Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Minoo J. Moghaddam"'
Autor:
Sohel M Julovi, Aiqun Xue, Thao N Thanh LE, Anthony J Gill, Jerikho C Bulanadi, Mili Patel, Lynne J Waddington, Kerry-Anne Rye, Minoo J Moghaddam, Ross C Smith
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151475 (2016)
BackgroundApolipoprotein A-II (ApoA-II) is down regulated in the sera of pancreatic ductal adenocarcinoma (PDAC) patients, which may be due to increase utilization of high density lipoprotein (HDL) lipid by pancreatic cancer tissue. This study examin
Externí odkaz:
https://doaj.org/article/c64a44673ba34d4ea422a8258251286d
Autor:
Lynne J. Waddington, Gregory Coia, Judith A. Scoble, Mioko Hirabayashi, Liliana de Campo, Calum J. Drummond, Penny A. Bean, Minoo J. Moghaddam
Publikováno v:
Biomaterials science. 2(6)
Engineering biocompatible and physiologically stable nanoscaled therapeutics and imaging agents with the ability to target tumor tissue is a key challenge for the advancement of cancer therapeutics and diagnostic imaging. Here, we present chelating a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c7cbca26d3f8f21193ff19f5274da9
https://pubmed.ncbi.nlm.nih.gov/32481823
https://pubmed.ncbi.nlm.nih.gov/32481823
Autor:
Lynne J. Waddington, Nigel Kirby, Minoo J. Moghaddam, Abhishek Gupta, Liliana de Campo, Timothy Stait-Gardner, William S. Price
Publikováno v:
Journal of materials chemistry. B. 2(9)
Self-assembly of lipid-based amphiphiles into various supramolecular nanostructured particles has been used in creating novel nanomaterials with diverse applications in drug delivery and diagnostic imaging. Here we report on Gd(III) chelated DTPA amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea1dd242810485d8ddf7108f13911f9
https://pubmed.ncbi.nlm.nih.gov/32261359
https://pubmed.ncbi.nlm.nih.gov/32261359
Autor:
Sohel M. Julovi, Jerikho C. Bulanadi, Penelope A Bean, Ross C. Smith, Minoo J. Moghaddam, Xiaojuan Gong, Aiqun Xue, Liliana de Campo
Publikováno v:
ChemPlusChem. 85(6)
Gemcitabine (Gem) is a key drug for pancreatic cancer, yet limited by high systemic toxicity, low bioavailability and poor pharmacokinetic profiles. To overcome these limitations, Gem prodrug amphiphiles were synthesised with oleyl, linoleyl and phyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f95c69c9e61cefcfd9bea276bf86ed5
https://pubmed.ncbi.nlm.nih.gov/32543086
https://pubmed.ncbi.nlm.nih.gov/32543086
Autor:
Vindhya Kuruppu, Marina Ali, Nicholas Manolios, Nicola Barrie, Minoo J. Moghaddam, Emmanuel Manolios
Publikováno v:
International Journal of Rheumatic Diseases. 20:789-797
Preclinical and clinical studies using cannabis-based therapy have been shown to provide both analgesia and anti-inflammatory effects, with an overall alleviation of clinical symptoms in animal models of arthritis, highlighting its promising therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caeae09776accf86cf77aacf046f6eb3
https://doi.org/10.1111/1756-185x.13146
https://doi.org/10.1111/1756-185x.13146
Autor:
Dennis W. Hwang, Lynne J. Waddington, Abhishek Gupta, Liliana de Campo, William S. Price, Robert Knott, Nigel Kirby, Minoo J. Moghaddam
Publikováno v:
New Journal of Chemistry. 41:2735-2744
This paper reports on the synthesis, physicochemical characterisation and relaxation properties of a novel paramagnetic amphiphile, Gd–DTPA–Tris–trioleate (Gd–DTPA–Tris–TO), designed with the aim of obtaining paramagnetic nanoassemblies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a166150a18a5bc77f66729f43be9a54
https://doi.org/10.1039/c6nj03934k
https://doi.org/10.1039/c6nj03934k
Autor:
Timothy Stait-Gardner, Abhishek Gupta, Nigel Kirby, Minoo J. Moghaddam, Beenish Rehmanjan, Liliana de Campo, William S. Price, Scott A. Willis, Lynne J. Waddington
Publikováno v:
Langmuir. 31:1556-1563
Supramolecular self-assembling amphiphiles have been widely used in drug delivery and diagnostic imaging. In this report, we present the self-assembly of Gd (III) chelated DTPA-monophytanyl (Gd-DTPA-MP) amphiphiles incorporated within phytantriol (PT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97e54bc6ea8f18ea07d18a2e3b9a734
https://doi.org/10.1021/la5044969
https://doi.org/10.1021/la5044969
Autor:
Raghwa Sharma, Minoo J. Moghaddam, Eskandar Kamali-Sarvestani, Anne S. Vanniasinghe, Vijay Kumar, Veronika Bender, Nicholas Manolios, Stephen D. Schibeci, Marina Ali, C. Lakhiani
Publikováno v:
Clinical Immunology. 151:43-54
In this study we examined a synovium-specific targeted liposomal drug delivery system for its ability to localize and release its drug cargo to inflamed joints. Targeted liposomes were tested in vitro for binding to synovial fibroblast like (FLS) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c20692daa9aee01877e37f61a89d3e7
https://doi.org/10.1016/j.clim.2014.01.005
https://doi.org/10.1016/j.clim.2014.01.005
Autor:
Minoo J. Moghaddam, Xiaojuan Gong, Lynne J. Waddington, Charlotte E. Conn, Calum J. Drummond, Sharon M. Sagnella, Stephen J. Danon
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 85:349-359
An amphiphile prodrug, 5'-deoxy-5-fluoro-N(4)-(palmityloxycarbonyl) cytidine or 5'-deoxy-5-fluoro-N(4)-(hexadecanaloxycarbonyl) cytidine (5-FCPal), consisting of the same head group as the commercially available chemotherapeutic agent Capecitabine, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccd16f30ee35f2f4affe1207d084db0
https://doi.org/10.1016/j.colsurfb.2011.03.007
https://doi.org/10.1016/j.colsurfb.2011.03.007
Autor:
Lynne J. Waddington, Charlotte E. Conn, Xavier Mulet, Nigel Kirby, Minoo J. Moghaddam, Sharon M. Sagnella, Calum J. Drummond, Joseph N. Varghese, Connie Darmanin
Publikováno v:
Soft Matter. 7:567-578
Intrinsic difficulties in characterizing the structure of combined membrane protein–lyotropic liquid crystalline lipidic cubic systems have hampered the development of techniques such as membrane protein (MP) crystallization, which remain largely e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a1d79f31fe1ed594cc8feb8d91dd6b7
https://doi.org/10.1039/c0sm00790k
https://doi.org/10.1039/c0sm00790k