Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Miodrag Guzvic"'
Autor:
Maki Asami, Brian Y.H. Lam, Martin Hoffmann, Toru Suzuki, Xin Lu, Naoko Yoshida, Marcella K. Ma, Kara Rainbow, Miodrag Gužvić, Matthew D. VerMilyea, Giles S.H. Yeo, Christoph A. Klein, Anthony C.F. Perry
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112023- (2023)
Summary: At the moment of union in fertilization, sperm and oocyte are transcriptionally silent. The ensuing onset of embryonic transcription (embryonic genome activation [EGA]) is critical for development, yet its timing and profile remain elusive i
Externí odkaz:
https://doaj.org/article/58b7a14aaceb4f2b84375d76e14ddecf
Autor:
Melanie Werner-Klein, Ana Grujovic, Christoph Irlbeck, Milan Obradović, Martin Hoffmann, Huiqin Koerkel-Qu, Xin Lu, Steffi Treitschke, Cäcilia Köstler, Catherine Botteron, Kathrin Weidele, Christian Werno, Bernhard Polzer, Stefan Kirsch, Miodrag Gužvić, Jens Warfsmann, Kamran Honarnejad, Zbigniew Czyz, Giancarlo Feliciello, Isabell Blochberger, Sandra Grunewald, Elisabeth Schneider, Gundula Haunschild, Nina Patwary, Severin Guetter, Sandra Huber, Brigitte Rack, Nadia Harbeck, Stefan Buchholz, Petra Rümmele, Norbert Heine, Stefan Rose-John, Christoph A. Klein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Metastatic dissemination in breast cancer patients occurs early in malignant transformation, raising questions about how disseminated cancer cells (DCC) progress at distant sites. Here, the authors show that DCCs in bone marrow are activated via IL6-
Externí odkaz:
https://doaj.org/article/852fb79d2cfa456b923be4f3ce115b15
Autor:
Toru Suzuki, Maki Asami, Martin Hoffmann, Xin Lu, Miodrag Gužvić, Christoph A. Klein, Anthony C. F. Perry
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development
Externí odkaz:
https://doaj.org/article/6ffa962a410d45ca82f8dc8bc304e7be
Autor:
Huiqin Koerkel-Qu, Sandra Grunewald, Stefan Rose-John, Stefan Kirsch, Melanie Werner-Klein, Martin Hoffmann, Severin Guetter, Isabell Blochberger, Catherine Botteron, Elisabeth Schneider, Petra Ruemmele, Miodrag Guzvic, Stefan Buchholz, Gundula Haunschild, Kamran Honarnejad, Christoph Klein, Christoph Irlbeck, Nina Patwary, Sandra Huber, Caecilia Koestler, Kathrin Weidele, Ana Grujovic, Milan Obradovic, Zbigniew T. Czyz, Steffie Treitschke, Norbert Heine, Xin Lu, Jens Warfsmann, Bernhard Polzer, Christian Werno
Although thousands of breast cancer cells disseminate and home to bone marrow until primary surgery, usually less than a handful will succeed in establishing manifest metastases months to years later. To identify signals that support survival or outg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e8f731ee4d130ef1923858cc0248cb
https://doi.org/10.1101/2020.05.28.121145
https://doi.org/10.1101/2020.05.28.121145
Autor:
Zbigniew T. Czyz, Giancarlo Feliciello, Miodrag Guzvic, Thomas Schamberger, Sandra Grunewald, Selim Corbacioglu, Markus J. Riemenschneider, Bernhard Polzer, Christoph A. Klein
Publikováno v:
Cancer Research. 79:LB-239
Background: Clinical management of cancers of the central nevus system (CNS) is very challenging as they often exhibit low responsiveness to radiation and chemotherapy resulting in overall poor survival. Moreover, analysis of mechanisms driving cance
Autor:
Christian Werno, Kathrin Weidele, Stefan Kirsch, Catherine Botteron, Stefan Buchholz, Bernhard Polzer, Petra Rümmele, Martin Hoffmann, Milan Obradovic, Christoph Klein, Stefan Rose-John, Christoph Irlbeck, Melanie Werner-Klein, Xin Lu, Norbert Heine, Ana Grujovic, Cäcilia Köstler, Miodrag Guzvic, Steffi Treitschke
Publikováno v:
Cancer Research. 79:LB-312
While thousands of breast cancer cells disseminate and home to bone marrow (BM) until primary surgery, usually less than a handful will succeed in establishing manifest metastases months to years later. Signals and mechanisms determining failure or s
Autor:
Ludek Blaha, Brad L. Upham, Lan Lan Li, Jacob Scott, Joseph M. Carbone, Alisa M. Rummel, Chad Coe, Miodrag Guzvic, James E. Trosko
Publikováno v:
Nutrition and Cancer. 57:38-47
Dicumyl peroxide (di-CuOOH) and benzoyl peroxide (BzOOH) act as tumor promoters in SENCAR mice, whereas di-tert-butylhydroperoxide does not. Tumor promotion requires the removal of growth suppression by inhibition of gap junctional intercellular comm
Autor:
Christine Klein, Anthony E. Lang, Angela M. Kaindl, Peter P. Pramstaller, Peter Vieregge, Katja Hedrich, Christian Beetz, David Simon, Anne Grünewald, Ana Djarmati, Miodrag Guzvic, Anders O H Nygren
Publikováno v:
Movement Disorders
Because of the occurrence of different types of mutations, comprehensive genetic testing for Parkinsons disease (PD), dopa-responsive dystonia (DRD), and myoclonus-dystonia (M-D) should include screening for small sequence changes and for large exoni
Autor:
Bernhard Polzer, Miodrag Guzvic, Urs Lahrmann, Christoph Klein, Giancarlo Feliciello, Zbigniew T. Czyz, Stefan Kirsch
Publikováno v:
Cancer Research. 76:1551-1551
Introduction: Manifestation of bone metastases is the most frequent cause of death among prostate cancer patients. Since the progression from non-metastatic (M0) to metastatic (M1) is highly unpredictable, molecular analysis of disseminated cancer ce
Autor:
Katja Lohmann, Elisabeth Butz, Igor Petrović, Anne Weissbach, Marina Svetel, Vladimir S. Kostic, Ana Djarmati, Reiner Siebert, Christine Klein, Nataša Dragašević, Miodrag Guzvic, Aleksandar Rakovic, Christine Zühlke, Holger Tönnies
Publikováno v:
Movement Disorders
Autosomal dominant spinocerebellar ataxias (SCAs) are a clinically and genetically heterogeneous group of neurodegenerative disorders. We investigated an SCA family from Serbia of Roma ethnic origin; four affected and nine unaffected family members u