Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Minori Masago"'
Autor:
Mitsuyuki Shimada, Hiroshi Miki, Kouhei Asano, Masaki Ogino, Yoshihisa Nakada, Toshihiro Yamamoto, Hiroshi Yamaguchi, Minori Masago, Norikazu Tamura, Kazuko Aoki, Koki Kato
Publikováno v:
European Journal of Pharmacology. 640:243-249
Coenzyme A (CoA):diacylglycerol acyltransferase 1 (DGAT1) is 1 of the 2 known DGAT enzymes that catalyze the final and only committed step in triacylglycerol synthesis; this enzyme is considered to be a potential therapeutic target in metabolic disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47d4c79196895bf4987370a7fa79251
https://doi.org/10.1016/j.ejphar.2010.04.050
https://doi.org/10.1016/j.ejphar.2010.04.050
Autor:
Yoshihisa Nakada, Minori Masago, Mitsuyuki Shimada, Toshihiro Yamamoto, Kouhei Asano, Kazuko Aoki, Hiroshi Miki, Norikazu Tamura, Koki Kato, Masaki Ogino
Publikováno v:
Chemical and Pharmaceutical Bulletin. 58:673-679
In a program to discover new small molecule diacylglycerol acyltransferase (DGAT)-1 inhibitors, screening of our in-house chemical library was carried out using recombinant human DGAT-1 enzyme. From this library, the lead compound 1a was identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290ff49f8f9e87b4a037af867ededf87
https://doi.org/10.1248/cpb.58.673
https://doi.org/10.1248/cpb.58.673
Autor:
Kouhei Asano, Masaki Ogino, Toshihiro Yamamoto, Mitsuyuki Shimada, Norikazu Tamura, Kazuko Aoki, Yoshihisa Nakada, Hiroshi Miki, Minori Masago, Koki Kato
Publikováno v:
ChemInform. 41
A series of novel N-(substituted hetaryl)-4-aryl-4-oxobutanamides are designed, synthesis and evaluated for their activity against DGAT-1 enzyme.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec51c8607cf998bfb16eb107dd02fa21
https://doi.org/10.1002/chin.201043129
https://doi.org/10.1002/chin.201043129