Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Minlei Zhang"'
Autor:
Alexander Fichtner, Carlos Cabrera Ruiz, Crisanto Guadiz, Boris Gorovits, Minlei Zhang, John Kamerud, Zhihua Jiang
Publikováno v:
Bioanalysis. 12:1279-1293
Aim: Drug interference poses great analytical challenges for cell-based neutralizing antidrug antibodies (NAb) assay. The work aimed to improve assay drug tolerance through biotin-drug extraction with acid dissociation method optimization and develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c11a4ed277f00f451a996557cb58e20
https://doi.org/10.4155/bio-2020-0091
https://doi.org/10.4155/bio-2020-0091
Autor:
Christopher J. Bowman, Mengmeng Wang, Michael J. Potchoiba, Gerhard F. Weinbauer, Denise O'Hara, Natasha R. Catlin, Andrea Z Mitchell, Minlei Zhang
Publikováno v:
Birth Defects Research. 112:105-117
Antibody-like biopharmaceuticals cross the placenta by utilizing existing transport pathways (e.g., FcRn receptor). There are limited data evaluating this transfer during organogenesis in any species. Understanding placental transfer of antibody-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7678b0143cd57b67f5cebd7e8c5da14
https://doi.org/10.1002/bdr2.1615
https://doi.org/10.1002/bdr2.1615
Autor:
David Cirelli, Laird Bloom, Orla Cunningham, Lindsay B. Avery, William J.J. Finlay, Denise O'Hara, Barry McDonnell, Minlei Zhang, Steve Penn, Brian J. Fennell, Amy Tam, Mania Kavosi, Laura Lin, Paul Sakorafas, Rhys M. Jones, James R. Apgar, Mengmeng Wang, Jeffrey C Kurz, Jason Wade, Nicole Piche-Nicholas, Amy King
Implementation of in vitro assays that correlate with in vivo human pharmacokinetics (PK) would provide desirable preclinical tools for the early selection of therapeutic monoclonal antibody (mAb) candidates with minimal non-target-related PK risk. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5432fe3b98ffabab0f414ed12b150d
https://europepmc.org/articles/PMC5825195/
https://europepmc.org/articles/PMC5825195/
Publikováno v:
Journal of Immunological Methods. 474:112642
Proper evaluation of immunogenicity during clinical development of biotherapeutics is a major challenge to bioanalytical scientists, in part due to matrix interference in anti-drug antibody (ADA) and neutralizing antibody (NAB) assays. If not address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd938ebbd5ee2eec4ad8f7ae365892f
https://doi.org/10.1016/j.jim.2019.112642
https://doi.org/10.1016/j.jim.2019.112642
Autor:
Aili Cheng, Robert J Polzer, Fei Hua, Martin E. Dowty, Lindsay B. Avery, Hannah M. Jones, Alison Joyce, Yiqun Zhang, Hendrik Neubert, Mania Kavosi, Yao-Yun Fan, Minlei Zhang, Mengmeng Wang, Jeffrey C Kurz, Denise O'Hara
Publikováno v:
mAbs. 8(6)
Therapeutic antibodies continue to develop as an emerging drug class, with a need for preclinical tools to better predict in vivo characteristics. Transgenic mice expressing human neonatal Fc receptor (hFcRn) have potential as a preclinical pharmacok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f9d287258f7be2850dbc301f241795
https://pubmed.ncbi.nlm.nih.gov/27232760
https://pubmed.ncbi.nlm.nih.gov/27232760
Publikováno v:
Analytical and Bioanalytical Chemistry. 401:2855-2863
Novel magnetic multi-walled carbon nanotubes@Fe(3)O(4) molecularly imprinted polymers (MWNTs@Fe(3)O(4)-MIPs) intended for bovine serum albumin (BSA) recognition were successfully developed. The MWNTs@Fe(3)O(4)-MIPs were characterized with scanning el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf7f2693f285094b7f9d86f972327b9
https://doi.org/10.1007/s00216-011-5373-9
https://doi.org/10.1007/s00216-011-5373-9
Publikováno v:
Proceedings of the 2016 International Conference on Communications, Information Management and Network Security.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaeba4a216c837c09dea5e6e7ff7ddc1
https://doi.org/10.2991/cimns-16.2016.58
https://doi.org/10.2991/cimns-16.2016.58
Publikováno v:
Proceedings of the 2016 International Conference on Communications, Information Management and Network Security.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a777de8949fef84461d5032322a7fcd
https://doi.org/10.2991/cimns-16.2016.28
https://doi.org/10.2991/cimns-16.2016.28
Publikováno v:
Proceedings of the 2016 International Conference on Communications, Information Management and Network Security.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db549d659800d4c5bf8929f1706d9dfb
https://doi.org/10.2991/cimns-16.2016.30
https://doi.org/10.2991/cimns-16.2016.30
Publikováno v:
Molecular and Cellular Neuroscience. 27:477-488
We have shown previously that components of the extracellular matrix (ECM) modulate neuronal development. Here, we searched for additional ECM elements that might play roles in retinal histogenesis and identified a secreted glycoprotein that is heavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3ff713353d5c2e8ece3dc2b82d9ea9
https://doi.org/10.1016/j.mcn.2004.08.003
https://doi.org/10.1016/j.mcn.2004.08.003