Zobrazeno 1 - 10 of 54 pro vyhledávání: '"Minoru Hirata"'
1
Sequence determination of phosphorothioated oligonucleotides using MALDI-TOF mass spectrometry for controlling gene doping in equestrian sports
Autor: Minoru Hirata, Shun-ichi Nagata, Mio Kikuchi, Kotono Nakamura, Aoi Ohnuma, Kei-ichi Hirota, Masaki Takasu, Hironaga Kakoi, Ho-Geun Kwak, Takashi Nirasawa, Kanichi Kusano, Taichiro Ishige, Hideaki Ishii, Teruaki Tozaki
Publikováno v: Drug testing and analysisREFERENCES. 14(1)
In human and equestrian sporting events, one method of gene doping is the illegal use of therapeutic oligonucleotides to alter gene expression. In this study, we aimed to identify therapeutic oligonucleotides via sequencing using matrix-assisted lase
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e53bfbf371f405b067787bc67d208c
https://pubmed.ncbi.nlm.nih.gov/34418319
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3
Coronary vasospastic action of thromboxane A2 in isolated, working guinea pig hearts
Autor: Shintaro Kikuchi, Kohei Nishikawa, Hiroshi Fukui, Zen-ichi Terashita, Minoru Hirata
Publikováno v: European Journal of Pharmacology. 53:49-56
The effects of thromboxane A 2 (TXA 2 ) on isolated, working guinea pig heart and left ventricular papillary muscle preparations were investigated. TXA 2 was generated by the enzymatic conversion of prostaglandin H 2 (PGH 2 ) with indomethacin-treate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706e65e2cf3db28f95dc2e6b0f246730
https://doi.org/10.1016/0014-2999(78)90266-2
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4
Coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion in anaesthetised dogs
Autor: Kohei Nishikawa, Shuji Fujiwara, Zen-ichi Terashita, Minoru Hirata, Masao Tanabe, Noriko Goto, Norio Shimamoto
Publikováno v: Cardiovascular Research. 16:99-106
Attempts were made to demonstrate release of vasoactive substances from the heart during coronary occlusion (for 60 min) and reperfusion (for 60 min), and to clarify the pathophysiological significance of them. Vasoactive substances were detected by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5abaee29f315a2330a639c6e45b4ec
https://doi.org/10.1093/cvr/16.2.99
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6
Synthesis and .BETA.-adrenergic blocking activity of 2-(N-substituted amino)-1,2,3,4-tetrahydronaphthalen-1-ol derivatives
Autor: Yoshikazu Oka, Akio Miyake, Norio Tada, Katsumi Itoh, Minoru Hirata
Publikováno v: Chemical and Pharmaceutical Bulletin. 32:130-151
In a search for a new structural type of β-adrenergic antagonist. a series of trans-2-(N-substituted amino)-1, 2, 3, 4-tetrahydronaphthalen-1-ol derivatives (3-36) was synthesized in several steps from 3, 4-dihydro-1 (2H)-naphthalenone (37) having a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e749f6d16e6b460cdf0007a8cf757bf9
https://doi.org/10.1248/cpb.32.130
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7
EFFECTS OF A 2-SUBSTITUTED ADENOSINE DERIVATIVE, 2-(P-METHOXYPHENYL)-ADENOSINE (CV-1674) ON CORONARY AND CARDIOHEMODYNAMICS, AND MYOCARDIAL ENERGETICS
Autor: Katsuyoshi Kawazoe, Minoru Hirata, Masao Tanabe, Kenzo Kikuchi
Publikováno v: Japanese Journal of Pharmacology. 27:689-700
In dogs, intracoronary doses of CV-1674, adenosine ( ADS) and 2-Cl-ADS for doubling coronary flow were estimated as 5.0, 2.0 and 0.4 microgram/dog, and i.v. doses 31, 71 and 2.5 microgram/kg, respectively. ADS and 2-Cl-ADS decreased, while CV-1674 in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4864009e16833e7beb4e05cf3d4e1e1b
https://doi.org/10.1254/jjp.27.689
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8
Synthesis and biological activities of 3-aminomethyl-1,2-dihydronaphthalene derivatives
Autor: Akio Miyake, Katsumi Itoh, Minoru Hirata, Yoshikazu Oka, Masao Tanabe
Publikováno v: Chemical and Pharmaceutical Bulletin. 31:2006-2015
A series of 3-aminomethyl-1, 2-dihydronaphthalene derivatives (6-22) was prepared from the corresponding 3, 4-dihydro-1 (2H)-naphthalenone derivatives (24a-q) in three steps, namely the Mannich reaction, reduction of the carbonyl group with sodium bo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4817d4ee88a38caa14d1ad40a75a3870
https://doi.org/10.1248/cpb.31.2006
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9
Inhibition of Coronary Circulatory Failure and Thromboxane A2 Release During Coronary Occlusion and Reperfusion by 2-Phenylaminoadenosine (CV-1808) in Anesthetized Dogs
Autor: Nishikawa K, Zen-ichi Terashita, Minoru Hirata, Masao Tanabe
Publikováno v: Journal of Cardiovascular Pharmacology. 6:442-448
The effects of potent coronary vasodilator, 2- phenylaminoadenosine (CV-1808), on coronary circulatory failure and thromboxane (TX) A2 release were studied during coronary occlusion (for 60 min) and subsequent reperfusion (for 60 min) in anesthetized
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e34411d5b00bf8fce938fdaa4300e31
https://doi.org/10.1097/00005344-198405000-00011
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10
Fatty Acid Metabolism in Blue Crab, Portunus trituberculatus, with Special Reference to De Novo Synthesis and Conversion
Autor: Minoru Hirata, Mitsu Kayama
Publikováno v: Journal of Japan Oil Chemists' Society. 33:426-434
Japanese blue crab, Portunus trituberculatus, contains 1.6% of lipids as whole body with particularly high content (12.3%) in hepatopancreas and approximately 1% in muscle in the wet weight basis. The lipids of various tissues consist mainly of trigl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75b5c946ef4f6f53088b4d84e45a4d01
https://doi.org/10.5650/jos1956.33.426
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