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Assessment of Efficacy and Safety of Zagotenemab: Results From PERISCOPE-ALZ, a Phase 2 Study in Early Symptomatic Alzheimer Disease.

Autor: Fleisher AS; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Munsie LM; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Perahia DGS; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Andersen SW; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Higgins IA; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Hauck PM; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Lo AC; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Sims JR; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Brys M; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA., Mintun M; From Eli Lilly and Company, Indianapolis, IN. Dr. A.C. Lo is currently at Kisbee Therapeutics, Cambridge, MA.

Publikováno v: Neurology [Neurology] 2024 Mar 12; Vol. 102 (5), pp. e208061. Date of Electronic Publication: 2024 Feb 22.

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Akademický článek

Alzheimer's disease therapeutic trials: EU/US task force report on recruitment, retention, and methodology

Autor: Vellas, B. ^*, Hampel, H. ^*, Rouge-Bugat, M.E. ^*, Grundman, M. ^*, Andrieu, S. ^*, Abu-Shakra, S. ^*, Bateman, R. ^*, Berman, R. ^*, Black, R. ^*, Carrillo, M. ^*, Donohue, M. ^*, Mintun, M. ^*, Morris, J. ^*, Petersen, R. ^*, Thomas, R.G. ^*, Suhy, J. ^*, Schneider, L. ^*, Seely, L. ^*, Tariot, P. ^*, Touchon, J. ^*, Weiner, M. ^*, Sampaio, C. ^*, Aisen, P. ^*

Publikováno v: In The Journal of nutrition, health and aging April 2012 16(4):339-345

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Akademický článek

Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial.

Autor: Sims JR; Eli Lilly and Company, Indianapolis, Indiana., Zimmer JA; Eli Lilly and Company, Indianapolis, Indiana., Evans CD; Eli Lilly and Company, Indianapolis, Indiana., Lu M; Eli Lilly and Company, Indianapolis, Indiana., Ardayfio P; Eli Lilly and Company, Indianapolis, Indiana., Sparks J; Eli Lilly and Company, Indianapolis, Indiana., Wessels AM; Eli Lilly and Company, Indianapolis, Indiana., Shcherbinin S; Eli Lilly and Company, Indianapolis, Indiana., Wang H; Eli Lilly and Company, Indianapolis, Indiana., Monkul Nery ES; Eli Lilly and Company, Indianapolis, Indiana., Collins EC; Eli Lilly and Company, Indianapolis, Indiana., Solomon P; Boston Center for Memory and Boston University Alzheimer's Disease Center, Boston, Massachusetts., Salloway S; Department of Neurology and Department of Psychiatry, Alpert Medical School of Brown University, Providence, Rhode Island.; Butler Hospital, Providence, Rhode Island., Apostolova LG; Department of Neurology, Indiana University School of Medicine, Indianapolis., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden; Memory Clinic, Skåne University Hospital, Lund, Sweden., Ritchie C; Scottish Brain Sciences, Edinburgh, United Kingdom., Brooks DA; Eli Lilly and Company, Indianapolis, Indiana., Mintun M; Eli Lilly and Company, Indianapolis, Indiana., Skovronsky DM; Eli Lilly and Company, Indianapolis, Indiana.

Publikováno v: JAMA [JAMA] 2023 Aug 08; Vol. 330 (6), pp. 512-527.

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Parametric imaging of tau load in Alzheimer's patients and controls using Flortaucipir

Autor: Golla, S. S. V., Wolters, E., Timmers, T., Ossenkoppele, R., Groot, C., Verfaillie, S., Scheltens, P., van der Flier, W. M., Schwarte, L., Mintun, M. A., Devous, M., Schuit, R. C., Windhorst, A. D., Lammertsma, A. A., Boellaard, R., van Berckel, B. N. M., Yaqub, M.

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging, 44, S250-S251. Springer Verlag
Golla, S S V, Wolters, E, Timmers, T, Ossenkoppele, R, Groot, C, Verfaillie, S, Scheltens, P, van der Flier, W M, Schwarte, L, Mintun, M A, Devous, M, Schuit, R C, Windhorst, A D, Lammertsma, A A, Boellaard, R, van Berckel, B N M & Yaqub, M 2017, ' Parametric imaging of tau load in Alzheimer's patients and controls using Flortaucipir ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, pp. S250-S251 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e114bcfcb37e5a9969ff56292934aebb
https://research.vumc.nl/en/publications/f2067282-d7d9-49e7-91db-a8616f686f19

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Association between tau deposition and antecedent amyloid-beta accumulation rates in normal and early symptomatic individuals

Autor: Tosun, D, Landau, S, Aisen, PS, Petersen, RC, Mintun, M, Jagust, W, Weiner, MW, Neuroimaging, AD

