Personalised human albumin in patients with cirrhosis and ascites: design and rationale for the ALB-TRIAL - a randomised clinical biomarker validation trial

Autor: Torben Hansen, Pere Ginès, Wim Laleman, Peer Bork, Vishal C Patel, Debbie Shawcross, Robert Schierwagen, Camila Alvarez-Silva, Florence Servant, Jonel Trebicka, Benjamin Lelouvier, Manimozhiyan Arumugam, Ed J Kuijper, Frank Erhard Uschner, Michael Praktiknjo, Mária Papp, Saeed Shoaie, Michael Kühn, Maja Thiele, Paolo Angeli, Joan Claria, Vicente Arroyo, Manolo Laiola, Benoit Quinquis, Sabine Klein, Minneke J Coenraad, François Fenaille, Debbie Lindsay Shawcross, Wenyi Gu, Adria Juanola, Elisa Pose, Aleksander Krag, Ivica Letunic, Alain Pruvost, Hervé M Blottière, Nathalie Galleron, Cristina López-Vicario, Peter V Treit, Matthias Mann, Jelle Matthijnssens, Mark J W Mcphail, Philipp E Geyer, Hans Olav Melberg, Stefanie Kandels, Cristina Sánchez-Garrido, Florence A Castelli, Christophe Junot, Lars Asphaug, Mads Israelsen, Helene Bæk Juel, Nikolaj Torp, Minneke Coenraad, Marko Korenjak, Ferran Aguilar-Parera, Patricia Sierra-Casas, Anna Bosch-Comas, David Tornai, Boglarka Balogh, Katrine Holtz Thorhauge, Casper Sahl Poulsen, Thea Van Rossum, Suguru Nishijima, Marisa I Keller, Diënty H M Hazenbrink, Sylvain Dechaumet, Sebastian D Burz, Emeline Chu-Van, Etienne Thévenot, Florian A Rosenberger, Sebastian Van Blerk, Amirouche Ouzerdine, Alain Roulet, Jean-Louis-Marie Insonere, Céline Serres, Mathieu Almeida, Florence Thirion, Camille Champion, Chaima Ezzine, Célia Chamignon, Nicolas Lapaque, Mamadou Gabou Thiam, Lore Van Espen, Quinten R Ducarmon, Annelotte GC Broekhoven, Susan Fischer, Romy Zwittink, Itziar De Lecuona, Giulio Rosati, Celia Fuentes-Chust, Arben Merkoçi, Massimo Urban, José Alfonso Marrugo-Ramirez, Ameli Schwalber, Lindsey Ann Edwards, Victoria Tatiana Kronsten, David Moyes, Azadeh Harzandi, Jordi Gratacós-Ginès, Martina Pérez-Guasch, Miriam Pellón, Bryan Contreras, Max Brol, Manfred Fobker, Renata Antonina Feuerborn

Publikováno v: BMJ Open, Vol 14, Iss 2 (2024)

Introduction Human albumin is used in the treatment of complications of cirrhosis. However, the use of long-term human albumin administration is costly and resource demanding for both patients and healthcare systems. A precision medicine approach wit

Externí odkaz: https://doaj.org/article/289f12a27d2047adb5cb758cb2809703

Copeptin in acute decompensation of liver cirrhosis: relationship with acute-on-chronic liver failure and short-term survival

Autor: Annarein J. C. Kerbert, Hein W. Verspaget, Àlex Amorós Navarro, Rajiv Jalan, Elsa Solà, Daniel Benten, François Durand, Pere Ginès, Johan J. van der Reijden, Bart van Hoek, Minneke J. Coenraad, for the CANONIC Study Investigators of the EASL-CLIF Consortium

Publikováno v: Critical Care, Vol 21, Iss 1, Pp 1-11 (2017)

Abstract Background Acute-on-chronic liver failure (ACLF) is characterized by the presence of acute decompensation (AD) of cirrhosis, organ failure, and high short-term mortality rates. Hemodynamic dysfunction and activation of endogenous vasoconstri

Externí odkaz: https://doaj.org/article/65fbae07ec7b4cfeb818b44d824cfa09

Addressing Profiles of Systemic Inflammation Across the Different Clinical Phenotypes of Acutely Decompensated Cirrhosis

