Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Minmin Qu"'
Autor:
Minmin Qu, Jia Chen, Bin Xu, Qinyun Shi, Shujing Zhao, Zhaoxia Wang, Zhi Li, Bo Ma, Hua Xu, Qinong Ye, Jianwei Xie
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Chemotherapy has already proven widely effective in treating cancer. Chemotherapeutic agents usually include DNA damaging agents and non-DNA damaging agents. Assessing genotoxic effect is significant during chemotherapy drug development, since the ab
Externí odkaz:
https://doaj.org/article/aedd148a29764bfe9ac470707d745799
Autor:
Hongling Zhao, Minmin Qu, Yuchen Li, Ke Wen, Hua Xu, Man Song, Dafei Xie, Xingkun Ao, Yihao Gong, Li Sui, Hua Guan, Pingkun Zhou, Jianwei Xie
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
Exposure to environmental ionizing radiation (IR) is ubiquitous, and large-dose exposure to IR is known to cause DNA damage and genotoxicity which is associated with an increased risk of cancer. Whether such detrimental effects are caused by exposure
Externí odkaz:
https://doaj.org/article/812d1cc770bf4680b9a51c0c76d987e3
Publikováno v:
Chemical Research in Toxicology. 33:2108-2119
Genotoxic chemicals act by causing DNA damage, which, if left unrepaired, can have deleterious consequences for cell survival. DNA damage response (DDR) gets activated to repair or mitigate the effects of DNA damage. Histone H2AX and H3 phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807c96f5315b94677ba88caa1d7b13bf
https://doi.org/10.1021/acs.chemrestox.0c00104
https://doi.org/10.1021/acs.chemrestox.0c00104
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 81
Aristolochic acids (AAs) are known to be the potent genotoxic carcinogens, of which aristolochic acid I (AAI) and aristolochic acid II (AAII) are the two representative compounds. As the carcinogenic risk of herbs containing AAs is a global health is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11481a41f4019c6933a4976107a36c93
https://pubmed.ncbi.nlm.nih.gov/35307501
https://pubmed.ncbi.nlm.nih.gov/35307501
Autor:
Zhi Li, Yajiao Zhang, Minmin Qu, Wuju Li, Hua Xu, Tao Liu, Lei Guo, Bin Xu, Jia Chen, Jianwei Xie
Publikováno v:
Archives of toxicology. 95(11)
Amongst all toxicological endpoints, carcinogenicity might pose the greatest concern. Genetic damage has been considered an important underlying mechanism for the carcinogenicity of chemical substances. The demand for in vitro genotoxic tests as alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5807f740fae1cfdce08f1dfbdac9b392
https://pubmed.ncbi.nlm.nih.gov/34510228
https://pubmed.ncbi.nlm.nih.gov/34510228
Publikováno v:
Talanta. 224
Reduced glutathione (GSH) and the oxidized glutathione (GSSG) are well-known biomolecules in the main constituents of intracellular redox homeostasis system. A rapid, accurate measurement of cellular GSH and GSSG is quite needed in investigating impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52e4678accb8570a7aa4e88f65ff388
https://pubmed.ncbi.nlm.nih.gov/33379068
https://pubmed.ncbi.nlm.nih.gov/33379068