Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Minori Saitoh"'
Autor:
Minori Saitoh, Yoshiyuki Iwatsuki, Toshio Uemura, Ken-ichi Suzuki, Tomihisa Kawasaki, Toshiyuki Funatsu, Seiji Kaku
Publikováno v:
European Journal of Pharmacology. 699:40-47
The oral direct factor Xa inhibitor darexaban administered intraduodenally prevented venous thrombus formation in both rats and rabbits with no effect on bleeding. The indirect parenteral Factor Xa inhibitor fondaparinux exerted similar properties, o
Autor:
Minori Saitoh, Kazutaka Suga, Shuhei Yasuda, Keiji Miyata, Satoshi Kokubo, Seiji Kaku, Shinji Fukushima
Publikováno v:
Journal of Interferon & Cytokine Research. 23:203-207
We previously demonstrated that recombinant human interleukin-11 (rHuIL-11) induced osteoblast differentiation of C3H10T1/2 progenitor cells and also acted synergistically with recombinant human bone morphogenetic protein-2 (rHuBMP-2) in performing t
Autor:
Keiji Miyata, Kazuhiro Momose, Shuhei Yasuda, Yumiko Ogawa, Kazutaka Suga, Minori Saitoh, Katsunari Taguchi
Publikováno v:
Cytokine. 13:287-294
Recombinant human interleukin 11 (rhIL-11) has previously been shown to ameliorate thrombocytopenia in several animal models. To elucidate the mechanisms involved in rhIL-11-induced hematopoiesis, a kinetic analysis of megakaryopoiesis was performed
Autor:
Junko Maehara, Masanori Suzuki, Minori Saitoh, Toshiyuki Funatsu, Hideyuki Tanaka, Shinji Usuda
Publikováno v:
Current Therapeutic Research. 61:7-18
Objective To compare the thrombolytic activity of YM866, a modified tissue-type plasminogen activator (t-PA), with that of alteplase in dogs with induced coronary artery thrombi and rats with induced carotid artery thrombi. Background Although t-PA r
Autor:
Toshiyuki Funatsu, Tomihisa Kawasaki, Yoshiyuki Iwatsuki, Seiji Kaku, Minori Saitoh, Toshio Uemura, Ken-ichi Suzuki, Mami Suzuki
Publikováno v:
Thrombosis research. 131(5)
Here, we investigated the anticoagulant effects of darexaban in mice and human plasma in vitro, effects of darexaban in thrombosis and bleeding models in mice, and reversal effects of anti-inhibitor coagulant complex (ACC) and recombinant factor VIIa
Autor:
Kazutoshi Nozaki, Kazutaka Suga, Keiji Miyata, Minori Saitoh, Shuhei Yasuda, Shinji Fukushima, Masao Sasamata, Satoshi Kokubo
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 24(6)
Recombinant human interleukin-11 (rHuIL-11) and recombinant human bone morphogenetic protein-2 (rHuBMP-2) have been shown to act synergistically in the induction of osteoblast differentiation. To determine whether these two proteins can be used clini
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 22:S339-S341
Summary 1. The effects of barnidipine on blood flow to major organs and on renal function were investigated in anaesthetized dogs and conscious spontaneously hypertensive rats (SHR), and the results were compared with those for nicardipine, nitrendip
Publikováno v:
Arzneimittel-Forschung. 52(11)
Interleukin-11 (IL-11, CAS 145941-26-0) is a cytokine that ameliorates thrombocytopenia induced by chemotherapy. Granulocyte colony-stimulating factor (G-CSF) is frequently used clinically as an adjuvant therapy to ameliorate neutropenia. In this stu
Autor:
Hiromi Nara, Minori Saitoh, Shuhei Yasuda, Kohichiro Takahashi, Shinji Fukushima, Keiji Miyata, Kazutaka Suga
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 21(9)
Interleukin-11 (IL-11) is a pleiotropic cytokine that supports various types of hematopoietic cell growth and is involved in bone resorption. We report here the involvement of recombinant human IL-11 (rHuIL-11) in osteoblast differentiation in mouse
Autor:
Keiji Miyata, Noriyuki Yamazaki, Katsunari Taguchi, Kazuhiro Momose, Chizuko Ono, Tatsuo Suzuki, Shuhei Yasuda, Minori Saitoh, Kazutaka Suga, Osamu Takeuchi
Publikováno v:
Cancer chemotherapy and pharmacology. 49(2)
Purpose: Interleukin-11 (IL-11) is a stromal cell derived multifunctional cytokine, which plays important roles in the hematopoietic and nonhematopoietic systems. Recombinant human IL-11 (rhIL-11) is used in the treatment of chemotherapy-induced thro