Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Minzhi Zhao"'
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract A nano‐enabled drug delivery acupuncture technology (nd‐Acu) is developed that is based on traditional acupuncture needles where the stainless‐steel surface is designed to deliver various payload molecules. To create the nd‐Acu platf
Externí odkaz:
https://doaj.org/article/254d1a36f4c74ec78753c4776cf9b79c
Publikováno v:
Journal of Materials Science: Materials in Medicine, Vol 33, Iss 2, Pp 1-11 (2022)
Abstract The MR/FI bimodal imaging has attracted widely studied due to combining the advantages of MRI and FI can bridge gaps in sensitivity and depth between these two modalities. Herein, a novel MR/FI bimodal imaging probe is facile fabricated by c
Externí odkaz:
https://doaj.org/article/2bd935c9dd56482f9a863959f445372f
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Antibody therapies have huge potential in treating cancer but currently suffer from problems with delivery. Here the authors report on a study into then conjugation of Ramucirumab to gold nanoparticles to improve delivery and add theranostic capabili
Externí odkaz:
https://doaj.org/article/c0796a15b6a146ae8c4ca7d66a98469c
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 47, Iss 1, Pp 684-694 (2019)
Plastin 3 (PLS3) overexpression may serve as a marker for predicting chemotherapeutic outcomes in drug-resistant cancer cells, but the mechanism is unclear. Herein, we show that the down-regulation of PLS3 by PLS3 gene silencing augments the sensitiv
Externí odkaz:
https://doaj.org/article/8f9253b85c8e4126b8a0da71cf673051
Autor:
Minzhi Zhao, Chunni Lei, Yadong Yang, Xiangli Bu, Huailei Ma, He Gong, Juan Liu, Xiangdong Fang, Zhiyuan Hu, Qiaojun Fang
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131429 (2015)
P-glycoprotein (P-gp) can actively pump paclitaxel (PTX) out of cells and induces drug resistance. Abraxane, a nanoparticle (NP) formulation of PTX, has multiple clinical advantages over the single molecule form. However, it is still unclear whether
Externí odkaz:
https://doaj.org/article/9ba5b5eff5624dd4a1f5c5ec69abdec6
Publikováno v:
Journal of Rare Earths. 40:1098-1105
Gadolinium (III)-based T1 contrast agent have been widely used in clinical MRI. In this study, salicylic acid-gadolinium chelate was prepared via directly coordination reaction of gadolinium ion and salicylic acid. Then, three polyethylene glycols wi
Publikováno v:
Journal of Biomedical Nanotechnology. 17:1635-1646
Due to the combination of the high resolution of fluorescence imaging and the no limitation in penetration depth of magnetic resonance imaging, dual-mode imaging of magnetic resonance and fluorescence (MR/FI) have attracted extensive research in rece
Autor:
Limin Zhang, Zhenqi Jiang, Xi Yang, Yixia Qian, Minxuan Wang, Shang Wu, Lingyun Li, Fei Jia, Zihua Wang, Zhiyuan Hu, Minzhi Zhao, Xiaoying Tang, Gang Li, Hanbing Shang, Xiaoyuan Chen, Weizhi Wang
Publikováno v:
Advanced materials (Deerfield Beach, Fla.).
Immune checkpoint blockade combined with reversal of the immunosuppressive tumor microenvironment (TME) can dramatically enhance anti-tumor immunity, which can be achieved by using multiple-agent therapy. However, the optimal dose and order of admini
Publikováno v:
New Journal of Chemistry. 45:18544-18551
Herein, the clinically approved nitrogen mustard, chlorambucil (Chl), is covalently embedded into a poly(N-(2-hydroxypropyl)methacrylamide, HPMA) vector via a hydrolysable ester bond to overcome the shortcomings of Chl as well as to achieve better ef
Autor:
Yanlian Yang, Ping Li, Linyang Fan, Ying Zhou, Qin Li, Zihua Wang, Xiaoyi Chong, Lin Shen, Fei Jia, Xiaotian Zhang, Minzhi Zhao, Qiongrong Huang, Zhiyuan Hu, Xiao Lu
Publikováno v:
Analytical Chemistry. 93:665-670
Gastric cancer (GC) is a major global cancer burden, and only HER2-targeted therapies have been approved in first line clinical therapy. CLDN18.2 has been regarded as a potential therapeutic target for gastrointestinal tumors, and global clinical tri