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pro vyhledávání: '"Mira C P Liu"'
Autor:
Jaclyn Sceneay, Mira C P Liu, Anna Chen, Christina S F Wong, David D L Bowtell, Andreas Möller
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66388 (2013)
Intratumoral hypoxia is a poor prognostic factor associated with reduced disease-free survival in many cancer types, including breast cancer. Hypoxia encourages tumor cell proliferation, stimulates angiogenesis and lymphangiogenesis, and promotes epi
Externí odkaz:
https://doaj.org/article/b5d395d283a44cc7adcf19d61e0fc91d
Autor:
James N, Musyoka, Mira C P, Liu, Dodie S, Pouniotis, Christina S F, Wong, David D, Bowtell, Peter J, Little, Robel, Getachew, Andreas, Möller, Ian A, Darby
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 21(3)
Hypoxia is associated with the dermal wound healing process and hypoxia signaling is presumed to be crucial for normal wound repair. The Siah2 ubiquitin ligase controls the abundance of hypoxia-inducible factor-1 alpha, and loss of Siah2 results in d
Publikováno v:
Breast Cancer Research
Background Gene promoter methylation is an important regulator of expression and is a key epigenetic factor in tumorigenesis. DNA methylation is mediated by DNA methyltransferases (DNMTs), of which three active forms have been identified: DNMT1, DNM3