Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Minna Riekkinen"'
Autor:
Minna Riekkinen, Jukka Sallinen, Mika Scheinin, Markus Björklund, Paavo Riekkinen, Jouni Sirviö
Publikováno v:
Neuroscience. 95:481-487
We investigated the role of overexpression of alpha2C-adrenoceptors in water maze navigation in mice transgenically manipulated to have a threefold overexpression of the alpha2C-adrenoreceptors. Alpha2C-adrenoreceptors overexpressing mice swam more i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a721bbabc93bc8d80fa0a5e96e6d607
https://doi.org/10.1016/s0306-4522(99)00428-5
https://doi.org/10.1016/s0306-4522(99)00428-5
Autor:
Paavo Riekkinen, Minna Riekkinen
Publikováno v:
Journal of Clinical Psychopharmacology. 19:444-449
The loss of dopaminergic cells during Parkinson's disease (PD) produces "frontal"-like impairment in spatial working memory (SWM) and planning functions. This study investigated whether an alpha2-adrenergic agonist, clonidine (0.5 or 2 microg/kg, ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab026e981e584c586e02f3f7f6aea75e
https://doi.org/10.1097/00004714-199910000-00008
https://doi.org/10.1097/00004714-199910000-00008
Publikováno v:
Neuroscience. 92:975-982
We investigated the effect of the alpha2-agonist, clonidine (orally: 0.5 and 2 microg/kg), administration on parameters assessing attention and short-term recognition memory in Alzheimer's disease patients. Clonidine 2 microg/kg, but not 0.5 microg/k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60efae6141aa11debf814b698ea18fe6
https://doi.org/10.1016/s0306-4522(99)00070-6
https://doi.org/10.1016/s0306-4522(99)00070-6
Autor:
Minna Riekkinen, Jouni Sirviö, Pekka Jäkälä, Kosti Kejonen, Esa Koivisto, Matti Vanhanen, Paavo J. Riekkinen
Publikováno v:
Neuropsychopharmacology. 20:119-130
The present study compares the effects of two alpha 2-agonists, clonidine (0.5, 2, and 5 micrograms/kg, p.o.) and guanfacine (7 and 29 micrograms/kg, p.o.) in young healthy volunteers on their performance in visual paired associates learning (PAL) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827f276fedbaa1726e26b0861653e310
https://doi.org/10.1016/s0893-133x(98)00055-4
https://doi.org/10.1016/s0893-133x(98)00055-4
Publikováno v:
NeuroReport. 9:3647-3651
The present study examined the efficacy of single and combined treatments with an anticholinesterase, tetrahydroaminoacridine, nicotine and a glycine-B site partial agonist, D-cycloserine, in alleviating the water maze reversal learning defect induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca7d30214082526e7e66e120946e523
https://doi.org/10.1097/00001756-199811160-00016
https://doi.org/10.1097/00001756-199811160-00016
Publikováno v:
European Journal of Neuroscience. 10:1429-1435
We investigated the role dopamine and noradrenaline in the modulation of attention in Parkinson's disease (PD) patients. We observed that PD patients with mild and moderate motor disability did not differ in their attentional accuracy in easy tests,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6765ee86804978628131aa8be42c9722
https://doi.org/10.1046/j.1460-9568.1998.00145.x
https://doi.org/10.1046/j.1460-9568.1998.00145.x
Publikováno v:
European Journal of Pharmacology. 323:11-19
We investigated the effects of acute oral pretraining treatment with an indirect acetylcholinesterase inhibitor, metrifonate, on water maze spatial navigation in medial septum-lesioned rats. We observed that metrifonate (30 mg/kg, orally) (1) does no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2293ca193bc27a2c5e9a52723e60ce23
https://doi.org/10.1016/s0014-2999(97)00016-2
https://doi.org/10.1016/s0014-2999(97)00016-2
Autor:
Paavo Riekkinen, Minna Riekkinen
Publikováno v:
NeuroReport. 8:699-703
WE investigated the effect of nicotine, a nicotinic agonist, and D-cycloserine (DCS, a partial glycine-B agonist of the N-methyl-D-aspartate (NMDA) receptor complex) on aging-induced defects of water maze (WM) spatial navigation in rats. Nicotine (0.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358b5ed9b54f927489ef195e9eb8469d
https://doi.org/10.1097/00001756-199702100-00024
https://doi.org/10.1097/00001756-199702100-00024
Autor:
Tarja Puumala, Paavo Riekkinen, Pekka Jäkälä, Jouni Sirviö, Minna Riekkinen, Erkki Björk, Antti Haapalinna, Markus Björklund, Sirja Ruotsalainen
Publikováno v:
Brain Research Bulletin. 43:163-171
A five-choice serial reaction time (5-CSRT) task was used to assess attention in rats. In this behavioral paradigm, the rats are required to spatially discriminate a short visual stimulus that will occur randomly in one of five locations while mainta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9f2c5f0ae51527f3e9551cdeddc97a
https://doi.org/10.1016/s0361-9230(96)00433-9
https://doi.org/10.1016/s0361-9230(96)00433-9
Autor:
Markus Björklund, Minna Riekkinen, Paavo Riekkinen, Esa Koivisto, Pekka Jäkälä, Bernard Schmidt
Publikováno v:
European Journal of Pharmacology. 318:239-250
The present study investigated if short-term treatment with an L-type Ca2+-channel inhibitor, nimodipine, can stimulate cognitive functioning and cortical electroencephalograph (EEG) arousal, and potentiate the effect of a cholinesterase inhibitor, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16749a6fd23cdab64ebbdf7906ae5622
https://doi.org/10.1016/s0014-2999(96)00787-x
https://doi.org/10.1016/s0014-2999(96)00787-x