Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Minna, Woo"'
Autor:
Kenneth K. Y. Ting, Pei Yu, Riley Dow, Hisham Ibrahim, Saraf Karim, Chanele K. Polenz, Daniel A. Winer, Minna Woo, Jenny Jongstra-Bilen, Myron I. Cybulsky
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Lipid accumulation in macrophages (Mφs) is a hallmark of atherosclerosis. Yet, how lipid loading modulates Mφ inflammatory responses remains unclear. We endeavored to gain mechanistic insights into how pre-loading with free cholesterol mod
Externí odkaz:
https://doaj.org/article/911cea6d5d134c2c8c4a5e9662c77c10
Autor:
Cigdem Sahin, Jenna-Rose Melanson, Florian Le Billan, Lilia Magomedova, Thais A.M. Ferreira, Andressa S. Oliveira, Evan Pollock-Tahari, Michael F. Saikali, Sarah B. Cash, Minna Woo, Luiz A.S. Romeiro, Carolyn L. Cummins
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101958- (2024)
Objective: The prevalence of metabolic diseases is increasing globally at an alarming rate; thus, it is essential that effective, accessible, low-cost therapeutics are developed. Peroxisome proliferator-activated receptors (PPARs) are transcription f
Externí odkaz:
https://doaj.org/article/cfebdf9a904b44948be866fb0310321e
Publikováno v:
In Canadian Journal of Diabetes December 2011 35(5):488-489
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Neurodegenerative disorders are accompanied by neuronal degeneration and glial dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors including genetic, environmental, metabolic, and oxidant overload co
Externí odkaz:
https://doaj.org/article/80676e65e14a46b6acd947c375a661f9
Publikováno v:
Journal of Biological Engineering, Vol 16, Iss 1, Pp 1-9 (2022)
Abstract Chronic myeloid leukemia is generally required bone marrow biopsy for diagnosis. Although examining peripheral blood is less invasive, it has not been fully validated as a routine diagnostic test due to suboptimal sensitivity. To overcome th
Externí odkaz:
https://doaj.org/article/a89a46a961504ee9ad3c88ff8343e4d0
Publikováno v:
Biological Procedures Online, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background Micro RNA of Marsupenaeus japonicas has been known to promote apoptosis of tumor cells. However, the detailed mechanisms are not well understood. Results Using tomographic microscope, which can detect the internal structure of cel
Externí odkaz:
https://doaj.org/article/5c7bf728830f4cc1a310929b02362c53
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Tumor cells can respond to therapeutic agents by morphologic alternations including formation of tunneling nanotubes. Using tomographic microscope, which can detect the internal structure of cells, we found that mitochondria within breast tu
Externí odkaz:
https://doaj.org/article/29c66e79c729412692e7acde954829d3
Autor:
Idit Dotan, Jiaqi Yang, Jiro Ikeda, Ziv Roth, Evan Pollock-Tahiri, Harsh Desai, Tharini Sivasubramaniyam, Sonia Rehal, Josh Rapps, Yu Zhe Li, Helen Le, Gedaliah Farber, Edouard Alchami, Changting Xiao, Saraf Karim, Marcela Gronda, Michael F. Saikali, Amit Tirosh, Kay-Uwe Wagner, Jacques Genest, Aaron D. Schimmer, Vikas Gupta, Mark D. Minden, Carolyn L. Cummins, Gary F. Lewis, Clinton Robbins, Jenny Jongstra-Bilen, Myron Cybulsky, Minna Woo
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Loss of myeloid JAK2 promotes atherosclerosis in an ApoE knockout mouse model. This is associated with decreased cholesterol efflux from bone-marrow-derived macrophages.
Externí odkaz:
https://doaj.org/article/8f5bbf65f53546318be8781e62cd0a46
Autor:
Tharini Sivasubramaniyam, Jiaqi Yang, Henry S. Cheng, Alexandra Zyla, Angela Li, Rickvinder Besla, Idit Dotan, Xavier S. Revelo, Sally Yu Shi, Helen Le, Stephanie A. Schroer, David W. Dodington, Yoo Jin Park, Min Jeong Kim, Daniella Febbraro, Isabelle Ruel, Jacques Genest, Raymond H. Kim, Tak W. Mak, Daniel A. Winer, Clinton S. Robbins, Minna Woo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Inflammation is a key contributor to atherosclerosis with macrophages playing a pivotal role through the induction of oxidative stress and cytokine/chemokine secretion. DJ1, an anti-oxidant protein, has shown to paradoxically protect against
Externí odkaz:
https://doaj.org/article/dd1b0c94e3934c83829b8e94c00d30fc
Autor:
Dmitry Rozenberg, Daniel Santa Mina, Sahar Nourouzpour, Encarna Camacho Perez, Brooke Lyn Stewart, Lisa Wickerson, Cynthia Tsien, Nazia Selzner, Josh Shore, Meghan Aversa, Minna Woo, Sandra Holdsworth, Karina Prevost, Jeff Park, Amirhossein Azhie, Ella Huszti, Elizabeth McLeod, Sarah Dales, Mamatha Bhat
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 3, p e35700 (2022)
BackgroundPosttransplant metabolic syndrome (PTMS) is a common contributor to morbidity and mortality among solid organ transplant recipients in the late posttransplant period (≥1 year). Patients diagnosed with PTMS are at a higher risk of cardiova
Externí odkaz:
https://doaj.org/article/1c5b0644d74e4e36b7165e7385f7babf