Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Minsuh Seo"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24179 (2011)
Cancer cells adopt glycolysis as the major source of metabolic energy production for fast cell growth. The HIF-1-induced PFKFB3 plays a key role in this adaptation by elevating the concentration of Fru-2,6-BP, the most potent glycolysis stimulator. A
Externí odkaz:
https://doaj.org/article/15faa9a7ff044596a72b477c795121b8
Autor:
Yong Hwan Lee, Minsuh Seo
Publikováno v:
Journal of Molecular Biology. 426:830-842
Whereas moderately increased cellular oxidative stress is supportive for cancerous growth of cells, excessive levels of reactive oxygen species (ROS) is detrimental to their growth and survival. We demonstrated that high ROS levels, via increased oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82653aa1ab7ad3c384473556c14c542
https://doi.org/10.1016/j.jmb.2013.11.021
https://doi.org/10.1016/j.jmb.2013.11.021
Autor:
Minsuh Seo, Yong Hwan Lee, Michael C. Cavalier, Robert B. Crochet, Seung-Jong Park, Young Sun Yim, Jeong Do Kim
Publikováno v:
Analytical Biochemistry. 418:143-148
Efforts toward improving the predictiveness in tier-based approaches to virtual screening (VS) have mainly focused on protein kinases. Despite their significance as drug targets, small molecule kinases have been rarely tested with these approaches. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74324485529e31a8126f3a2d2a634919
https://doi.org/10.1016/j.ab.2011.06.035
https://doi.org/10.1016/j.ab.2011.06.035
Autor:
Paola B. Arimondo, Christian Bailly, Tracy M. Bryan, Silvia Chioato, Scott B. Cohen, Ian Collins, Robert Blake Crochet, Nicola J. Curtin, William A. Denny, Erling Donnelly, Daniele Generali, Nicolas Guilbaud, Ian R. Hardcastle, Adrian L. Harris, Philip A. Harris, John A. Hartley, Rolf W. Hartmann, Qingzhong Hu, Donna M. Huryn, Federico Innocenti, Harren Jhoti, Keith Jones, Yong-Hwan Lee, David Norton, Puja Pathuri, Gordon W. Rewcastle, Minsuh Seo, Swee Sharp, Zahid H. Siddik, Christopher A. Slapak, Ross Soo, Malcolm F.G. Stevens, David Taylor, Dominic Tisi, Christopher G. Tomlinson, Stephany Veuger, Richard A. Walgren, Henriette Willems, Peter Wipf, Paul Workman, Wei-Peng Yong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b905b2a0c73213819471cd451da75b1d
https://doi.org/10.1016/b978-0-12-396521-9.01002-0
https://doi.org/10.1016/b978-0-12-396521-9.01002-0
Since the first theorization of the Warburg effect as a metabolic characteristic of cancer, a great deal of progress has been made in the understanding of molecular details underlying the metabolic alterations that cancer cells evolved for survival a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483aae825017c371a4c9fe87fca4a66d
https://doi.org/10.1016/b978-0-12-396521-9.00014-0
https://doi.org/10.1016/b978-0-12-396521-9.00014-0