Autor: Jonel Trebicka, Alex Amoros, Carla Pitarch, Esther Titos, José Alcaraz-Quiles, Robert Schierwagen, Carmen Deulofeu, Javier Fernandez-Gomez, Salvatore Piano, Paolo Caraceni, Karl Oettl, Elsa Sola, Wim Laleman, Jane McNaughtan, Rajeshwar P. Mookerjee, Minneke J. Coenraad, Tania Welzel, Christian Steib, Rita Garcia, Thierry Gustot, Miguel A. Rodriguez Gandia, Rafael Bañares, Agustin Albillos, Stefan Zeuzem, Victor Vargas, Faouzi Saliba, Frederic Nevens, Carlo Alessandria, Andrea de Gottardi, Heinz Zoller, Pere Ginès, Tilman Sauerbruch, Alexander Gerbes, Rudolf E. Stauber, Mauro Bernardi, Paolo Angeli, Marco Pavesi, Richard Moreau, Joan Clària, Rajiv Jalan, Vicente Arroyo

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Background: Patients with acutely decompensated cirrhosis (AD) may or may not develop acute-on-chronic liver failure (ACLF). ACLF is characterized by high-grade systemic inflammation, organ failures (OF) and high short-term mortality. Although patien

Externí odkaz: https://doaj.org/article/c9ee1acb66ec47d2b1c7d33f99d3719c

Patients with a History of Bariatric Surgery Are 8 Years Younger at Presentation with Severe Alcoholic Hepatitis

Autor: Lukas Van Melkebeke, Annelotte G. C. Broekhoven, Tessa Ostyn, Hannelie Korf, Minneke J. Coenraad, Roman Vangoitsenhoven, Bart Van der Schueren, Matthias Lannoo, Hannah Van Malenstein, Tania Roskams, Schalk van der Merwe, Frederik Nevens, Jef Verbeek

Publikováno v: Obesity Surgery, 33(1), 284-292. SPRINGER

Purpose: Patients with prior bariatric surgery (BS) are at risk to develop alcohol use disorder (AUD) and alcohol-related liver disease (ALD). Severe alcoholic hepatitis (sAH) is one of the most severe manifestations of ALD with a 28-day mortality of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195c1b5828f3fcac99620242ddbf83b8
https://pubmed.ncbi.nlm.nih.gov/36460941

Study Protocol PROMETHEUS: Prospective Multicenter Study to Evaluate the Correlation Between Safety Margin and Local Recurrence After Thermal Ablation Using Image Co-registration in Patients with Hepatocellular Carcinoma

Autor: Timo T. M. Oosterveer, Gonnie C. M. van Erp, Pim Hendriks, Alexander Broersen, Christiaan G. Overduin, Carla S. P. van Rijswijk, Arian R. van Erkel, Rutger W. van der Meer, Maarten E. Tushuizen, Adriaan Moelker, Martijn R. Meijerink, Otto M. van Delden, Koert P. de Jong, Christiaan van der Leij, Maarten L. J. Smits, Thijs A. J. Urlings, Jeffrey P. B. M. Braak, Elma Meershoek-Klein Kranenbarg, Bianca van Duijn-de Vreugd, Evelijn Zeijdner, Jelle J. Goeman, Jurgen J. Fütterer, Minneke J. Coenraad, Jouke Dijkstra, Mark C. Burgmans

Publikováno v: Cardiovascular and Interventional Radiology, 45, 5, pp. 606-612
CardioVascular and Interventional Radiology, 45(5), 606-612. Springer Verlag
Cardiovascular and Interventional Radiology, 45, 606-612
CardioVascular and Interventional Radiology, 45, 606-612. SPRINGER
Cardiovascular and interventional radiology, 45(5), 606-612. Springer Verlag
Cardiovascular and Interventional Radiology, 45(5), 606-612. Springer, Cham
Cardiovascular and interventional radiology, 45(5), 606-612. SPRINGER
Oosterveer, T T M, van Erp, G C M, Hendriks, P, Broersen, A, Overduin, C G, van Rijswijk, C S P, van Erkel, A R, van der Meer, R W, Tushuizen, M E, Moelker, A, Meijerink, M R, van Delden, O M, de Jong, K P, van der Leij, C, Smits, M L J, Urlings, T A J, Braak, J P B M, Meershoek-Klein Kranenbarg, E, van Duijn-de Vreugd, B, Zeijdner, E, Goeman, J J, Fütterer, J J, Coenraad, M J, Dijkstra, J & Burgmans, M C 2022, ' Study Protocol PROMETHEUS : Prospective Multicenter Study to Evaluate the Correlation Between Safety Margin and Local Recurrence After Thermal Ablation Using Image Co-registration in Patients with Hepatocellular Carcinoma ', CardioVascular and Interventional Radiology, vol. 45, no. 5, pp. 606-612 . https://doi.org/10.1007/s00270-022-03075-5
CardioVascular and Interventional Radiology, 45(5), 606-612. Springer-Verlag

Purpose The primary objective is to determine the minimal ablation margin required to achieve a local recurrence rate of Materials and Methods This study is a prospective, multicenter, non-experimental, non-comparative, open-label study. Patients > 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c57e9c59999847027a5cb3de9957088