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Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice.

Autor: McIntosh A; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland., Mela V; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland., Harty C; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland., Minogue AM; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland., Costello DA; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland., Kerskens C; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland., Lynch MA; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.

Publikováno v: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2019 Sep; Vol. 29 (5), pp. 606-621. Date of Electronic Publication: 2019 Feb 17.

Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes.

Autor: Hawkins SJ; Regenerative Medicine Laboratory, School of Clinical Sciences, University of Bristol, Bristol, UK.; Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK., Crompton LA; Regenerative Medicine Laboratory, School of Clinical Sciences, University of Bristol, Bristol, UK.; Cell Biology Laboratories, School of Biochemistry, University of Bristol, Bristol, UK., Sood A; Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK., Saunders M; Cell Biology Laboratories, School of Biochemistry, University of Bristol, Bristol, UK.; Department of Medical Physics & Bioengineering, St Michael's Hospital, University Hospitals Bristol NHS Foundation Trust, Bristol, UK., Boyle NT; Trinity College Institute of Neuroscience, Department of Physiology, Trinity College Dublin, Dublin, Ireland., Buckley A; Trinity College Institute of Neuroscience, Department of Physiology, Trinity College Dublin, Dublin, Ireland., Minogue AM; Trinity College Institute of Neuroscience, Department of Physiology, Trinity College Dublin, Dublin, Ireland., McComish SF; Trinity College Institute of Neuroscience, Department of Physiology, Trinity College Dublin, Dublin, Ireland., Jiménez-Moreno N; Cell Biology Laboratories, School of Biochemistry, University of Bristol, Bristol, UK., Cordero-Llana O; Regenerative Medicine Laboratory, School of Clinical Sciences, University of Bristol, Bristol, UK., Stathakos P; Regenerative Medicine Laboratory, School of Clinical Sciences, University of Bristol, Bristol, UK.; Cell Biology Laboratories, School of Biochemistry, University of Bristol, Bristol, UK., Gilmore CE; Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK., Kelly S; Neuroscience Institute @JFK Medical Center, Edison, NJ, USA., Lane JD; Cell Biology Laboratories, School of Biochemistry, University of Bristol, Bristol, UK., Case CP; Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK., Caldwell MA; Trinity College Institute of Neuroscience, Department of Physiology, Trinity College Dublin, Dublin, Ireland. maeve.caldwell@tcd.ie.

Publikováno v: Nature nanotechnology [Nat Nanotechnol] 2018 May; Vol. 13 (5), pp. 427-433. Date of Electronic Publication: 2018 Apr 02.

Analysis of the Impact of CD200 on Phagocytosis.

Autor: Lyons A; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Minogue AM; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Jones RS; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Fitzpatrick O; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Noonan J; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Campbell VA; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Lynch MA; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland. lynchma@tcd.ie.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2017 Sep; Vol. 54 (7), pp. 5730-5739. Date of Electronic Publication: 2016 Nov 09.

Involvement of IGF-1 and Akt in M1/M2 activation state in bone marrow-derived macrophages.

Autor: Barrett JP; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Minogue AM; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland. Electronic address: aminogu@tcd.ie., Falvey A; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland., Lynch MA; Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland.

Publikováno v: Experimental cell research [Exp Cell Res] 2015 Jul 15; Vol. 335 (2), pp. 258-68. Date of Electronic Publication: 2015 May 28.