Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Minna Ampuja"'
Autor:
Martin Broberg, Minna Ampuja, Samuel Jones, Tiina Ojala, Otto Rahkonen, Riikka Kivelä, James Priest, FinnGen, Aarno Palotie, Hanna M. Ollila, Emmi Helle
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Congenital heart defects (CHD) are structural defects of the heart affecting approximately 1% of newborns. They exhibit low penetrance and non-Mendelian patterns of inheritance as varied and complex traits. While genetic factors a
Externí odkaz:
https://doaj.org/article/c8b8a945cab44e5eba3e205c0ac94c08
Autor:
Emmi Helle, Minna Ampuja, Alexandra Dainis, Laura Antola, Elina Temmes, Erik Tolvanen, Eero Mervaala, Riikka Kivelä
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cell-cell interactions are crucial for organ development and function. In the heart, endothelial cells engage in bidirectional communication with cardiomyocytes regulating cardiac development and growth. We aimed to elucidate the organotypic developm
Externí odkaz:
https://doaj.org/article/3791680514c546ae8bc919751bd05982
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The vascular system is essential for the development and function of all organs and tissues in our body. The molecular signature and phenotype of endothelial cells (EC) are greatly affected by blood flow-induced shear stress, which is a vital compone
Externí odkaz:
https://doaj.org/article/90b8434cca9b43128ab997ad4395bbe9
Autor:
Minna Ampuja, Anne Kallioniemi
Publikováno v:
Genes, chromosomescancer. 57(1)
Bone morphogenetic proteins (BMPs) are a family of growth factors, some of which are known by the name growth and differentiation factor (GDF). BMPs were discovered in the 1960s in an attempt to find factors capable of inducing bone formation. By the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c1ca12de9f22fce7a88fd0a2555c36
https://pubmed.ncbi.nlm.nih.gov/28857319
https://pubmed.ncbi.nlm.nih.gov/28857319
Autor:
Riikka Havunen, Harold L. Moses, Anne Kallioniemi, Agnieszka E. Gorska, Minna Ampuja, Philip Owens, Emma-Leena Alarmo
Publikováno v:
Cancer letters. 375(2)
Bone morphogenetic protein 4 (BMP4) is a key regulator of cell proliferation and differentiation. In breast cancer cells, BMP4 has been shown to reduce proliferation in vitro and interestingly, in some cases, also to induce migration and invasion. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7d9bac5eee001c7edbb41dc248d5eb
https://pubmed.ncbi.nlm.nih.gov/26970275
https://pubmed.ncbi.nlm.nih.gov/26970275
Publikováno v:
Experimental Cell Research. 317:2136-2146
Bone morphogenetic proteins (BMPs) are multifunctional signaling molecules that have gained increasing interest in cancer research. To obtain a systematic view on BMP signaling in pancreatic cancer we first determined the mRNA expression levels of se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dc8f48deab113831a671054e93ad8c
https://doi.org/10.1016/j.yexcr.2011.06.001
https://doi.org/10.1016/j.yexcr.2011.06.001
Autor:
Emma Leena Alarmo, Philip Owens, Agnes E. Gorska, Anne Kallioniemi, Riikka Havunen, Harold L. Moses, Minna Ampuja
Publikováno v:
Cancer Research. 76:629-629
Background. Breast cancer is the most common cancer in women worldwide. Bone morphogenetic proteins (BMPs), members of the transforming growth factor β superfamily, are known to regulate cell proliferation, differentiation and motility, and have als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d68f04080711e4772d87cf9ce7c21f
https://doi.org/10.1158/1538-7445.am2016-629
https://doi.org/10.1158/1538-7445.am2016-629
Autor:
Felix Treumer, Monica Nieminen, Kati Juuti-Uusitalo, Alexa Klettner, Minna Ampuja, Heli Skottman, Anne Kallioniemi
Publikováno v:
Investigative Opthalmology & Visual Science. 56:6265
PURPOSE In several retinal complications, such as age-dependent macular degeneration (AMD), oxidative stress is increased and cytokine level is elevated. These are shown to alter the activation and expression of matrix metalloproteinase (MMP) both in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea0d35a731d1d1ae500b12aad130d8b
https://doi.org/10.1167/iovs.15-17333
https://doi.org/10.1167/iovs.15-17333
Autor:
Alejandra Rodriguez-Martinez, Riikka Jokimäki, Anne Kallioniemi, Kati Juuti-Uusitalo, Minna Ampuja, Emma-Leena Alarmo
Publikováno v:
BMC Cancer
Background Bone morphogenetic protein 4 (BMP4) belongs to the transforming growth factor β (TGF-β) family of proteins. BMPs regulate cell proliferation, differentiation and motility, and have also been reported to be involved in cancer pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3923bc1bce2ad0d2f71d0f2f26863d7d
http://europepmc.org/articles/PMC3848934
http://europepmc.org/articles/PMC3848934
Publikováno v:
Cancer Research. 73:1397-1397
Bone morphogenetic protein 4 (BMP4) is an extracellular signaling molecule that belongs to the bone morphogenetic protein (BMP) family, which in turn is part of the transforming growth factor β (TGF-β) -superfamily. BMPs regulate cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaf922a25605b0ea0bf6090c013947d3
https://doi.org/10.1158/1538-7445.am2013-1397
https://doi.org/10.1158/1538-7445.am2013-1397