Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Minoru Iwata"'
Autor:
Tomohiko Asada, Minoru Iwata, Shigeru Matsuzaki, Hiroshi Hamakawa, Satoru Sengan, Toshifumi Noguchi, Kazushi Daimon, Naoki Matsumura, Morikazu Shibasaki, Tetsushi Tsujimoto, Ken Ooi, Hidenao Fukuyama
Publikováno v:
Journal of Clinical and Translational Endocrinology Case Reports, Vol 23, Iss , Pp 100107- (2022)
We present the case of a 55-year-old female patient with alcohol-related liver damage who presented with hypercalcemia and hyperphosphatemia but also showed severe paradoxical reduction in serum 25-OH vitamin D levels. The serum levels of 1, 25-(OH)
Externí odkaz:
https://doaj.org/article/89368d239bed463b9ac6a4724bad1ee2
Autor:
Minoru Iwata, Yutaka Kamura, Hisae Honoki, Kaori Kobayashi, Manabu Ishiki, Kunimasa Yagi, Yasuo Fukushima, Atsuko Takano, Hiromi Kato, Shihou Murakami, Kiyohiro Higuchi, Chikaaki Kobashi, Kazuhito Fukuda, Yukiko Koshimizu, Kazuyuki Tobe
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 3, Pp 564-572 (2020)
Abstract Aims/Introduction The objective of the present study was to clarify the association of the type and number of first‐degree family history of diabetes (FHD) with the clinical characteristics, especially with residual β‐cell function, in
Externí odkaz:
https://doaj.org/article/a1720d67a2264891be24049d604b4eaf
Autor:
Minako Imamura, Atsushi Takahashi, Toshimasa Yamauchi, Kazuo Hara, Kazuki Yasuda, Niels Grarup, Wei Zhao, Xu Wang, Alicia Huerta-Chagoya, Cheng Hu, Sanghoon Moon, Jirong Long, Soo Heon Kwak, Asif Rasheed, Richa Saxena, Ronald C. W. Ma, Yukinori Okada, Minoru Iwata, Jun Hosoe, Nobuhiro Shojima, Minaka Iwasaki, Hayato Fujita, Ken Suzuki, John Danesh, Torben Jørgensen, Marit E. Jørgensen, Daniel R. Witte, Ivan Brandslund, Cramer Christensen, Torben Hansen, Josep M. Mercader, Jason Flannick, Hortensia Moreno-Macías, Noël P. Burtt, Rong Zhang, Young Jin Kim, Wei Zheng, Jai Rup Singh, Claudia H. T. Tam, Hiroshi Hirose, Hiroshi Maegawa, Chikako Ito, Kohei Kaku, Hirotaka Watada, Yasushi Tanaka, Kazuyuki Tobe, Ryuzo Kawamori, Michiaki Kubo, Yoon Shin Cho, Juliana C. N. Chan, Dharambir Sanghera, Philippe Frossard, Kyong Soo Park, Xiao-Ou Shu, Bong-Jo Kim, Jose C. Florez, Teresa Tusié-Luna, Weiping Jia, E Shyong Tai, Oluf Pedersen, Danish Saleheen, Shiro Maeda, Takashi Kadowaki
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Here, Imamuraet al. conduct meta-analysis of genome-wide association studies to identify novel susceptibility loci for type 2 diabetes (T2D) in the Japanese population. By doing so, this study shows that both ethnicity-specific and ethnically-shared
Externí odkaz:
https://doaj.org/article/389e503091f247e28b5236cff3387f83
Autor:
Minoru Iwata, Kazuo Hara, Yutaka Kamura, Hisae Honoki, Shiho Fujisaka, Manabu Ishiki, Isao Usui, Kunimasa Yagi, Yasuo Fukushima, Atsuko Takano, Hiromi Kato, Shihou Murakami, Kiyohiro Higuchi, Chikaaki Kobashi, Kazuhito Fukuda, Yukiko Koshimizu, Kazuyuki Tobe
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192609 (2018)
Among the three adiponectin isoforms, a lower ratio of high molecular weight (HMW) adiponectin to total adiponectin (TA) is well known to cause insulin resistance and type 2 diabetes (T2D). However, how the levels of other adiponectin isoforms, such
Externí odkaz:
https://doaj.org/article/4a48fa4938c246759ae6aeb1ba5d4cec
Autor:
Ren Matsuba, Minako Imamura, Yasushi Tanaka, Minoru Iwata, Hiroshi Hirose, Kohei Kaku, Hiroshi Maegawa, Hirotaka Watada, Kazuyuki Tobe, Atsunori Kashiwagi, Ryuzo Kawamori, Shiro Maeda