Publikováno v: Tosun, D; Landau, S; Aisen, PS; Petersen, RC; Mintun, M; Jagust, W; et al.(2017). Association between tau deposition and antecedent amyloid-beta accumulation rates in normal and early symptomatic individuals. BRAIN, 140, 1499-1512. doi: 10.1093/brain/awx046. UCSF: Retrieved from: http://www.escholarship.org/uc/item/4dj5g3zt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7cac0f3e7c4c68b39ebd483ceae8680e
http://www.escholarship.org/uc/item/4dj5g3zt

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Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Autor: Young, A. L., Marinescu, R. V., Oxtoby, N. P., Bocchetta, M., Yong, K., Firth, N. C., Cash, D. M., Thomas, D. L., Dick, K. M., Cardoso, J., van Swieten, J., Borroni, B., Galimberti, D., Masellis, M., Tartaglia, M. C., Rowe, J. B., Graff, C., Tagliavini, F., Frisoni, G. B., Laforce, R., Finger, E., de Mendonca, A., Sorbi, S., Warren, J. D., Crutch, S., Fox, N. C., Ourselin, S., Schott, J. M., Rohrer, J. D., Alexander, D. C., Andersson, C., Archetti, S., Arighi, A., Benussi, L., Binetti, G., Black, S., Cosseddu, M., Fallstrom, M., Ferreira, C., Fenoglio, C., Freedman, M., Fumagalli, G. G., Gazzina, S., Ghidoni, R., Grisoli, M., Jelic, V., Jiskoot, L., Keren, R., Lombardi, G., Maruta, C., Meeter, L., Mead, S., van Minkelen, R., Nacmias, B., Oijerstedt, L., Padovani, A., Panman, J., Pievani, M., Polito, C., Premi, E., Prioni, S., Rademakers, R., Redaelli, V., Rogaeva, E., Rossi, G., Rossor, M., Scarpini, E., Tang-Wai, D., Thonberg, H., Tiraboschi, P., Verdelho, A., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Khachaturian, Z., Sorensen, G., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Thompson, P., Schuff, N., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Leon, S., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., de Toledo-Morrell, L., Shah, R. C., Duara, R., Varon, D., Greig, M. T., Roberts, P., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Rusinek, H., de Leon, M. J., Glodzik, L., De Santi, S., Doraiswamy, P. M., Petrella, J. R., Wong, T. Z., Arnold, S. E., Karlawish, J. H., Wolk, D., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., Devous, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Anderson, H. S., Swerdlow, R. H., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H., P. H., Lu, Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Matthews, B. R., Herring, S., Hunt, C., van Dyck, C. H., Carson, R. E., Macavoy, M. G., Chertkow, H., Bergman, H., Hosein, C., Stefanovic, B., Caldwell, C., Hsiung, G. -Y. R., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Bernick, C., Munic, D., Kerwin, D., Mesulam, M. -M., Lipowski, K., C. -K., Wu, Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Frey, M., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Allard, J., Lerner, A., Ogrocki, P., Hudson, L., Fletcher, E., Carmichael, O., Olichney, J., Decarli, C., Kittur, S., Borrie, M., Lee, T. -Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Santulli, R. B., Kitzmiller, T. J., Schwartz, E. S., Sink, K. M., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Mintzer, J., Spicer, K., Bachman, D., Pasternak, S., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ponto, L. L. B., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K., Raj, B. A., Neylan, T., Grafman, J., Davis, M., Morrison, R., Hayes, J., Finley, S., Friedl, K., Fleischman, D., Arfanakis, K., James, O., Massoglia, D., Fruehling, J. J., Harding, S., Peskind, E. R., Petrie, E. C., Li, G., Yesavage, J. A., Taylor, J. L., Furst, A. J.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3432::ba93a506ee5ed3c6b9bc79e3ae6958f1
https://www.nature.com/articles/s41467-018-05892-0

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Measurement of longitudinal β-amyloid change with 18F-florbetapir PET and standardized uptake value ratios

Autor: Landau, SM, Fero, A, Baker, SL, Koeppe, R, Mintun, M, Chen, K, Reiman, EM, Jagust, WJ

Publikováno v: Landau, SM; Fero, A; Baker, SL; Koeppe, R; Mintun, M; Chen, K; et al.(2015). Measurement of longitudinal β-amyloid change with 18F-florbetapir PET and standardized uptake value ratios. Journal of Nuclear Medicine, 56(4), 567-574. doi: 10.2967/jnumed.114.148981. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/4tt9m535

COPYRIGHT © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc. The accurate measurement of β-amyloid (Aβ) change using amyloid PET imaging is important for Alzheimer disease research and clinical trials but poses several unique ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::f30756de53664a13a657b7f8ec5f28bd
http://www.escholarship.org/uc/item/4tt9m535

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