biochemical and biophysical research communications. 568

The phosphoinositides phosphatidylinositol-3,4,5-trisphosphate [PtdIns(3,4,5)P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8c1f515d1ac84f7f82a00f76846611d
https://pubmed.ncbi.nlm.nih.gov/34214875

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AKT1 and PTEN show the highest affinities among phosphoinositide binding proteins for the second messengers PtdIns(3,4,5)P3 and PtdIns(3,4)P2

Autor: Adelia Razeto, Mira Grättinger, Johannes Kirchmair, Manfred Jücker, Alessia Gilardi, Nina Nelson

The phosphoinositides phosphatidylinositol-3,4,5-trisphosphate [PtdIns(3,4,5)P3] and phosphatidylinositol-3,4-bisphosphate [PtdIns(3,4)P2] function as second messengers and have been implicated in cancerogenesis. The signalling events downstream of P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec0570407209a3b776358530463785b
https://publica.fraunhofer.de/handle/publica/270045

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In VitroAssembly Properties of Wild-Type and Cyclophilin-Binding Defective Human Immunodeficiency Virus Capsid Proteins in the Presence and Absence of Cyclophilin A

Autor: Hans-Georg Kräusslich, Mira Grättinger, Dennis Thomas, Heinz Hohenberg, Barbara Müller, Thomas Wilk

Publikováno v: Virology. 257:247-260

The cellular protein cyclophilin A (CypA) binds specifically to the human immunodeficiency virus type 1 (HIV-1) capsid (CA) protein and is incorporated into HIV-1 particles at a molar ratio of 1:10 (CypA/CA). Structural analysis of a CA–CypA comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ec1a51e5557ef54f04a931617a5c6e
https://doi.org/10.1006/viro.1999.9668

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Recombinant phosphoglycerate kinase from the hyperthermophilic bacterium Thermotoga maritima : catalytic, spectral and thermodynamic properties 1 1Edited by R. Huber

Autor: Arnd Dankesreiter, Mira Grättinger, Hartmut Schurig, Rainer Jaenicke

Publikováno v: Journal of Molecular Biology. 280:525-533

Recombinant phosphoglycerate kinase from the hyperthermophilic bacterium Thermotoga maritima (TmPGK) has been expressed in Escherichia coli. The recombinant enzyme was purified to homogeneity applying heat incubation of the crude extract at 80 degree

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::111eef899c3f5ec14b9583279417b204
https://doi.org/10.1006/jmbi.1998.1861

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Closed structure of phosphoglycerate kinase from Thermotoga maritima reveals the catalytic mechanism and determinants of thermal stability

Autor: Uwe Jacob, Günter Auerbach, Robert Huber, Rainer Jaenicke, Mira Grättinger, Hartmut Schurig, Katrin Zaiss

Publikováno v: Structure. 5(11):1475-1483

Background: Phosphoglycerate kinase (PGK) is essential in most living cells both for ATP generation in the glycolytic pathway of aerobes and for fermentation in anaerobes. In addition, in many plants the enzyme is involved in carbon fixation. Like ot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857f19ec3c7d9fb9af93c1447b91bc2c

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Cyclophilin A incorporation is not required for human immunodeficiency virus type 1 particle maturation and does not destabilize the mature capsid

Autor: Mira Grättinger, Klaus Wiegers, Hans-Georg Kräusslich, Ulrich Schubert, Gabriel Rutter

Publikováno v: Virology. 257(1)

The cellular protein cyclophilin A (CypA) is packaged into human immunodeficiency virus type 1 (HIV-1) virions through a specific interaction with the capsid (CA) domain of the Gag polyprotein. CypA is important for infectivity, but its role in viral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def5eabbcd9252eb4d18c7cd18d3ea7e
https://pubmed.ncbi.nlm.nih.gov/10208939

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