Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Minoru Shigekawa"'
Autor:
Katsuhiko Sato, Hayato Hikita, Minoru Shigekawa, Kazumasa Soma, Ryohei Yamauchi, Jihyun Sung, Seiya Kato, Yoichi Sasaki, Shinnosuke Kudo, Kenji Fukumoto, Kumiko Shirai, Kazuhiro Murai, Yuki Tahata, Teppei Yoshioka, Akira Nishio, Yoshinobu Saito, Takahiro Kodama, Yutaka Sasaki, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Obesity is a risk factor for pancreatic cancer development, partly due to the tissue environment of metabolic disorder-related inflammation. We aimed to detect a tissue environment marker triggered by obesity-related metabolic disorders rela
Externí odkaz:
https://doaj.org/article/8f613e2378b94d819f4f6c55fe410ea1
Autor:
Jun Murata, Minoru Shigekawa, Shuji Ishii, Takahiro Suda, Kenji Ikezawa, Motohiro Hirao, Kengo Matsumoto, Tadashi Kegasawa, Kiyoshi Iwahashi, Sadaharu Iio, Fumihiko Nakanishi, Shoichi Nakazuru, Yuichi Yoshida, Takuo Yamai, Katsuhiko Sato, Teppei Yoshioka, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Objective Adequate biliary decompression is important in treating bile leaks, and endoscopic transpapillary drainage is widely used for this purpose. As an indicator to evaluate the usefulness of endoscopic drainage for postoperative biliary
Externí odkaz:
https://doaj.org/article/689c4068e8cf47ff94ce1a5c3f3e84d2
Autor:
Junya Okabe, Takahiro Kodama, Yu Sato, Satoshi Shigeno, Takayuki Matsumae, Kazuma Daiku, Katsuhiko Sato, Teppei Yoshioka, Minoru Shigekawa, Masaya Higashiguchi, Shogo Kobayashi, Hayato Hikita, Tomohide Tatsumi, Toru Okamoto, Takashi Satoh, Hidetoshi Eguchi, Shizuo Akira, Tetsuo Takehara
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-15 (2023)
Abstract Background Pancreatitis is known to be an important risk factor for pancreatic ductal adenocarcinoma (PDAC). However, the exact molecular mechanisms of how inflammation promotes PDAC are still not fully understood. Regnase-1, an endoribonucl
Externí odkaz:
https://doaj.org/article/068d42afa9724d5e91d235e206d129dd
Autor:
Yuki Makino, Hayato Hikita, Seiya Kato, Masaya Sugiyama, Minoru Shigekawa, Tatsuya Sakamoto, Yoichi Sasaki, Kazuhiro Murai, Sadatsugu Sakane, Takahiro Kodama, Ryotaro Sakamori, Shogo Kobayashi, Hidetoshi Eguchi, Nobuyuki Takemura, Norihiro Kokudo, Hideki Yokoi, Masashi Mukoyama, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 1, Pp 99-119 (2023)
Background & Aims: Signal transducer and activator of transcription 3 (STAT3) is known as a pro-oncogenic transcription factor. Regarding liver carcinogenesis, however, it remains controversial whether activated STAT3 is pro- or anti-tumorigenic. Thi
Externí odkaz:
https://doaj.org/article/1eb3d8992b60484ab06969f6bb67f258
Autor:
Katsuhiko Sato, Minoru Shigekawa, Kazuhiro Kozumi, Junya Okabe, Yu Sato, Takeshi Tamura, Teppei Yoshioka, Ryotaro Sakamori, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Takehiro Noda, Hidenori Takahashi, Shogo Kobayashi, Hidetoshi Eguchi, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
DEN Open, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract Objectives Perihilar cholangiocarcinoma (PCC) is a complex disorder involving the hepatic hilum. Multiple endoscopic retrograde cholangiopancreatography sessions are necessary for diagnosis and treatment with underlying cholangitis risk. Our
Externí odkaz:
https://doaj.org/article/5af7df7195fc46638fbb71370fd507a2
Autor:
Kenji Ikezawa, Minoru Shigekawa, Kaoruko Sengoku, Teppei Yoshioka, Ryotaro Sakamori, Yasushi Sakata, Tetsuo Takehara
Publikováno v:
Clinical Case Reports, Vol 7, Iss 7, Pp 1327-1330 (2019)
Abstract Linear endoscopic ultrasound (L‐EUS) is mainly performed to assess pancreaticobiliary and mediastinal diseases. In this report, transesophageal observation with L‐EUS revealed an LAA thrombus that was not detected by transthoracic echoca
Externí odkaz:
https://doaj.org/article/2cb832a754244029bd9a0c374d990e12
Autor:
Katsuhiko Sato, Hayato Hikita, Yuta Myojin, Kenji Fukumoto, Kazuhiro Murai, Sadatsugu Sakane, Takeshi Tamura, Takuo Yamai, Yasutoshi Nozaki, Teppei Yoshioka, Takahiro Kodama, Minoru Shigekawa, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235573 (2020)
Diabetes mellitus is a well-known risk factor for pancreatic cancer. We focused on hyperglycemia, a main feature of diabetes mellitus, and uncovered its effect on precancerous pancreatic intraepithelial neoplasia (PanIN) progression. In vivo inductio
Externí odkaz:
https://doaj.org/article/941ca0b579394a04b93f4a9ca994bf22
Autor:
Takahiro Suda, Tomohide Tatsumi, Akira Nishio, Tadashi Kegasawa, Teppei Yoshioka, Ryoko Yamada, Kunimaro Furuta, Takahiro Kodama, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Takasuke Fukuhara, Yoshiharu Matsuura, Tetsuo Takehara
Publikováno v:
Hepatology Communications, Vol 2, Iss 10, Pp 1247-1258 (2018)
Natural killer cells (NK cells) play an essential role in the immunological mechanism underlying chronic hepatitis C (CHC). Impairment of NK cell function facilitates persistent infection with hepatitis C virus (HCV) and hepatocellular carcinogenesis
Externí odkaz:
https://doaj.org/article/65d403062b09423f9034ffca652a172f
Autor:
Kenji Ikezawa, Hayato Hikita, Minoru Shigekawa, Kiyoshi Iwahashi, Hidetoshi Eguchi, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 1, Pp 185-200.e1 (2017)
Background & Aims: Bcl-xL, an anti-apoptotic Bcl-2 family protein, is overexpressed in 90% of pancreatic ductal adenocarcinoma (PDAC) cases. However, Bcl-xL expression in pancreatic intraepithelial neoplasias (PanINs) and its significance in PDAC car
Externí odkaz:
https://doaj.org/article/70d5f444453743f3b47188e6498e4a2c
Autor:
Teppei Yoshioka, Tomohide Tatsumi, Takuya Miyagi, Kaori Mukai, Kumiko Nishio, Akira Nishio, Yoshinobu Yokoyama, Takahiro Suda, Tadashi Kegasawa, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Tetsuo Takehara
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174103 (2017)
BACKGROUND AND AIM:Natural Killer (NK) cells are involved in the control of viral infection. However, the role of NK cells in chronic hepatitis B (CHB) remains unclear. This study investigated the frequencies and roles of NK cells in CHB, with a focu
Externí odkaz:
https://doaj.org/article/d39541dafade49e89aedadf49e58a3ae