Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Minoo Rassoulzadegan"'
Autor:
Zeynep Yilmaz Sukranli, Keziban Korkmaz Bayram, Serpil Taheri, Francois Cuzin, Yusuf Ozkul, Minoo Rassoulzadegan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract We previously identified a unique genetic feature of Autism Spectrum Disorder (ASD) in human patients and established mouse models, a low to very low level of six microRNAs, miR-19a-3p, miR-361-5p, miR-3613-3p, miR-150-5p, miR-126-3p and miR
Externí odkaz:
https://doaj.org/article/f974551c620b47448dd9fc9edfebe50e
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1183 (2024)
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with a highly variable expression of phenotypes (restricted interest or activity and repetitive behavior in communication and social interactions), genes (mutation), markers (alt
Externí odkaz:
https://doaj.org/article/f502455f8e884b53a31539f6bdd839ad
Autor:
Zeynep Yilmaz Sukranli, Keziban Korkmaz Bayram, Ecmel Mehmetbeyoglu, Zuleyha Doganyigit, Feyzullah Beyaz, Elif Funda Sener, Serpil Taheri, Yusuf Ozkul, Minoo Rassoulzadegan
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 201 (2024)
Recently, we described the alteration of six miRNAs in the serum of autistic children, their fathers, mothers, siblings, and in the sperm of autistic mouse models. Studies in model organisms suggest that noncoding RNAs participate in transcriptional
Externí odkaz:
https://doaj.org/article/1184744af79549c988e597d18396455f
Autor:
Guzide Satir-Basaran, Leila Kianmehr, Ecmel Mehmetbeyoglu, Kezban Korkmaz Bayram, Mehmet Memis, Zeynep Yilmaz, Esra Tufan, Serpil Taheri, Fahrettin Kelestimur, Minoo Rassoulzadegan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
A wide range of diseases result from environmental effects, and the levels of many native transcripts are altered. The alteration of non-coding RNAs (ncRNAs) and transmission of the variation to the next generation is increasingly recognized as a mar
Externí odkaz:
https://doaj.org/article/e7481cc875fd497aab6d5136f4bd2445
Autor:
Serpil Taheri, Züleyha Karaca, Ecmel Mehmetbeyoglu, Zuhal Hamurcu, Zeynep Yilmaz, Fatma Dal, Venhar Çınar, Halil Ulutabanca, Fatih Tanriverdi, Kursad Unluhizarci, Minoo Rassoulzadegan, Fahrettin Kelestimur
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15699 (2022)
Traumatic brain injury (TBI) is a major health problem affecting millions of people worldwide and leading to death or permanent damage. TBI affects the hypothalamic–pituitary–adrenal (HPA) axis either by primary injury to the hypothalamic–hypop
Externí odkaz:
https://doaj.org/article/c4d9b10f07eb4e328e0b43a3dcca9bd3
Autor:
Ismail Kocyigit, Serpil Taheri, Cihan Uysal, Mehmet Memis, Salih Guntug Ozayturk, Gokmen Zararsiz, Minoo Rassoulzadegan
Publikováno v:
Cells, Vol 11, Iss 20, p 3300 (2022)
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of chronic kidney disease with Polycystin (PKD) 1 and 2 gene mutation. However, the intra-familial variability in symptoms further suggests a non-Mendelian contri
Externí odkaz:
https://doaj.org/article/59d91570162d4b6ba5422bad705fde20
Autor:
Ecmel Mehmetbeyoglu, Leila Kianmehr, Murat Borlu, Zeynep Yilmaz, Seyma Basar Kılıc, Hassan Rajabi-Maham, Serpil Taheri, Minoo Rassoulzadegan
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 368 (2022)
Functional long non-coding RNAs (lncRNAs) have been in the limelight in aging research because short telomeres are associated with higher levels of TERRA (Telomeric Repeat containing RNA). The genomic instability, which leads to short telomeres, is a
Externí odkaz:
https://doaj.org/article/2f3ebd4eacc84bc49abec36de4d416ce
DNA-RNA Hybrid (R-Loop): From a Unified Picture of the Mammalian Telomere to the Genome-Wide Profile
Publikováno v:
Cells, Vol 10, Iss 6, p 1556 (2021)
Local three-stranded DNA/RNA hybrid regions of genomes (R-loops) have been detected either by binding of a monoclonal antibody (DRIP assay) or by enzymatic recognition by RNaseH. Such a structure has been postulated for mouse and human telomeres, cle
Externí odkaz:
https://doaj.org/article/469dd9c901f6413e875b9d72342b69f7
Autor:
Nicole Wagner, Marina Ninkov, Ana Vukolic, Günseli Cubukcuoglu Deniz, Minoo Rassoulzadegan, Jean-François Michiels, Kay-Dietrich Wagner
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4346 (2021)
The Wilms’ tumor suppressor Wt1 is involved in multiple developmental processes and adult tissue homeostasis. The first phenotypes recognized in Wt1 knockout mice were developmental cardiac and kidney defects. Wt1 expression in the heart has been d
Externí odkaz:
https://doaj.org/article/61f7616acb55428e92456e4cdb8c7e44
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172780 (2017)
The hereditary transmission of a phenotype independent from DNA sequence implies epigenetic effects. Paramutation is a heritable epigenetic phenomenon observed in plants and animals. To investigate paramutation in Drosophila, we used the P{ry+t7.2 =
Externí odkaz:
https://doaj.org/article/8984eb791acb49d4b10847ab9758db32