Participation of ventricular trabeculae in neonatal cardiac regeneration leads to ectopic recruitment of Purkinje-like cells.

Autor: Boulgakoff L; Aix-Marseille Université, CNRS UMR 7288, Developmental Biology Institute of Marseille, Marseille, France., Sturny R; Aix-Marseille Université, CNRS UMR 7288, Developmental Biology Institute of Marseille, Marseille, France., Olejnickova V; Charles University, First Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic., Sedmera D; Charles University, First Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic., Kelly RG; Aix-Marseille Université, CNRS UMR 7288, Developmental Biology Institute of Marseille, Marseille, France., Miquerol L; Aix-Marseille Université, CNRS UMR 7288, Developmental Biology Institute of Marseille, Marseille, France. lucile.miquerol@univ-amu.fr.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2024 Sep; Vol. 3 (9), pp. 1140-1157. Date of Electronic Publication: 2024 Aug 28.

Transient formation of collaterals contributes to the restoration of the arterial tree during cardiac regeneration in neonatal mice.

Autor: Sturny R; Aix-Marseille Université, CNRS IBDM UMR7288, Marseille, France., Boulgakoff L; Aix-Marseille Université, CNRS IBDM UMR7288, Marseille, France., Kelly RG; Aix-Marseille Université, CNRS IBDM UMR7288, Marseille, France., Miquerol L; Aix-Marseille Université, CNRS IBDM UMR7288, Marseille, France.

Publikováno v: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2024 Oct; Vol. 195, pp. 1-13. Date of Electronic Publication: 2024 Jul 20.

Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells.

Autor: Fowler JL; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA., Zheng SL; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA., Nguyen A; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA., Chen A; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA., Xiong X; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA., Chai T; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA., Chen JY; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA., Karigane D; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Division of Hematology, Department of Medicine, Stanford University, Stanford, CA 94305, USA., Banuelos AM; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Niizuma K; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Kayamori K; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Division of Hematology, Department of Medicine, Stanford University, Stanford, CA 94305, USA., Nishimura T; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Cromer MK; Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA., Gonzalez-Perez D; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Mason C; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Liu DD; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Yilmaz L; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Miquerol L; Aix-Marseille Université, CNRS UMR 7288, IBDM, Marseille 13288, France., Porteus MH; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Pediatrics, Stanford University, Stanford, CA 94305, USA., Luca VC; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Majeti R; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Division of Hematology, Department of Medicine, Stanford University, Stanford, CA 94305, USA., Nakauchi H; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Red-Horse K; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA., Weissman IL; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Pathology, Stanford University, Stanford, CA 94305, USA., Ang LT; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address: layteng@stanford.edu., Loh KM; Institute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: kyleloh@stanford.edu.

Publikováno v: Developmental cell [Dev Cell] 2024 May 06; Vol. 59 (9), pp. 1110-1131.e22. Date of Electronic Publication: 2024 Apr 02.

Dbh ⁺ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart.

Autor: Sun T; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., Grassam-Rowe A; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., Pu Z; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Department of Cardiology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China., Li Y; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Department of Cardiology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China., Ren H; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Department of Physiology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, 646000, China., An Y; BGI Research, Shenzhen, 518103, China., Guo X; BGI Research, Qingdao, 266555, China., Hu W; Department of Physics & Astronomy, The University of Manchester, Brunswick Street, Manchester, M13 9PL, UK., Liu Y; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA., Zheng Y; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Department of Cardiology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China., Liu Z; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Department of Cardiology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China., Kou K; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Department of Cardiology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China., Ou X; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China., Chen T; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China., Fan X; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China., Liu Y; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA., Tu S; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., He Y; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., Ren Y; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., Chen A; BGI Research, Shenzhen, 518103, China., Shang Z; BGI Research, Shenzhen, 518103, China., Xia Z; Centre for Nanohealth, Swansea University Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, UK., Miquerol L; Aix Marseille University, CNRS Institut de Biologie du Développement de Marseille UMR 7288, 13288, Marseille, France., Smart N; Department of Physiology, Anatomy & Genetics, Sherrington Building, Oxford, University of, Oxford, OX1 3PT, UK., Zhang H; Department of Physics & Astronomy, The University of Manchester, Brunswick Street, Manchester, M13 9PL, UK.; Beijing Academy of Artificial Intelligence, 100084, Beijing, China., Tan X; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China. tanxiaoqiu@swmu.edu.cn.; Department of Cardiology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China. tanxiaoqiu@swmu.edu.cn.; Department of Physiology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, Sichuan, 646000, China. tanxiaoqiu@swmu.edu.cn., Shou W; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA. wshou@iu.edu., Lei M; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK. ming.lei@pharm.ox.ac.uk.; Key Laboratory of Medical Electrophysiology of the Ministry of Education, and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China. ming.lei@pharm.ox.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 28; Vol. 14 (1), pp. 7801. Date of Electronic Publication: 2023 Nov 28.

Nkx2-5 Loss of Function in the His-Purkinje System Hampers Its Maturation and Leads to Mechanical Dysfunction.

Autor: Choquet C; Aix-Marseille Univ, CNRS UMR 7288, IBDM, 13288 Marseille, France; Aix-Marseille Univ, INSERM, MMG, 13385 Marseille, France, Sicard P; INSERM, CNRS, Université de Montpellier, PHYMEDEXP, 34295 Montpellier, France, Vahdat J; Aix-Marseille Univ, CNRS UMR 7288, IBDM, 13288 Marseille, France, Nguyen THM; Aix-Marseille Univ, CNRS UMR 7288, IBDM, 13288 Marseille, France; Aix-Marseille Univ, INSERM UMR 1090, TAGC, 13288 Marseille, France; Department of Life Sciences, University of Science and Technology of Hanoi, Vietnam Academy of Science and Technology, Hanoi 10072, Vietnam, Kober F; Aix-Marseille Univ, CNRS, CRMBM, 13385 Marseille, France, Varlet I; Aix-Marseille Univ, CNRS, CRMBM, 13385 Marseille, France, Bernard M; Aix-Marseille Univ, CNRS, CRMBM, 13385 Marseille, France, Richard S; INSERM, CNRS, Université de Montpellier, PHYMEDEXP, 34295 Montpellier, France, Kelly RG; Aix-Marseille Univ, CNRS UMR 7288, IBDM, 13288 Marseille, France, Lalevée N; Aix-Marseille Univ, INSERM UMR 1090, TAGC, 13288 Marseille, France; Aix-Marseille Univ, INSERM UMR 1263, C2VN, 13005 Marseille, France, Miquerol L; Aix-Marseille Univ, CNRS UMR 7288, IBDM, 13288 Marseille, France

Publikováno v: Journal of cardiovascular development and disease [J Cardiovasc Dev Dis] 2023 Apr 27; Vol. 10 (5). Date of Electronic Publication: 2023 Apr 27.