Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Minou, Bina"'
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Background In mammals, Imprinting Control Regions (ICRs) regulate a subset of genes in a parent-of-origin-specific manner. In both human and mouse, previous studies identified a set of CpG-rich motifs occurring as clusters in ICRs and germli
Externí odkaz:
https://doaj.org/article/2a2f01e66bb44325a76333db2ff78c46
Autor:
Minou Bina
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Genomic imprinting is a process thereby a subset of genes is expressed in a parent-of-origin specific manner. This evolutionary novelty is restricted to mammals and controlled by genomic DNA segments known as Imprinting Control Re
Externí odkaz:
https://doaj.org/article/17fc90b44a5d45ca81a036a42aab001e
Publikováno v:
Data in Brief, Vol 13, Iss , Pp 202-207 (2017)
While MLL1 activates gene expression in most tissues, ZFP57 represses transcription. MLL1 selectively interacts with a group of nonmethylated DNA sequences known as the MLL1 morphemes. ZFP57 associates with a methylated hexamer (ZFBS), dispersed in t
Externí odkaz:
https://doaj.org/article/ff8577ba5eda4431b993d6c7bcb8b99e
Background In mammals, Imprinting Control Regions (ICRs) regulate a subset of genes in a parent-of-origin-specific manner. In both human and mouse, previous studies identified a set of CpG-rich motifs occurring as clusters in ICRs and germline Differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ef28720477464e67f9f57f964e1b87
https://doi.org/10.1101/2021.12.27.474271
https://doi.org/10.1101/2021.12.27.474271
Publikováno v:
Data in Brief, Vol 13, Iss, Pp 202-207 (2017)
Department of Chemistry Faculty Publications
Data in Brief
Department of Chemistry Faculty Publications
Data in Brief
While MLL1 activates gene expression in most tissues, ZFP57 represses transcription. MLL1 selectively interacts with a group of nonmethylated DNA sequences known as the MLL1 morphemes. ZFP57 associates with a methylated hexamer (ZFBS), dispersed in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd55be7115a3de15cfd5b86080b4003
https://doi.org/10.1016/j.dib.2017.05.050
https://doi.org/10.1016/j.dib.2017.05.050
Autor:
Minou Bina
Additional file 1 Figure S1. A candidate ICR for PRDM8. Large scale experimental studies listed PRDM8 as acandidate imprinted gene [15]. Due to its vicinity to a robust density peak, my strategy also predicts that PRDM8 is potential imprinted gene. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bf9819964dc30b7ed46440f04d0291
Autor:
Minou Bina, Phillip J. Wyss
In mammals, parent-of-origin-specific gene expression is regulated by specific genomic DNA segments known as Imprinting Control Regions (ICRs) and germline Differentially Methylated Regions (gDMRs). In the mouse genome, the known ICRs/gDMRs often inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64003154b9698b65dd9572b108eea08
Autor:
Minou Bina
Publikováno v:
BMC Genomics
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
Background Genomic imprinting is a process thereby a subset of genes is expressed in a parent-of-origin specific manner. This evolutionary novelty is restricted to mammals and controlled by genomic DNA segments known as Imprinting Control Regions (IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cf335c25f23bc8de08aa84ab17b422
Autor:
Phillip J. Wyss, Minou Bina
Publikováno v:
Biopolymers. 103:480-490
Previous studies have shown that Mixed Lineage Leukemia 1 (MLL1 or MLL) binds a group of CpG-rich motifs known as morphemes. To examine whether occurrences of MLL1 morphemes in genomic DNA may influence codon utilization, we analyzed the frequency of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d1ac081a6b0a015c82c2c8ba0e38523
https://doi.org/10.1002/bip.22681
https://doi.org/10.1002/bip.22681
Autor:
Minou Bina
The human H19 and IGF2 genes share an Imprinting Control Region (ICR) that regulates gene expression in a parent-of-origin dependent manner. Understanding of the ICR sequence organization is critical to accurate localization of disease-associated abn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abab47169221872a19fa033ea0b0bd87
https://doi.org/10.1101/250407
https://doi.org/10.1101/250407