Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Minjun Li"'
Autor:
Feng Yu, Ke Liu, Huan Zhou, Minjun Li, Huating Kong, Kunhao Zhang, Xingya Wang, Weiwei Wang, Qin Xu, Qiangyan Pan, Zhijun Wang, Qisheng Wang
Publikováno v:
Journal of Synchrotron Radiation, Vol 31, Iss 2, Pp 378-384 (2024)
An integrated computer software system for macromolecular crystallography (MX) data collection at the BL02U1 and BL10U2 beamlines of the Shanghai Synchrotron Radiation Facility is described. The system, Finback, implements a set of features designed
Externí odkaz:
https://doaj.org/article/6690ff21489a44ffa3130cb7cfa391be
Autor:
Xiangrui Jiang, Haixia Su, Weijuan Shang, Feng Zhou, Yan Zhang, Wenfeng Zhao, Qiumeng Zhang, Hang Xie, Lei Jiang, Tianqing Nie, Feipu Yang, Muya Xiong, Xiaoxing Huang, Minjun Li, Ping Chen, Shaoping Peng, Gengfu Xiao, Hualiang Jiang, Renhong Tang, Leike Zhang, Jingshan Shen, Yechun Xu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The persistent pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants accentuates the great demand for developing effective therapeutic agents. Here, we report
Externí odkaz:
https://doaj.org/article/a28e5c09138247129c790be1234763fd
Autor:
Chenyu Zhang, Qin Xu, Weiwei Wang, Miao Liang, Li Yu, Minjun Li, Zhimin Zhu, Liqing Huang, Qianhui Li, Feng Yu, Yuzhu Wang, Huan Zhou, Qisheng Wang
Publikováno v:
Crystals, Vol 14, Iss 2, p 199 (2024)
To resolve photons hungry for weak diffraction samples by the crystallographic method, a double-multilayer monochromator (DMM) was employed on an undulator beamline (BL17UM) at the Shanghai Synchrotron Radiation Facility (SSRF) to provide a focused s
Externí odkaz:
https://doaj.org/article/ca34589baec345d9899293d8e8a9caab
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 7, Iss 11, Pp 1890-1892 (2022)
Eleutherococcus nodiflorus (Dunn) S. Y. Hu is a momentous medicinal plant belonging to the Araliaceae family. In the current investigation, we determined the complete chloroplast genome of E. nodiflorus and analyzed the phylogenetic relationship amon
Externí odkaz:
https://doaj.org/article/0b2cc4f7a5874ec08d100e589bf75449
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9587 (2023)
The current understanding of the prognostic significance of natural killer (NK) cells and their tumor microenvironment (TME) in hepatocellular carcinoma (HCC) is limited. Thus, we screened for NK-cell-related genes by single-cell transcriptome data a
Externí odkaz:
https://doaj.org/article/76012a0cab3c40ef974dc6254b0db850
Autor:
Qian Wang, Guofeng Chen, Jian He, Jiameng Li, Muya Xiong, Haixia Su, Minjun Li, Hangchen Hu, Yechun Xu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8633 (2023)
The papain-like protease (PLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a critical role in the proteolytic processing of viral polyproteins and the dysregulation of the host immune response, providing a promising therap
Externí odkaz:
https://doaj.org/article/c9e06c42a91e4913af00a53646bcf667
Autor:
Haixia Su, Sheng Yao, Wenfeng Zhao, Yumin Zhang, Jia Liu, Qiang Shao, Qingxing Wang, Minjun Li, Hang Xie, Weijuan Shang, Changqiang Ke, Lu Feng, Xiangrui Jiang, Jingshan Shen, Gengfu Xiao, Hualiang Jiang, Leike Zhang, Yang Ye, Yechun Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
SARS-CoV-2 3CL protease (3CLpro) is essential for coronavirus replication and of great interest as an antiviral drug target. Here, the authors show that the naturally occurring flavonoid myricetin is a non-peptidomimetic and covalent inhibitor of 3CL
Externí odkaz:
https://doaj.org/article/ff68234682c746f3aa209aef3785fbf8
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
Autor:
Jue Xiang Wang, Mark W. Irvine, Erica S. Burnell, Kiran Sapkota, Robert J. Thatcher, Minjun Li, Noriko Simorowski, Arturas Volianskis, Graham L. Collingridge, Daniel T. Monaghan, David E. Jane, Hiro Furukawa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Selectively inhibiting N-Methyl-D-aspartate receptors (NMDARs) containing the GluN2C/2D subunits has been challenging. Here, using electrophysiology and X-ray crystallography, authors show that compounds UBP791 and UBP1700 show over 40- and 50-fold s
Externí odkaz:
https://doaj.org/article/9cf4ff26eb1b4740b5b19c5f54918691
Autor:
Qin Xu, Huan Zhou, Minjun Li, Weiwei Wang, Mengxue Xu, Zhimin Zhu, Chenyu Zhang, Qisheng Wang, Feng Yu, Jianhua He
Publikováno v:
Crystals, Vol 12, Iss 4, p 468 (2022)
MMACHC is an essential protein for the body to metabolise vitamin B12, and its deficiency will cause cblC-type methylmalonic aciduria and homocystinuria. MMACHC can interact with cyanocobalamin (a type of vitamin B12) cofactor and plays an important
Externí odkaz:
https://doaj.org/article/c3f6e28166754d3da434f661a0f50130
Structural insights into the mechanism for recognizing substrate of the cytochrome P450 enzyme TxtE.
Autor:
Feng Yu, Minjun Li, Chunyan Xu, Zhijun Wang, Huan Zhou, Min Yang, Yaxing Chen, Lin Tang, Jianhua He
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81526 (2013)
Thaxtomins, a family of phytotoxins produced by Streptomyces spp., can cause dramatic plant cell hypertrophy and seedling stunting. Thaxtomin A is the dominant form from Streptomyces scabies and has demonstrated herbicidal action. TxtE, a cytochrome
Externí odkaz:
https://doaj.org/article/76a2423956b645d89822cfb367827cc1