Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Minwoo Pak"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Drug response prediction, especially in terms of cell viability prediction, is a well-studied research problem with significant implications for personalized medicine. It enables the identification of the most effective drugs based on i
Externí odkaz:
https://doaj.org/article/55a1a3f3af7848f2af418fd08d7084c3
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S3, Pp 1-19 (2022)
Abstract Background The widely spreading coronavirus disease (COVID-19) has three major spreading properties: pathogenic mutations, spatial, and temporal propagation patterns. We know the spread of the virus geographically and temporally in terms of
Externí odkaz:
https://doaj.org/article/5d5542b0f6f2427fb1ecfac0898c0b5e
Publikováno v:
BMC Medical Genomics, Vol 13, Iss S3, Pp 1-14 (2020)
Abstract Background In cancer, mutations of DNA methylation modification genes have crucial roles for epigenetic modifications genome-wide, which lead to the activation or suppression of important genes including tumor suppressor genes. Mutations on
Externí odkaz:
https://doaj.org/article/1e3eac32bf0d4f1ca139f360f91a562b
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Transcription factor (TF) has a significant influence on the state of a cell by regulating multiple down-stream genes. Thus, experimental and computational biologists have made great efforts to construct TF gene networks for regulatory interactions b
Externí odkaz:
https://doaj.org/article/ad778022d9254101ad6b8298641766e7
Publikováno v:
Journal of KIISE. 49:261-270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::430f0eb847ec5f3204dba31926cb45ec
https://doi.org/10.5626/jok.2022.49.4.261
https://doi.org/10.5626/jok.2022.49.4.261
Autor:
Ye Young Kim, Hagoon Jang, Gung Lee, Yong Geun Jeon, Jee Hyung Sohn, Ji Seul Han, Won Taek Lee, Jeu Park, Jin Young Huh, Hahn Nahmgoong, Sang Mun Han, Jeesoo Kim, Minwoo Pak, Sun Kim, Jong-Seo Kim, Jae Bum Kim
Publikováno v:
Diabetes. 71:1373-1387
Excessive hepatic glucose production (HGP) is a key factor promoting hyperglycemia in diabetes. Hepatic cryptochrome 1 (CRY1) plays an important role in maintaining glucose homeostasis by suppressing forkhead box protein O1 (FOXO1)-mediated HGP. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c2b3231822891cb3d656ff01634366
https://doi.org/10.2337/db21-0649
https://doi.org/10.2337/db21-0649
Publikováno v:
IEEE/ACM transactions on computational biology and bioinformatics. 19(4)
Identifying differentially expressed genes (DEGs) in transcriptome data is a very important task. However, performances of existing DEG methods vary significantly for data sets measured in different conditions and no single statistical or machine lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82827d99c760d8af92d2116525a8d35e
https://pubmed.ncbi.nlm.nih.gov/33750713
https://pubmed.ncbi.nlm.nih.gov/33750713
Publikováno v:
Recent Advances in Biological Network Analysis ISBN: 9783030571726
Network propagation has been used as the state-of-the-art network analysis method which can overcome the limitations of the existing methods. The area where network propagation truly shines is the application to multi-omics data. It integrates intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::725c32af79db885bf778e821da61df0f
https://doi.org/10.1007/978-3-030-57173-3_9
https://doi.org/10.1007/978-3-030-57173-3_9
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 13, Iss S3, Pp 1-14 (2020)
BMC Medical Genomics, Vol 13, Iss S3, Pp 1-14 (2020)
Background In cancer, mutations of DNA methylation modification genes have crucial roles for epigenetic modifications genome-wide, which lead to the activation or suppression of important genes including tumor suppressor genes. Mutations on the epige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26118749d8f73a842c07b2bcd0480980
https://doi.org/10.1186/s12920-020-0659-4
https://doi.org/10.1186/s12920-020-0659-4
Additional file 1 Figure S1 Case ratio of 7 DNA methylation modifiers mutations in each TCGA 33 projects. Figure S2 Violin plot result of DMR analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4ff8110e622a17c96485145a899c0b