Zobrazeno 1 - 10
of 1 638
pro vyhledávání: '"Minoru Yoshida"'
Autor:
Nobuto Nakanishi, Keibun Liu, Junji Hatakeyama, Akira Kawauchi, Minoru Yoshida, Hidenori Sumita, Kyohei Miyamoto, Kensuke Nakamura
Publikováno v:
Journal of Intensive Care, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Post-intensive care syndrome (PICS) is the long-lasting impairment of physical functions, cognitive functions, and mental health after intensive care. Although a long-term follow-up is essential for the successful management of PI
Externí odkaz:
https://doaj.org/article/a8855e13974044039020cdc7cb0c9dbc
Autor:
Kazuya Ichikado, Hidenori Ichiyasu, Kazuhiro Iyonaga, Kodai Kawamura, Noritaka Higashi, Takeshi Johkoh, Kiminori Fujimoto, Jun Morinaga, Minoru Yoshida, Katsuhiko Mitsuzaki, Moritaka Suga, Naoya Tanabe, Tomohiro Handa, Toyohiro Hirai, Takuro Sakagami
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Interstitial lung abnormalities (ILAs) are subtle or mild parenchymal abnormalities observed in more than 5% of the lungs on computed tomography (CT) scans in patients in whom interstitial lung disease was not previously clinicall
Externí odkaz:
https://doaj.org/article/f9e0f2886d88481f82a9700e9df37781
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The expression of heterologous genes is an important technique in yeast genetics. In fission yeast, the leu1 and ura4 genes have been used mainly as selectable markers for heterologous expression. To expand the repertoire of selection marker
Externí odkaz:
https://doaj.org/article/f22e7c1cc36742f094d532a64a136d0c
Autor:
Shohei Takase, Takashi Hiroyama, Fumiyuki Shirai, Yuki Maemoto, Akiko Nakata, Mayumi Arata, Seiji Matsuoka, Takeshi Sonoda, Hideaki Niwa, Shin Sato, Takashi Umehara, Mikako Shirouzu, Yosuke Nishigaya, Tatsunobu Sumiya, Noriaki Hashimoto, Ryosuke Namie, Masaya Usui, Tomokazu Ohishi, Shun-ichi Ohba, Manabu Kawada, Yoshihiro Hayashi, Hironori Harada, Tokio Yamaguchi, Yoichi Shinkai, Yukio Nakamura, Minoru Yoshida, Akihiro Ito
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
This study describes RK-701, an inhibitor of histone methyltransferases G9a/GLP, as a promising therapeutic candidate for sickle cell disease and a universal role of BGLT3 lncRNA in fetal hemoglobin reactivation by chemical inducers including RK-701.
Externí odkaz:
https://doaj.org/article/854cca959e544001b639a7418e25c89f
Autor:
Haomin Yan, Tsutomu Sasaki, Hideaki Kanki, Yoshiyuki Hirata, Kumiko Nishiyama, Sunao Hisada, Shigenobu Matsumura, Yasuo Nagaoka, Takaaki Sumiyoshi, Seiichi Nagano, Akiko Nakata, Minoru Yoshida, Shinichi Uesato, Hideki Mochizuki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Mdmx and Mdm2 are two major suppressor factors for the tumor suppressor gene p53. In central nervous system, Mdmx suppresses the transcriptional activity of p53 and enhances the binding of Mdm2 to p53 for degradation. But Mdmx dynamics in ce
Externí odkaz:
https://doaj.org/article/d535ef55554745bdb1de765b94ef736c
Autor:
Akihito Suzuki, Minoru Yoshida
Publikováno v:
Results in Optics, Vol 12, Iss , Pp 100474- (2023)
We propose a new design for a dispersion-flattened photonic crystal fiber with 800 nm wide low-dispersion band by employing the imaginary-distance beam propagation method and the transparent boundary condition using BeamPROP simulation software. The
Externí odkaz:
https://doaj.org/article/7d7cb0cc65d641359ea33a5070c94901
Autor:
Po-Chang Chiu, Yuri Nakamura, Shinichi Nishimura, Toshitsugu Tabuchi, Yoko Yashiroda, Go Hirai, Akihisa Matsuyama, Minoru Yoshida
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Microorganisms and plants produce siderophores, which function to transport environmental iron into cells as well as participate in cellular iron use and deposition. Their biological functions are diverse although their role in primary metab
Externí odkaz:
https://doaj.org/article/f8b31ac44cb9474fb85f3aa1151e56de
Autor:
Nicole M. Revie, Kali R. Iyer, Michelle E. Maxson, Jiabao Zhang, Su Yan, Caroline M. Fernandes, Kirsten J. Meyer, Xuefei Chen, Iwona Skulska, Meea Fogal, Hiram Sanchez, Saif Hossain, Sheena Li, Yoko Yashiroda, Hiroyuki Hirano, Minoru Yoshida, Hiroyuki Osada, Charles Boone, Rebecca S. Shapiro, David R. Andes, Gerard D. Wright, Justin R. Nodwell, Maurizio Del Poeta, Martin D. Burke, Luke Whitesell, Nicole Robbins, Leah E. Cowen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
There is an urgent need for novel strategies to combat life-threatening fungal infections. Here, Revie et al. identify a compound that induces alterations in fungal membranes, synergizes with azole antifungals against the pathogen Candida albicans, a
Externí odkaz:
https://doaj.org/article/8bca44075efb4f07a12ae3b736c09d4d
Autor:
Jing Yan, Hengsen Zhang, Yuna Tomochika, Bin Chen, Yashuang Ping, Md. Shoriful Islam, Shuhei Aramaki, Tomohito Sato, Yu Nagashima, Tomohiko Nakamura, Tomoaki Kahyo, Daita Kaneda, Kenji Ogawa, Minoru Yoshida, Mitsutoshi Setou
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2491 (2023)
Ubiquitin-like 3 (UBL3) is a membrane-anchored protein that plays a crucial role in sorting proteins into small extracellular vesicles. Aggregations of alpha-synuclein (α-syn) are associated with the pathology of neurodegenerative diseases such as P
Externí odkaz:
https://doaj.org/article/047015a132c240059fa05b24d272318d
Autor:
Mayuki Sasaki, Shinichi Nishimura, Yoko Yashiroda, Akihisa Matsuyama, Hideaki Kakeya, Minoru Yoshida
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105659- (2022)
Summary: FK506-binding protein with a molecular weight of 12 kDa (FKBP12) is a receptor of the immunosuppressive drugs, FK506 and rapamycin. The physiological functions of FKBP12 remain ambiguous because of its nonessentiality and multifunctionality.
Externí odkaz:
https://doaj.org/article/ac8ed75078e34e58b9b68fb12e9be41b