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154093 (2016)
AIM:We performed a replication study in a Japanese population to evaluate the association between type 2 diabetes and six susceptibility loci (TMEM154, SSR1, FAF1, POU5F1, ARL15, and MPHOSPH9) originally identified by a transethnic meta-analysis of g
Externí odkaz:
https://doaj.org/article/c8a792c2be3b4262bdb742cd7aac707e
Autor:
Yutaka Kamura, Minoru Iwata, Shiro Maeda, Satomi Shinmura, Yukiko Koshimizu, Hisae Honoki, Kazuhito Fukuda, Manabu Ishiki, Isao Usui, Yasuo Fukushima, Atsuko Takano, Hiromi Kato, Shihou Murakami, Kiyohiro Higuchi, Chikaaki Kobashi, Kazuyuki Tobe
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165523 (2016)
Several studies have demonstrated that polymorphisms within the fat-mass and obesity-associated gene (FTO) are associated with type 2 diabetes (T2D). However, whether the effects of the FTO locus on T2D susceptibility are independent of fat-mass incr
Externí odkaz:
https://doaj.org/article/41077e01667841539abdaeaf332fe035
Autor:
Ren Matsuba, Kensuke Sakai, Minako Imamura, Yasushi Tanaka, Minoru Iwata, Hiroshi Hirose, Kohei Kaku, Hiroshi Maegawa, Hirotaka Watada, Kazuyuki Tobe, Atsunori Kashiwagi, Ryuzo Kawamori, Shiro Maeda
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126363 (2015)
We performed a replication study in a Japanese population to evaluate the association between type 2 diabetes and 7 susceptibility loci originally identified by European genome-wide association study (GWAS) in 2012: ZMIZ1, KLHDC5, TLE1, ANKRD55, CILP
Externí odkaz:
https://doaj.org/article/5d8f628bad9340399a87a3c6dcb6a961
Autor:
Kensuke Sakai, Minako Imamura, Yasushi Tanaka, Minoru Iwata, Hiroshi Hirose, Kohei Kaku, Hiroshi Maegawa, Hirotaka Watada, Kazuyuki Tobe, Atsunori Kashiwagi, Ryuzo Kawamori, Shiro Maeda
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76317 (2013)
AimsEast Asian genome-wide association studies (GWAS) for type 2 diabetes identified 8 loci with genome-wide significance, and 2 loci with a borderline association. However, the associations of these loci except MAEA locus with type 2 diabetes have n
Externí odkaz:
https://doaj.org/article/a731377e7e1c4fa48c5d24b1708539d2
Autor:
Hisashi Fukuda, Minako Imamura, Yasushi Tanaka, Minoru Iwata, Hiroshi Hirose, Kohei Kaku, Hiroshi Maegawa, Hirotaka Watada, Kazuyuki Tobe, Atsunori Kashiwagi, Ryuzo Kawamori, Shiro Maeda
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46263 (2012)
The DUSP9 locus on chromosome X was identified as a susceptibility locus for type 2 diabetes in a meta-analysis of European genome-wide association studies (GWAS), and GWAS in South Asian populations identified 6 additional single nucleotide polymorp
Externí odkaz:
https://doaj.org/article/e206e42b76da4787a7ce47e0f4e2e5d3
Autor:
Toshihiko Ohshige, Minoru Iwata, Shintaro Omori, Yasushi Tanaka, Hiroshi Hirose, Kohei Kaku, Hiroshi Maegawa, Hirotaka Watada, Atsunori Kashiwagi, Ryuzo Kawamori, Kazuyuki Tobe, Takashi Kadowaki, Yusuke Nakamura, Shiro Maeda
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26911 (2011)
BackgroundSeveral novel susceptibility loci for type 2 diabetes have been identified through genome-wide association studies (GWAS) for type 2 diabetes or quantitative traits related to glucose metabolism in European populations. To investigate the a
Externí odkaz:
https://doaj.org/article/c578f8b354c64260aa5491ac50f5f02d