Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Minoru Kumai"'
Autor:
Kazuto Yamazaki, Kenji Kubara, Satoko Ishii, Peng Li, Ryo Dairiki, Taro Hihara, Yuta Ishizuka, Yukina Izumi, Minoru Kumai, Tsutomu Kamisako, Hiroyoshi Ishizaki, Hideyuki Sato, Hideki Masaki, Naoaki Mizuno, Kaoru Mitsuhashi, Masashi Ito, Sanae Hamanaka, Tomoyuki Yamaguchi, Motoo Watanabe, Fumihiro Sugiyama, Hiromitsu Nakauchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Blastocyst complementation is an intriguing way of generating humanized animals for organ preparation in regenerative medicine and establishing novel models for drug development. Confirming that complemented organs and cells work normally in
Externí odkaz:
https://doaj.org/article/83f9324b5cc14be682f2858dae6bd952
Autor:
Kazuto Yamazaki, Kenji Kubara, Satoko Ishii, Peng Li, Ryo Dairiki, Taro Hihara, Yuta Ishizuka, Yukina Izumi, Minoru Kumai, Tsutomu Kamisako, Hiroyoshi Ishizaki, Hideyuki Sato, Hideki Masaki, Naoaki Mizuno, Kaoru Mitsuhashi, Masashi Ito, Sanae Hamanaka, Tomoyuki Yamaguchi, Motoo Watanabe, Fumihiro Sugiyama, Hiromitsu Nakauchi
Publikováno v:
Scientific reports. 12(1)
Blastocyst complementation is an intriguing way of generating humanized animals for organ preparation in regenerative medicine and establishing novel models for drug development. Confirming that complemented organs and cells work normally in chimeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0518afe9d89535b1ba93b38d095dca8b
https://pubmed.ncbi.nlm.nih.gov/35217706
https://pubmed.ncbi.nlm.nih.gov/35217706
Autor:
Miyuki Nishimura, Masayoshi Ohkuro, Tsutomu Kamisako, Akiko Hamaguchi, Kana Hoshino-Negishi, Fumihiro Sugiyama, Minoru Kumai, Jungo Kakuta, Toshio Imai, Nobuyuki Yasuda, Wataru Ikeda, Yoko Ida, Tomoya Nakatani, Naoto Ishii, Yoshikazu Kuboi
Publikováno v:
Arthritis & Rheumatology. 71:222-231
Objective To elucidate the role of the fractalkine (FKN)/CX3 CR1 pathway in joint destruction in rheumatoid arthritis. Methods We examined the effect of treatment with anti-mouse FKN (anti-mFKN) monoclonal antibody (mAb) on joint destruction and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212b031dcc1cf1e787320b2995e8f1a3
https://doi.org/10.1002/art.40688
https://doi.org/10.1002/art.40688
Publikováno v:
Developmental Biology. 388:68-80
Purkinje cells (PCs) provide the primary output from the cerebellar cortex, which controls movement and posture, and loss of PCs causes severe cerebellar dysfunction. The mechanisms underlying cell fate determination and early differentiation of PC r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53c8e95252e8891f9b7717823fe4d78
https://doi.org/10.1016/j.ydbio.2014.01.016
https://doi.org/10.1016/j.ydbio.2014.01.016
Publikováno v:
Development. 137:1897-1906
Floor plate (FP) cells, the ventral midline cells of the developing neural tube, have long been thought to be non-neurogenic organizer cells that control neuronal patterning and axonal guidance. Recent studies have revealed that mesencephalic FP (mes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019ac133bb54c25eed5919045d76b94d
https://doi.org/10.1242/dev.042572
https://doi.org/10.1242/dev.042572
Publikováno v:
Developmental Biology. 339(1):101-113
Mesencephalic dopaminergic (mesDA) neurons control movement and behavior, and their loss causes severe neurological disorders, such as Parkinson's disease. Recent studies have revealed that mesDA neurons originate from mesencephalic floor plate (FP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1158338ec2b29163655fcd11fe236c90
Autor:
Keiko Muguruma, Minoru Kumai, Takeshi Inoue, Eri Mizuhara, Yasuko Minaki, Yoshiki Sasai, Yuichi Ono, Tomoya Nakatani
Publikováno v:
Developmental Biology. 338(2):202-214
GABAergic Purkinje cells (PCs) provide the primary output from the cerebellar cortex, which controls movement and posture. Although the mechanisms of PC differentiation have been well studied, the precise origin and initial specification mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f988547424cccab75fd7817097079b2
Autor:
Yuichi Ono, Jun Takahashi, Yoko Inoue, Yoshimasa Sakamoto, Akiko Hamaguchi, Hideki Hayashi, Miyuki Nishimura, Tomoya Nakatani, Eri Mizuhara, Toshio Imai, Yasuko Minaki, Minoru Kumai
Publikováno v:
Development. 134:3213-3225
Directed differentiation and purification of mesencephalic dopaminergic(mesDA) neurons from stem cells are crucial issues for realizing safe and efficient cell transplantation therapies for Parkinson's disease. Although recent studies have identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b47cb82a17c9df0ba0219eb9ded725
https://doi.org/10.1242/dev.02879
https://doi.org/10.1242/dev.02879
Autor:
Mayumi Yamada, Kenneth Campbell, Christopher V.E. Wright, Kazuhiro Ikenaka, Shin'ichi Ishiwata, Takayoshi Inoue, Yukiko U. Inoue, Shinichiro Taya, Tomoyuki Fujiyama, Tomoya Nakatani, Norihisa Masuyama, Yuichi Ono, Yoshiya Kawaguchi, Satoshi Miyashita, Mark A. Magnuson, Hirohide Takebayashi, Yasuko Minaki, Akiko Hamaguchi, Heather Chapman, Mikio Hoshino, Minoru Kumai, Yusuke Seto
In the cerebellum, all GABAergic neurons are generated from the Ptf1a-expressing ventricular zone (Ptf1a domain). However, the machinery to produce different types of GABAergic neurons remains elusive. Here we show temporal regulation of distinct GAB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ac62f53e0955a704b9dd22c523fd10
https://europepmc.org/articles/PMC5669625/
https://europepmc.org/articles/PMC5669625/
Publikováno v:
Development (Cambridge, England). 134(15)
The mechanism underlying the determination of neurotransmitter phenotype in the developing mesencephalon, particularly GABAergic versus glutamatergic fate, remains largely unknown. Here, we show in mice that the basic helix-loop-helix transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba08bfa79d614842dfe28c242759ea9
https://pubmed.ncbi.nlm.nih.gov/17611227
https://pubmed.ncbi.nlm.nih.gov/17611227