Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Minoru Uchiyama"'
Publikováno v:
Xenobiotica. 52:54-64
Autor:
Naotoshi, Yamamura, Jeanne, Mendel-Harary, Karen, Brown, Minoru, Uchiyama, Yoko, Urasaki, Makoto, Takahashi, Vance, Warren, Vijay, Vashi
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 51(5)
The metabolism, excretion, and pharmacokinetics of mirogabalin were investigated following a single oral administration of [
Autor:
George Zhang, Satoshi Inoue, Alexander G. Vandell, Joseph Pav, Nobuhisa Masuda, Roohi Gajee, Giorgio Senaldi, Minoru Uchiyama, Justin Dennie, Makiko Yamada, Cynthia Zamora
Publikováno v:
Journal of clinical pharmacology. 58(12)
DS-2969b is a novel GyrB inhibitor in development for the treatment of Clostridium difficile infection. The aim of this study was to assess the safety, tolerability, pharmacokinetics, and effects on normal gastrointestinal microbiota groups of single
Publikováno v:
General and Comparative Endocrinology. 209:106-117
We identified two ghrelin receptor isoforms, the ghrelin receptor type-1a (GHS-R1a) and its alternativesplice form (GHS-R1b) for West African lungfish, Protopterus annectens. Lungfish GHS-R1a and 1b com-prised 361 and 281 amino acids, respectively
Autor:
Norifumi Konno, Minoru Uchiyama, Takao Mukuda, Kouhei Matsuda, Hiroyuki Kaiya, Yuya Fujii, Haruka Imae, Mikiya Miyazato
Publikováno v:
General and Comparative Endocrinology. 185:44-56
Urotensin II (UII) and UII-related peptide (URP) exhibit diverse physiological actions including vasoconstriction, locomotor activity, osmoregulation, and immune response through UII receptor (UTR), which is expressed in the central nervous system an
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences. 279:4795-4802
Epithelial sodium channel (ENaC) is a Na + -selective, aldosterone-stimulated ion channel involved in sodium transport homeostasis. ENaC is rate-limiting for Na + absorption in the epithelia of osmoregulatory organs of tetrapods. Although the ENaC/de
Autor:
Tes Toop, Norifumi Konno, Yoko Yamaguchi, Eri Iwata, Byrappa Venkatesh, Susumu Hyodo, Mikiya Miyazato, John A. Donald, Minoru Uchiyama, Justin D. Bell, Sydney Brenner, Hiroyuki Kaiya
Publikováno v:
General and Comparative Endocrinology. 178:519-528
The neurohypophysial peptides of the vasopressin (VP) and oxytocin (OT) families regulate salt and water homeostasis and reproduction through distinct G protein-coupled receptors. The current thinking is that there are four neurohypophysial hormone r
Autor:
Kouhei Matsuda, Minoru Uchiyama, Motoki Kamijo, Ki Sung Kang, Eri Yokobori, Morio Azuma, R. Nishiguchi
Publikováno v:
Journal of Neuroendocrinology. 24:766-773
Neuropeptide Y (NPY) is a potent orexigenic neuropeptide implicated in feeding regulation in mammals. However, except for the case of the goldfish, the involvement of NPY in the feeding behaviour of teleost fish has not well been studied. Therefore,
Autor:
Yoshitake Furuta, Makiko Yamada, Nobuhisa Masuda, Minoru Uchiyama, Koichi Yabe, Shin-ichi Inoue, Tsuneo Deguchi
Publikováno v:
Open Forum Infectious Diseases
Background Clostridium difficile infection (CDI) is the most common cause of diarrhea in hospitals. The only available intravenous (IV) therapy for CDI is metronidazole, which showed only a 52.4% cure rate in a prospective observational study. DS1196
Autor:
Sakae Kikuyama, Kazumasa Hashimoto, Noriaki Morimoto, Kouhei Matsuda, Minoru Uchiyama, Hiroshi Mochida, Reiko Okada
Publikováno v:
Peptides. 32:1872-1875
Corticotropin-releasing factor (CRF) and CRF-related peptides exert hypophysiotropic and anorexigenic effects in mammals and teleost fish. In anuran amphibians, CRF acts as a potent stimulator of thyrotropin release from the pituitary. According to o