Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Minru Liao"'
Autor:
Fu Peng, Minru Liao, Wenke Jin, Wei Liu, Zixiang Li, Zhichao Fan, Ling Zou, Siwei Chen, Lingjuan Zhu, Qian Zhao, Gu Zhan, Liang Ouyang, Cheng Peng, Bo Han, Jin Zhang, Leilei Fu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Sirtuin 3 (SIRT3) is well known as a conserved nicotinamide adenine dinucleotide+ (NAD+)-dependent deacetylase located in the mitochondria that may regulate oxidative stress, catabolism and ATP production. Accumulating evidence has recently
Externí odkaz:
https://doaj.org/article/0c9da444ccf442e3b3e6e2e182b75a0c
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 953-1008 (2024)
Cancer reprogramming is an important facilitator of cancer development and survival, with tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation, even under sufficient oxygen supply condition. This metabolic alter
Externí odkaz:
https://doaj.org/article/b1779bcc927d448d852dc2aff14b0f97
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 10, Pp 3743-3782 (2022)
UNC-51-like kinase 1 (ULK1), as a serine/threonine kinase, is an autophagic initiator in mammals and a homologous protein of autophagy related protein (Atg) 1 in yeast and of UNC-51 in Caenorhabditis elegans. ULK1 is well-known for autophagy activati
Externí odkaz:
https://doaj.org/article/3879a3cb86364c6cbe288cc37f89ea18
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-66 (2022)
Abstract Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the form of cell death that can be regulated by a variety of biomacromolecules, which is distinctive from accidental cell death (ACD). Accumulating evidenc
Externí odkaz:
https://doaj.org/article/1d86f272f227411babae838ca74383ef
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-44 (2022)
Abstract Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell death (RCD), also known as programmed cell death (PCD), has
Externí odkaz:
https://doaj.org/article/2b76e095c89c43f1920c6490ad8be1c8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15121 (2023)
Paclitaxel, a natural anticancer drug, is widely recognized and extensively utilized in the treatment of breast cancer (BC). However, it may lead to certain side effects or drug resistance. Fortunately, combination therapy with another anti-tumor age
Externí odkaz:
https://doaj.org/article/8363f77cc3ed4082b8cc6609626b31ca
Publikováno v:
Molecules, Vol 28, Iss 9, p 3897 (2023)
Natural astaxanthin has been widely used in the food, cosmetic, and medicine industries due to its exceptional biological activity. Shrimp shell is one of the primary natural biological sources of astaxanthin. However, after astaxanthin recovery, the
Externí odkaz:
https://doaj.org/article/040979ac95fd443c85d2609ff32e8d0d
Publikováno v:
Journal of Medicinal Chemistry. 64:2382-2418
Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, but an effective targeted therapy has not been well-established so far. Considering the lack of effective targets, where do we go next in the current TNBC drug deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fb34ce84bb9c8acd7498a5dbff8cc8
https://doi.org/10.1021/acs.jmedchem.0c01180
https://doi.org/10.1021/acs.jmedchem.0c01180
Publikováno v:
Drug Discovery Today. 26:817-825
Folate-mediated one-carbon metabolism (FOCM) supports vital events for the growth and survival of proliferating cells. Nucleotide synthesis and DNA methylation are the biochemical bases of cancers that are highly dependent on FOCM. Recent studies rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69ba06e660bd59330111ea4afbf67a1
https://doi.org/10.1016/j.drudis.2020.12.006
https://doi.org/10.1016/j.drudis.2020.12.006
Autor:
Minru Liao, Qiang Xie, Yuqian Zhao, Chengcan Yang, Congcong Lin, Guan Wang, Bo Liu, Lingjuan Zhu
Publikováno v:
Pharmacological research. 176
Heart failure (HF), the main cause of death in patients with many cardiovascular diseases, has been reported to be closely related to the complicated pathogenesis of autophagy, apoptosis, and inflammation. Notably, Si-Miao-Yong-An decoction (SMYAD) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974aa236dc89018184db528e3121c057
https://pubmed.ncbi.nlm.nih.gov/35026404
https://pubmed.ncbi.nlm.nih.gov/35026404