Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Minoru Tamiya"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126921 (2015)
Among proteins utilized as sweeteners, neoculin and miraculin are taste-modifying proteins that exhibit pH-dependent sweetness. Several experiments on neoculin have shown that His11 of neoculin is responsible for pH dependence. We investigated the mo
Externí odkaz:
https://doaj.org/article/a843986fab8d45c3a18de7c27df87407
Autor:
Kenichi Nomura, Satoshi Hashimoto, Ryuuichi Takeyama, Minoru Tamiya, Tatsuya Kato, Terushige Muraoka, Mirai Kage, Keiji Nii, Kenichiro Kotake, Satomi Iida, Takashi Emura, Mikimasa Tanada, Hitoshi Iikura
Publikováno v:
Journal of Medicinal Chemistry. 65:13401-13412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe400c8af36a5ed8861dfb32efb00659
https://doi.org/10.1021/acs.jmedchem.2c01296
https://doi.org/10.1021/acs.jmedchem.2c01296
Autor:
Kazuya Ishizawa, Nobuhisa Isaka, Minoru Tamiya, Atsushi Hasegawa, Takaaki Kitazawa, Mayu Ikeda, Masaji Ishiguro, Saki Kawada
Publikováno v:
Bulletin of the Chemical Society of Japan. 92:1474-1494
We describe here the syntheses of velutinol A (1) and the structurally similar compounds 2–4 sharing a highly oxygenated seco-pregnane cage-like structure. The synthesis of velutinol A (1, 15,16-se...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e591abf493375dfd973631681e551db8
https://doi.org/10.1246/bcsj.20190048
https://doi.org/10.1246/bcsj.20190048
Autor:
Minoru Tamiya, Masaji Ishiguro, Kana Saida–Tamiya, Takaaki Kitazawa, Nobuhisa Isaka, Ayako Matsukawa, Genki Sekiya, Kohichi Kawahara, Kazunori Isobe, Akihiko Komuro
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(11)
A study of the structural requirements of cholic acid derivatives as liver X receptor (LXR) ligands was performed. A model of cholenamide derivative 1 complexed with LXR showed that the C24 carbonyl oxygen forms a hydrogen bond with His435 located cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af08eb887e463b78aa5bfb5c371d398f
https://pubmed.ncbi.nlm.nih.gov/30952591
https://pubmed.ncbi.nlm.nih.gov/30952591
Publikováno v:
European Journal of Organic Chemistry. 2012:665-668
A concise route to the bradykinin B1 receptor antagonist velutinol A, a natural product isolated from the rhizomatous of mandevilla velutina (Apocynaceae), has been developed. This synthesis features the highly regioselective construction of Δ 14 si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06398d25a24cd1f74eb2b07d563cc4c8
https://doi.org/10.1002/ejoc.201101728
https://doi.org/10.1002/ejoc.201101728
Publikováno v:
Chemistry Letters. 43:1704-1706
2,6-Dideoxy-3-O-methylpyranosylillustrol (3) was stereoselectively synthesized through the oxidative construction of a cage-like DEF ring moiety and stereoselective glycosylation of a 2,6-dideoxysa...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34059aebef44471e447979c9ac5c57fd
https://doi.org/10.1246/cl.140632
https://doi.org/10.1246/cl.140632
Autor:
Louis Morency, Vilnis Liepins, Daniel Laurich, Jaques-Alexis Funel, Laure C. Bouchez, Minoru Tamiya, Florent Beaufils, Ryan Gilmour, François-Hugues Porée, Alois Fürstner
Publikováno v:
Chemistry - A European Journal. 15:3983-4010
Nature is a pretty unselective "chemist" when it comes to making the highly cytotoxic amphidinolide macrolides of the B/G/H series. To date, 16 different such compounds have been isolated, all of which could now be approached by a highly convergent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0324ec47ffeaa3f6116712720e5375
https://doi.org/10.1002/chem.200802067
https://doi.org/10.1002/chem.200802067
Publikováno v:
Synlett. 2007:0780-0784
Stereoselective access to 9-alkyl-10-hydroxy-9,10-dihydrophenanthrenes has been developed via the samarium(II) iodide mediated reductive cyclization of an ene-aldehyde appended to a biphenyl scaffold.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33a1abd68d2f1cfc18c9fefaaf4fd90
https://doi.org/10.1055/s-2007-970771
https://doi.org/10.1055/s-2007-970771
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126921 (2015)
PLoS ONE
PLoS ONE
Among proteins utilized as sweeteners, neoculin and miraculin are taste-modifying proteins that exhibit pH-dependent sweetness. Several experiments on neoculin have shown that His11 of neoculin is responsible for pH dependence. We investigated the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24afccfd0a7f912f3d02f015cf31d29f
http://europepmc.org/articles/PMC4444330?pdf=render
http://europepmc.org/articles/PMC4444330?pdf=render
Publikováno v:
ChemInform. 42
Title reaction of cyclic silylenol ethers derived from dehydroepiandrosterone, e.g. (I), affords α,β-unsaturated lactones like (III).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1af8d9bf16cb968800c9caf2191b84f
https://doi.org/10.1002/chin.201131175
https://doi.org/10.1002/chin.201131175