Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Minjun, Chen"'
Autor:
Shensuo Li, Yuzhong Peng, Minjun Chen, Yankun Zhao, Yi Xiong, Jianfeng Li, Peng Luo, Haitao Wang, Fei Zhao, Qi Zhao, Yanru Cui, Sujun Chen, Jian-Guo Zhou, Shixiang Wang
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract The continuous generation of multi-omics and phenotype data is propelling advancements in precision oncology. UCSCXenaShiny was developed as an interactive tool for exploring thousands of cancer datasets available on UCSC Xena. However, its
Externí odkaz:
https://doaj.org/article/8e4c2b78349f478aa823decbe366adb5
Autor:
Minjun Chen, Yue Wu, Byron Wingerd, Zhichao Liu, Joshua Xu, Shraddha Thakkar, Thomas J. Pedersen, Tom Donnelly, Nicholas Mann, Weida Tong, Russell D. Wolfinger, Wenjun Bao
Publikováno v:
Frontiers in Artificial Intelligence, Vol 7 (2024)
IntroductionRegulatory agencies generate a vast amount of textual data in the review process. For example, drug labeling serves as a valuable resource for regulatory agencies, such as U.S. Food and Drug Administration (FDA) and Europe Medical Agency
Externí odkaz:
https://doaj.org/article/a13d69361f034786a1042a23c1a15837
Autor:
Can Chen MS, Minjun Chen MS, Yuju Bai MS, Yajun Li PhD, Jie Peng PhD, Biao Yao MS, Jiangping Feng BS, Jian-Guo Zhou PhD, Hu Ma PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 23 (2024)
Background Cadonilimab (AK104) is a bispecific IgG-single-chain Fv fragment (ScFv) antibody that binds to PD-1 and CTLA-4. Cadonilimab has shown encouraging anti-tumour activity and a favourable safety profile in several tumour types. In second-line
Externí odkaz:
https://doaj.org/article/715ac5fd69c648feadd1463e6244c0bd
Autor:
Fahad Mostafa, Minjun Chen
Publikováno v:
Frontiers in Toxicology, Vol 5 (2024)
Drug-induced liver injury (DILI) is a severe adverse reaction caused by drugs and may result in acute liver failure and even death. Many efforts have centered on mitigating risks associated with potential DILI in humans. Among these, quantitative str
Externí odkaz:
https://doaj.org/article/b1333d98410d4084bf676b1dbcc397a6
Autor:
Qi Zhao, Jianfeng Li, Xuejun Li, Jian-Guo Zhou, Benjamin Frey, Hu Ma, Haitao Wang, Peng Luo, Markus Hecht, Udo Gaipl, Shixiang Wang, Yi Xiong, Yihao Zhang, Minjun Chen, Yung-Hung Luo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Immunotherapies targeting immune checkpoints have gained increasing attention in cancer treatment, emphasizing the need for predictive biomarkers. Circular RNAs (circRNAs) have emerged as critical regulators of tumor immunity, particularly
Externí odkaz:
https://doaj.org/article/c918fd42f1644b83b574fa49efdc8fdc
Publikováno v:
Toxics, Vol 12, Iss 6, p 385 (2024)
Drug-induced liver injury (DILI) poses a significant challenge for the pharmaceutical industry and regulatory bodies. Despite extensive toxicological research aimed at mitigating DILI risk, the effectiveness of these techniques in predicting DILI in
Externí odkaz:
https://doaj.org/article/c8bc092727c74b13b7c24e38c00fd65e
Autor:
Minjun Chen, Ksenija R. Kumrić, Conner Thacker, Radivoje Prodanović, Guido Bolognesi, Goran T. Vladisavljević
Publikováno v:
Gels, Vol 9, Iss 11, p 849 (2023)
Monodispersed polyethylene glycol diacrylate (PEGDA)/acrylic acid (AA) microgels with a tuneable negative charge and macroporous internal structure have been produced using a Lego-inspired droplet microfluidic device. The surface charge of microgels
Externí odkaz:
https://doaj.org/article/b638cc48f2c24cbba00867170e4be2e1
Autor:
Hubert Dirven, Gunn E. Vist, Sricharan Bandhakavi, Jyotsna Mehta, Seneca E. Fitch, Pandora Pound, Rebecca Ram, Breanne Kincaid, Cathalijn H. C. Leenaars, Minjun Chen, Robert A. Wright, Katya Tsaioun
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Drug-induced liver injury (DILI) causes one in three market withdrawals due to adverse drug reactions, causing preventable human suffering and massive financial loss. We applied evidence-based methods to investigate the role of preclinical s
Externí odkaz:
https://doaj.org/article/7f8d336a0d9f49f98f99309991efd57e
Publikováno v:
Frontiers in Artificial Intelligence, Vol 4 (2021)
Background & Aims: The United States Food and Drug Administration (FDA) regulates a broad range of consumer products, which account for about 25% of the United States market. The FDA regulatory activities often involve producing and reading of a larg
Externí odkaz:
https://doaj.org/article/0420db0639784d25bd83f7d46c097387
Publikováno v:
Molecules, Vol 27, Iss 13, p 4013 (2022)
Poly(ethylene glycol) diacrylate (PEGDA) microgels with tuneable size and porosity find applications as extracellular matrix mimics for tissue-engineering scaffolds, biosensors, and drug carriers. Monodispersed PEGDA microgels were produced by modula
Externí odkaz:
https://doaj.org/article/efa5dde27b2b495da885de5836e0f32c