Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Minji Seung"'
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Akademický článek
Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis
Autor: Archana Vijayakumar, Ayse Okesli‐Armlovich, Ting Wang, Isabel Olson, Minji Seung, Saritha Kusam, David Hollenback, Sangeetha Mahadevan, Bruno Marchand, Maria Toteva, David G. Breckenridge, James L. Trevaskis, Jamie Bates
Publikováno v: Hepatology Communications, Vol 6, Iss 9, Pp 2298-2309 (2022)
Abstract Dysregulated hepatocyte lipid metabolism is a hallmark of hepatic lipotoxicity and contributes to the pathogenesis of nonalcoholic steatohepatitis (NASH). Acetyl CoA carboxylase (ACC) inhibitors decrease hepatocyte lipotoxicity by inhibiting
Externí odkaz: https://doaj.org/article/fcccdbbbcc8c483fa465bc4bd08eb25c
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Cholix protein domain I functions as a carrier element for efficient apical to basal epithelial transcytosis
Autor: Randall J. Mrsny, Alistair Taverner, Weijun Feng, Keyi Liu, Tom Hunter, Khushdeep Mangat, Elbert Seto, Sally Postlethwaite, Lisa Song, Apurva Chandalia, Mazi Saberi, Floriane Laurent, Aatif Alam, Minji Seung, Julia D. Mackay
Publikováno v: Tissue Barriers
Cholix (Chx) is expressed by the intestinal pathogen Vibrio cholerae as a single chain of 634 amino acids (~70.7 kDa protein) that folds into three distinct domains, with elements of the second and third domains being involved in accessing the cytopl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbed07e34e5840d3e5e8f1a00fc06df
https://doi.org/10.1080/21688370.2019.1710429
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Regulation of Mitochondrial Morphology by Positive Feedback Interaction Between PKCδ and Drp1 in Vascular Smooth Muscle Cell
Autor: Ki-Chul Hwang, Sun M. Han, Ina Yun, Hyang-Hee Seo, Jiyun Lee, Seahyoung Lee, Jun-Hee Park, Chang Yeon Lee, Se-Yeon Lee, Onju Ham, Eunhyun Choi, Minji Seung, Soyeon Lim
Publikováno v: Journal of Cellular Biochemistry. 116:648-660
Dynamin-related protein-1 (Drp1) plays a critical role in mitochondrial fission which allows cell proliferation and Mdivi-1, a specific small molecule Drp1 inhibitor, is revealed to attenuate proliferation. However, few molecular mechanisms-related t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::307aadb7df1a6baecb8b30e4c356118f
https://doi.org/10.1002/jcb.25016
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Effect of Hypoxic Paracrine Media on Calcium-Regulatory Proteins in Infarcted Rat Myocardium
Autor: Byeong-Wook Song, Minji Seung, Moon Hyoung Lee, Hye Jin Hwang
Publikováno v: Korean Circulation Journal
BACKGROUND AND OBJECTIVES An increase in intracellular calcium concentration due to loss of Ca(2+) homeostasis triggers arrhythmia or cardiac cell death in the heart. Paracrine factors released from stem cells have beneficial cardioprotective effects
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3795a8574da262796f07a5732b455e03
http://europepmc.org/articles/PMC3905111
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Regulation of mitochondrial morphology by positive feedback interaction between PKCδ and Drp1 in vascular smooth muscle cell
Autor: Soyeon, Lim, Se-Yeon, Lee, Hyang-Hee, Seo, Onju, Ham, Changyeon, Lee, Jun-Hee, Park, Jiyun, Lee, Minji, Seung, Ina, Yun, Sun M, Han, Seahyoung, Lee, Eunhyun, Choi, Ki-Chul, Hwang
Publikováno v: Journal of cellular biochemistry. 116(4)
Dynamin-related protein-1 (Drp1) plays a critical role in mitochondrial fission which allows cell proliferation and Mdivi-1, a specific small molecule Drp1 inhibitor, is revealed to attenuate proliferation. However, few molecular mechanisms-related t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c9803356c3cea1408733706f355da9c
https://pubmed.ncbi.nlm.nih.gov/25399916
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Modulation of Fas-Fas Ligand Interaction Rehabilitates Hypoxia-Induced Apoptosis of Mesenchymal Stem Cells in Ischemic Myocardium Niche
Autor: Ki-Chul Hwang, Jiyun Lee, Minji Seung, Yangsoo Jang, Se-Yeon Lee, Jun-Hee Park, Chang Youn Lee, Hyang Hee Seo, Onju Ham, Il-Kwon Kim, Byeong-Wook Song, Eunhyun Choi, Min Ji Cha
Publikováno v: Cell Transplantation, Vol 24 (2015)
Mesenchymal stem cells (MSCs) have the potential to repair and regenerate ischemic heart tissue; however, the poor viability of transplanted MSCs in the ischemic region is a major obstacle to their therapeutic use. This cell death is caused by Fas an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621d195fe7b27cc6f43ddd56e45fabd6
https://pubmed.ncbi.nlm.nih.gov/24823387
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Abstract 173: MicroRNA-365 Inhibits the Proliferation of Vascular Smooth Muscle Cells by Targeting Cyclin D1
Autor: Myung-Hyun Kim, Onju Ham, Se-Yeon Lee, Eunmi Choi, Chang Yeon Lee, Jun-Hee Park, Jiyun Lee, Hyang-Hee Seo, Minji Seung, Eunhyun Choi, Pil-Ki Min, Ki-Chul Hwang, Hyuck Moon Kwon
Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Background: Abnormal proliferation of vascular smooth muscle cells (VSMCs) is a common feature of disease progression in atherosclerosis. Cell proliferation is regulated by cell cycle regulatory proteins. MicroRNAs (miRNAs) have been reported to act
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::275fbdf9d41b2016a0c744b6e7bc62b8
https://doi.org/10.1161/atvb.34.suppl_1.173
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