Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Miquel À. Galmés"'
Autor:
Katarzyna Świderek, Susana Velasco-Lozano, Miquel À. Galmés, Ion Olazabal, Haritz Sardon, Fernando López-Gallego, Vicent Moliner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Biocatalysis is a key technology enabling plastic recycling. However, despite advances done in the development of plastic-degrading enzymes, the molecular mechanisms that govern their catalytic performance are poorly understood, hampering th
Externí odkaz:
https://doaj.org/article/cec1a30d701d4fe89d027e8162a31bb2
Autor:
Miquel À. Galmés, Alexander R. Nödling, Kaining He, Louis Y. P. Luk, Katarzyna Świderek, Vicent Moliner
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Universitat Jaume I
While there has been emerging interest in designing new enzymes to solve practical challenges, computer-based options to redesign catalytically active proteins are rather limited. Here, a rational QM/MM molecular dynamics strategy based on combining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d717b21af7e55c8cca313d4af299760
https://doi.org/10.1039/d2sc00778a
https://doi.org/10.1039/d2sc00778a
Autor:
Christian Lambert, Andrew J. Lees, Cristina Simonet, Miquel À Galmés, Tahrina Haque, Alastair J. Noyce, Richard N. Rees, Anette Schrag, Jonathan P. Bestwick
Publikováno v:
Journal of Parkinson's Disease. 11:1901-1915
Background: Bradykinesia is the defining motor feature of Parkinson’s disease (PD). There are limitations to its assessment using standard clinical rating scales, especially in the early stages of PD when a floor effect may be observed. Objective:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df2819c43513f9dfcc8f2a63f10c7ee
https://doi.org/10.3233/jpd-212683
https://doi.org/10.3233/jpd-212683
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Universitat Jaume I
Environmentally friendly processes are nowadays a trending topic to get highly desired chemical compounds and, in this sense, the use of enzyme-catalyzed routes is becoming a promising alternative to traditional synthetic methods. In the present pape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1b93802a446cb8d6c094c993221aa2
https://doi.org/10.1021/acs.jcim.1c00425
https://doi.org/10.1021/acs.jcim.1c00425
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Universitat Jaume I
Convergent evolution has resulted in nonhomologous enzymes that contain similar active sites that catalyze the same primary and secondary reactions. Comparing how these enzymes achieve their reaction promiscuity can yield valuable insights to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a629937521246c46672d82c250bffc66
https://orca.cardiff.ac.uk/id/eprint/143517/1/PP.pdf
https://orca.cardiff.ac.uk/id/eprint/143517/1/PP.pdf
Autor:
Jonathan P. Bestwick, Alastair J. Noyce, Cristina Simonet, Miquel À Galmés, Richard N. Rees, Tahrina Haque, Andrew J. Lees, Christian Lambert, Anette Schrag
BackgroundBradykinesia is the defining motor feature of Parkinson’s disease (PD). There are limitations to its assessment using standard clinical rating scales, especially in the early stages of PD when a floor effect may be observed.ObjectivesTo d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3672a60e2aa35115ad3713e7024c6af6
https://doi.org/10.1101/2021.03.24.21254234
https://doi.org/10.1101/2021.03.24.21254234
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Digital.CSIC. Repositorio Institucional del CSIC
instname
Universitat Jaume I
Digital.CSIC. Repositorio Institucional del CSIC
instname
Enzyme promiscuity attracts the interest of the industrial and academic sectors because of its application in the design of biocatalysts. The amidase activity of Candida antarctica lipase B (CALB) on two different substrates has been studied by theor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b4ede8d34e413effae5217261f97e6
http://hdl.handle.net/10234/189530
http://hdl.handle.net/10234/189530
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Sulfation is an important molecular modification that regulates essential cellular processes and is also implicated in numerous pathological processes. The enzymes responsible for this reaction in living organisms are sulfotransferases. The gene Hoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441a3dc5f064569b1d80ec794e2ec692
http://hdl.handle.net/10261/95814
http://hdl.handle.net/10261/95814