Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Minoru Tsuchitani"'
Morphological analyses of nephrin expression in progressive glomerulonephropathy of common marmosets
Publikováno v:
Journal of Toxicologic Pathology
In this study, we focused on nephrin, one of the key molecules within the slit diaphragm of podocytes, as although there have been reports on its expression in humans and rats, their presence in common marmosets has not been reported. We investigated
Publikováno v:
Journal of Applied Toxicology. 41:1304-1315
Itai-itai (Japanese, "It hurts! It hurts!") disease (IID), a form of osteomalacia, can be induced in ovariectomized rats by long-term administration of cadmium (Cd). This IID rat model shows severe anemia, severe nephropathy, and osteomalacia accompa
Autor:
Takeshi Kanno, Yuki Tomonari, Minoru Tsuchitani, Naoaki Yamada, Junko Sato, Tetsuro Kurotaki, Takuya Doi
Publikováno v:
Toxicologic Pathology. 48:649-655
Previously, we investigated the higher incidence of hyperplastic lesions and thymomas and histopathological resemblance of cortex–medullary structures between thymomas and normal thymuses in Wistar Hannover (WH) rats. Thymomas had pale-staining cel
Publikováno v:
Journal of Toxicologic Pathology
A mass was detected in the right tympanic cavity of a 15-week-old male Crl:CD(SD) rat. Histological examination revealed papillary or tubular proliferations of epithelial cells including ciliated cells that produce mucus and have an abundant eosinoph
Publikováno v:
Journal of Toxicologic Pathology
We encountered hematolymphoid neoplastic lesions in the form of many nodules in the spleen and liver in a 110-week-old male Wistar Hannover rat (Crl:WI (Han)). The lesions contained atypical proliferative cells, eosinophils, lymphocytes, and macropha
Publikováno v:
Toxicologic Pathology. 47:129-137
Thymomas occur prevalently in aged Wistar Hannover (WH) rats, along with hyperplastic lesions that cannot be categorized as thymomas. We compared the histological features of hyperplastic lesions and thymomas in WH rats, the incidences of these lesio
Autor:
Junko Sato, Minoru Tsuchitani, Yoshiyasu Kobayashi, Yuki Tomonari, Takeshi Kanno, Tetsuro Kurotaki, Naoaki Yamada
Publikováno v:
The Journal of Veterinary Medical Science
In a previous study, we showed that 2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNPase) expression is induced in different temporal patterns in the cerebrum, cerebellum and medulla oblongata of hexachlorophene (HCP) and cuprizone (CPZ) treated rat
Autor:
Junko Sato, Takuya Doi, Kaoru Inoue, Miwa Takahashi, Midori Yoshida, Yumi Wako, Minoru Tsuchitani, Yuki Tomonari, Shino Kumabe
Publikováno v:
Journal of Toxicologic Pathology
To clarify the histopathological characteristics of rat endometrial stromal sarcoma (ESS), we morphologically reviewed 12 malignant uterine tumors protruding into the lumen in previous rat carcinogenicity studies. The 12 cases were classified into th
Autor:
Junko Sato, Nanako Hashimoto, Minoru Tsuchitani, Kinji Shirota, Naoaki Yamada, Junichi Kamiie, Takeshi Inoue, Takuya Doi
Publikováno v:
Veterinary Pathology. 55:173-176
The authors previously investigated progressive glomerulonephropathy in 2- to 11-year-old common marmosets and characterized age-related changes of the renal glomeruli and development of tubulointerstitial lesions. In this study, immunoglobulin depos
Publikováno v:
Journal of Toxicologic Pathology
A 20-week-old male Sprague Dawley rat noted with decreased body weight, dyspnea, and anorexia beginning 2 days before death was necropsied in the recovery period of a sub-chronic toxicity study. The heart was severely enlarged (30 × 20 × 20 mm), 3