Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Minolfa C Prieto"'
Autor:
Paulina E. Larenas, Pilar Cárdenas, Monserrat Aguirre-Delgadillo, Carlos Moris, Dulce E. Casarini, Zoe Vallotton, Minolfa C. Prieto, Alexis A. Gonzalez
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-14 (2024)
Abstract Background During diabetes, prorenin is highly produced by the renal collecting ducts. The binding of prorenin to (pro)renin receptor (PRR) on the apical plasma membrane triggers intracellular profibrotic genes, including TGF-β and CTGF. Ho
Externí odkaz:
https://doaj.org/article/595c1cca1ead49cdb75b88937b92e12e
Publikováno v:
Exploration of Medicine, Vol 3, Iss 2, Pp 205-218 (2022)
Aim: Chronic high salt (HS) intake causes minimal changes in blood pressure (BP) but it induces augmented hypertensive response to angiotensin II (AngII) administration in rodents. The mechanism of this augmentation is not clearly understood. As tum
Externí odkaz:
https://doaj.org/article/fef0c76e34f44471b2bb4b8d37b810ad
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
The (Pro)renin receptor ([P]RR), also known as ATP6AP2, is a single-transmembrane protein that is implicated in a multitude of biological processes. However, the exact role of ATP6AP2 during blood vessel development remains largely undefined. Here, w
Externí odkaz:
https://doaj.org/article/cd762a9c55244eddafa9d8bdc073b59e
Autor:
Venkateswara R. Gogulamudi, Danielle Y. Arita, Camille R. T. Bourgeois, Justine Jorgensen, Jing He, William C. Wimley, Ryosuke Satou, Alexis A. Gonzalez, Minolfa C. Prieto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Growing evidence indicates that prorenin receptor (PRR) is upregulated in collecting duct (CD) of diabetic kidney. Prorenin is secreted by the principal CD cells, and is the natural ligand of the PRR. PRR activation stimulates fibrotic facto
Externí odkaz:
https://doaj.org/article/a8a795260c5844b2a75c6453cf8deb72
Autor:
Bruna Visniauskas, Danielle Y. Arita, Carla B. Rosales, Mohammed A. Feroz, Christina Luffman, Michael J. Accavitti, Gabrielle Dawkins, Jennifer Hong, Andrew C. Curnow, Tina K. Thethi, John J. Lefante, Edgar A. Jaimes, Franck Mauvais-Jarvis, Vivian A. Fonseca, Minolfa C. Prieto
Publikováno v:
Biology of Sex Differences, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Background The soluble prorenin receptor (sPRR), a member of the renin-angiotensin system (RAS), is elevated in plasma of patients with preeclampsia, hypertension, chronic kidney disease (CKD), and type 2 diabetes. Our goal was to examine th
Externí odkaz:
https://doaj.org/article/15b60cad9206474fba6afd8158c096b0
Autor:
Guiomar Nascimento Gomes, Minolfa C. Prieto, Karina Thieme, Heloisa Della Coletta Francescato
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/53ad424974f344eda4d1dc33ea8e7216
Publikováno v:
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Abstract In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor‐alpha (TNF‐α) levels increase. However, TNF‐α has been shown to suppress AGT form
Externí odkaz:
https://doaj.org/article/06ed98b1a3104f7eb664bb34ebd5a9be
Autor:
Bruna Visniauskas, Virginia Reverte, Caleb M. Abshire, Benard O. Ogola, Carla B. Rosales, Michelle Galeas-Pena, Venkata N. Sure, Siva S. V. P. Sakamuri, Nicholas R. Harris, Isabella Kilanowski-Doroh, Alexandra B. Mcnally, Alec C. Horton, Margaret Zimmerman, Prasad V. G. Katakam, Sarah H. Lindsey, Minolfa C. Prieto
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H762-H775
High-fat diet (HFD) for 28 wk leads to type 2 diabetes mellitus (T2DM) phenotype, concomitant with increased plasma soluble prorenin receptor (sPRR), nondipping blood pressure, and vascular stiffness in male mice. HFD-fed female mice exhibiting a pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98c5e22194928c5c11137f37b1550849
https://doi.org/10.1152/ajpheart.00638.2022
https://doi.org/10.1152/ajpheart.00638.2022
Autor:
Aarón Guerrero, Bruna Visniauskas, Pilar Cárdenas, Stefanny M. Figueroa, Jorge Vivanco, Nicolas Salinas-Parra, Patricio Araos, Quynh My Nguyen, Modar Kassan, Cristián A. Amador, Minolfa C. Prieto, Alexis A. Gonzalez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin to promote
Externí odkaz:
https://doaj.org/article/8b6d87c9c741445a88e2feac0178c38e
Autor:
Andrew C. Curnow, Sabrina R. Gonsalez, Venkateswara R. Gogulamudi, Bruna Visniauskas, Eric E. Simon, Alexis A. Gonzalez, Dewan S. A. Majid, Lucienne S. Lara, Minolfa C. Prieto
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
In the kidney, the stimulation of renin production by the collecting duct (CD-renin) contributes to the development of hypertension. The CD is a major nephron segment for the synthesis of nitric oxide (NO), and low NO bioavailability in the renal med
Externí odkaz:
https://doaj.org/article/7c8cf8ea09844711ab9a0667fca1f812