Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Minli Xing"'
Autor:
Xiaoqing Wu, Remya Ramesh, Jinan Wang, Youguang Zheng, Ahlam M. Armaly, Lanjing Wei, Minli Xing, Sudeshna Roy, Lan Lan, Fei Philip Gao, Yinglong Miao, Liang Xu, Jeffrey Aubé
Publikováno v:
Journal of Medicinal Chemistry. 66:2032-2053
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19ec781c4b0b07e71bf2d93634421628
https://doi.org/10.1021/acs.jmedchem.2c01723
https://doi.org/10.1021/acs.jmedchem.2c01723
Autor:
Michael S. Wolfe, Minli Xing, Kathleen M. Meneely, Justin T. Douglas, Sujan Devkota, Sanjay Bhattarai
Publikováno v:
J Am Chem Soc
γ-Secretase is a membrane-embedded aspartyl protease complex central in biology and medicine. How this enzyme recognizes transmembrane substrates and catalyzes hydrolysis in the lipid bilayer is unclear. Inhibitors that mimic the entire substrate tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1e6a05d0f7d44041cdd4a617830765
https://doi.org/10.1021/jacs.9b13405
https://doi.org/10.1021/jacs.9b13405
Autor:
Kevin P. Battaile, Maithri M. Kashipathy, Minli Xing, Lan Lan, Liang Xu, Philip Gao, Robert P. Hanzlik, Scott Lovell, Justin T. Douglas
Publikováno v:
Proteins
Musashi‐2 (MSI2) belongs to Musashi family of RNA binding proteins (RBP). Like Musashi‐1 (MSI1), it is overexpressed in a variety of cancers and is a promising therapeutic target. Both MSI proteins contain two N‐terminal RNA recognition motifs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab6dc335c066e6daf0ab1abe6a20690
https://doi.org/10.1002/prot.25836
https://doi.org/10.1002/prot.25836
Autor:
Minli Xing, Kristi L. Neufeld, Audrey L. Lamb, Justin T. Douglas, Aaron J. Rudeen, W. Hayes McDonald
Publikováno v:
Biochemistry
The tumor suppressor Adenomatous polyposis coli (APC) is a large, multidomain protein with many identified cellular functions. The best characterized role of APC is to scaffold a protein complex that negatively regulates Wnt signaling via β-catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94adb8b72ae5df4769bf60c437bac768
https://pubmed.ncbi.nlm.nih.gov/32941008
https://pubmed.ncbi.nlm.nih.gov/32941008
Autor:
Anuradha Roy, Lan Lan, Liang Xu, Minli Xing, Xiaoqing Wu, Kristi L. Neufeld, John Karanicolas, Carl Appelman, Ke Li, Roberto N. De Guzman, Ragul Gowthaman, Jinan Wang, Amber D. Somoza, Clay C. C. Wang, Jiajun Liu, Amber R. Smith, Berl R. Oakley, Yinglong Miao
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2221, p 2221 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2221, p 2221 (2020)
RNA-binding protein Musashi-1 (MSI1) is a key regulator of several stem cell populations. MSI1 is involved in tumor proliferation and maintenance, and it regulates target mRNAs at the translational level. The known mRNA targets of MSI1 include Numb,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e7e0795e4148eaee3bef3e022c99c8
Autor:
Lan, Lan, Jiajun, Liu, Minli, Xing, Amber R, Smith, Jinan, Wang, Xiaoqing, Wu, Carl, Appelman, Ke, Li, Anuradha, Roy, Ragul, Gowthaman, John, Karanicolas, Amber D, Somoza, Clay C C, Wang, Yinglong, Miao, Roberto, De Guzman, Berl R, Oakley, Kristi L, Neufeld, Liang, Xu
Publikováno v:
Cancers
RNA-binding protein Musashi-1 (MSI1) is a key regulator of several stem cell populations. MSI1 is involved in tumor proliferation and maintenance, and it regulates target mRNAs at the translational level. The known mRNA targets of MSI1 include Numb,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0eb8ef974a06014a7fe6c6989c67a83a
https://pubmed.ncbi.nlm.nih.gov/32784494
https://pubmed.ncbi.nlm.nih.gov/32784494
Autor:
Lan Lan, Minli Xing, Maithri Kashipathy, Justin Douglas, Philip Gao, Kevin Battaile, Robert Hanzlik, Scott Lovell, Liang Xu
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a416bc9ef34b3257d352bc3733f9c5
https://doi.org/10.1002/prot.25718
https://doi.org/10.1002/prot.25718
Autor:
Charles Avery Sader, Nina C. Gonnella, Klaus Wagner, Minli Xing, Udo Fischer, Keith R. Fandrick, Paul-James Jones, Dongyue Xin
Publikováno v:
Organic & Biomolecular Chemistry. 15:928-936
The calculation of 15N NMR chemical shifts has been systematically investigated using density functional theory-gauge including/invariant atomic orbitals (DFT-GIAO) approximation at the B3LYP/cc-pVDZ level of theory. General linear regression terms f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2870149e7380d92f474fa876fe542069
https://doi.org/10.1039/c6ob02450e
https://doi.org/10.1039/c6ob02450e
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:177-181
Zoocin A is a Zn-metallopeptidase secreted by Streptococcus zooepidemicus strain 4881. Its catalytic domain is responsible for cleaving the D-alanyl-L-alanine peptide bond in streptococcal peptidoglycan. The solution NMR structure of the Cys74 to Ala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08104f14569718997ef5bbf7c5909b43
https://doi.org/10.1002/prot.25178
https://doi.org/10.1002/prot.25178
Autor:
Liang Xu, Lan Lan, Kevin P. Battaile, Philip Gao, Robert P. Hanzlik, Justin T. Douglas, Minli Xing, Scott Lovell, Maithri M. Kashipathy
Publikováno v:
Cancer Research. 80:4140-4140
RNA-binding proteins (RBPs) are key regulators of cellular functions, especially in post-transcriptional regulations. Dysregulation of RBPs is implicated in many diseases including cancer. One of the RBPs that is overexpressed in a variety of human c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fb5010a280e2bd04db32ddd0fb1fa5b
https://doi.org/10.1158/1538-7445.am2020-4140
https://doi.org/10.1158/1538-7445.am2020-4140