Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Miquéias Lopes‐Pacheco"'
Autor:
Renata de Souza Mendes, Pedro Leme Silva, Chiara Robba, Denise Battaglini, Miquéias Lopes-Pacheco, Celso Caruso-Neves, Patricia R. M. Rocco
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract This narrative review delves into the intricate interplay between the lungs and the kidneys, with a focus on elucidating the pathogenesis of diseases influenced by immunological factors, acid–base regulation, and blood gas disturbances, as
Externí odkaz:
https://doaj.org/article/0095ac7065e644cea47d2992f5b43d11
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/b86297f9fb83412299fac5f5f875e248
Publikováno v:
Molecules, Vol 29, Iss 4, p 821 (2024)
The monogenic rare disease Cystic Fibrosis (CF) is caused by mutations in the gene encoding the CF transmembrane conductance (CFTR) protein, an anion channel expressed at the apical plasma membrane of epithelial cells. The discovery and subsequent de
Externí odkaz:
https://doaj.org/article/5abfdc1f3d7343b399545f581ac76e42
Autor:
Claudia C. dos Santos, Miquéias Lopes-Pacheco, Karen English, Sara Rolandsson Enes, Anna Krasnodembskaya, Patricia R. M. Rocco
Publikováno v:
Cells, Vol 13, Iss 2, p 122 (2024)
Mesenchymal stromal cells (MSCs) and MSC-derived extracellular vesicles (EVs) have emerged as innovative therapeutic agents for the treatment of sepsis and acute respiratory distress syndrome (ARDS). Although their potential remains undisputed in pre
Externí odkaz:
https://doaj.org/article/9798bc21629e4bbb9db3e4a4dc4cc632
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Respiratory diseases remain a major health concern worldwide because they subject patients to considerable financial and psychosocial burdens and result in a high rate of morbidity and mortality. Although significant progress has been made in underst
Externí odkaz:
https://doaj.org/article/74b3b73afd7c4b349299b3c62d3e7798
Autor:
Kátia Nunes da Silva, André Luiz Nunes Gobatto, Zaquer Suzana Munhoz Costa-Ferro, Bruno Raphael Ribeiro Cavalcante, Alex Cleber Improta Caria, Luciana Souza de Aragão França, Carolina Kymie Vasques Nonaka, Fernanda de Macêdo Lima, Miquéias Lopes-Pacheco, Patricia Rieken Macêdo Rocco, Bruno Solano de Freitas Souza
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-24 (2021)
Abstract The COVID-19 pandemic, caused by the rapid global spread of the novel coronavirus (SARS-CoV-2), has caused healthcare systems to collapse and led to hundreds of thousands of deaths. The clinical spectrum of COVID-19 is not only limited to lo
Externí odkaz:
https://doaj.org/article/caf073db2e3f46a28d1bf469759bb292
Autor:
Mafalda Bacalhau, Mariana Camargo, Grace A. V. Magalhães-Ghiotto, Sybelle Drumond, Carlos Henrique M. Castelletti, Miquéias Lopes-Pacheco
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 410 (2023)
Cystic fibrosis (CF) is a potentially fatal monogenic disease that causes a progressive multisystemic pathology. Over the last decade, the introduction of CF transmembrane conductance regulator (CFTR) modulator drugs into clinical practice has profou
Externí odkaz:
https://doaj.org/article/1fab2efa0f334e8685ca0a052ac45826
Autor:
Denise Battaglini, Miquéias Lopes-Pacheco, Hugo C. Castro-Faria-Neto, Paolo Pelosi, Patricia R. M. Rocco
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes a wide spectrum of clinical manifestations, with progression to multiorgan failure in the most severe cases. Several biomarkers can be altered in coronavirus disease 2019 (COVID-19),
Externí odkaz:
https://doaj.org/article/a8066f371ec744b78cca68cd2714a107
Autor:
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 2, Pp n/a-n/a (2022)
Abstract Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a chloride and bicarbonate channel in secretory epithelia with a critical role in maintaining fluid homeostasis. Mutations in CFTR are associated with Cystic Fibrosis (CF), the mo
Externí odkaz:
https://doaj.org/article/2333634eb31448bfa35a483208141fd8
Autor:
Fabio S. Aguiar, André S. Melo, Ana Maria S. Araújo, Alexandre P. Cardoso, Sergio Augusto L. de Souza, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Debora G. Xisto, Karina D. Asensi, Lanuza Faccioli, Anna Beatriz S. Salgado, Maria Carolina P. P. Landesmann, Regina C. S. Goldenberg, Bianca Gutfilen, Marcelo M. Morales, Patricia R. M. Rocco, Jose R. Lapa e Silva
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Background Despite recent advances in understanding its pathophysiology and development of novel therapies, asthma remains a serious public health issue worldwide. Combination therapy with inhaled corticosteroids and long-acting β2-adrenoce
Externí odkaz:
https://doaj.org/article/625d3159a0524f6e83bf88b351fd567d