Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mini Manchanda"'
Autor:
Kuang‐Yung Lee, Moyi Li, Mini Manchanda, Ranjan Batra, Konstantinos Charizanis, Apoorva Mohan, Sonisha A. Warren, Christopher M. Chamberlain, Dustin Finn, Hannah Hong, Hassan Ashraf, Hideko Kasahara, Laura P. W. Ranum, Maurice S. Swanson
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 12, Pp 1887-1900 (2013)
Abstract Myotonic dystrophy (DM) is a multi‐systemic disease that impacts cardiac and skeletal muscle as well as the central nervous system (CNS). DM is unusual because it is an RNA‐mediated disorder due to the expression of toxic microsatellite
Externí odkaz:
https://doaj.org/article/e6ecfc7eb11f40d5b72afc0761cf559b
Autor:
Viet Nhan, Bharath Bharadwaj, Tristan Nater, Matthew Brentnall, Bin Wu, Peter LoCoco, Lauren Abutin, Mini Manchanda, Jay Shaw, Foram Rathi, Aparna R. Aiyer
Publikováno v:
Cancer Research. 80:772-772
Background: Cholangiocarcinoma (CC) is an aggressive bile-duct cancer that affects 8000 people per year in the US. This silent disease manifests symptoms only in advanced stages, resulting in a 5-year overall survival rate of < 10%. Mutations in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7efbf4460de619541ecff763b0fda6
https://doi.org/10.1158/1538-7445.am2020-772
https://doi.org/10.1158/1538-7445.am2020-772
Autor:
Hassan Ashraf, Mini Manchanda, Apoorva Mohan, Konstantinos Charizanis, Christopher M. Chamberlain, Ranjan Batra, Moyi Li, Hannah Hong, Dustin J. Finn, Maurice S. Swanson, Kuang-Yung Lee, Laura P.W. Ranum, Hideko Kasahara, Sonisha Warren
Publikováno v:
EMBO Molecular Medicine
Myotonic dystrophy (DM) is a multi‐systemic disease that impacts cardiac and skeletal muscle as well as the central nervous system (CNS). DM is unusual because it is an RNA‐mediated disorder due to the expression of toxic microsatellite expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7308930cc90f8e12150f427d8f87222f
https://doi.org/10.1002/emmm.201303275
https://doi.org/10.1002/emmm.201303275
Autor:
Mini Manchanda, Arun Kumar, Shantanu Sengupta, Kausik Chakraborty, Abhay Sharma, Shuvadeep Maity, Neeru Saini, Lijo John
Publikováno v:
Journal of Biological Chemistry. 286:21779-21795
An elevated level of homocysteine, a thiol amino acid, is associated with various complex disorders. The cellular effects of homocysteine and its precursors S-adenosylhomocysteine (AdoHcy) and S-adenosylmethionine (AdoMet) are, however, poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d6ac26780e6474a2ff759ecde8ed9a
https://doi.org/10.1074/jbc.m111.228072
https://doi.org/10.1074/jbc.m111.228072
Publikováno v:
RNA biology. 12(6)
Alternative pre-mRNA processing greatly increases the coding capacity of the human genome and regulatory factors involved in RNA processing play critical roles in tissue development and maintenance. Indeed, abnormal functions of RNA processing factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9d3de9fcf73a436887a6ad7142cd48
https://pubmed.ncbi.nlm.nih.gov/25892335
https://pubmed.ncbi.nlm.nih.gov/25892335
Autor:
Marianne Goodwin, Moyi Li, Dustin J. Finn, Chaolin Zhang, Maurice S. Swanson, Apoorva Mohan, Konstantinos Charizanis, Charles A. Thornton, Krzysztof Sobczak, Mini Manchanda, Ranjan Batra
Publikováno v:
Molecular cell. 56(2)
Inhibition of muscleblind-like (MBNL) activity due to sequestration by microsatellite expansion RNAs is a major pathogenic event in the RNA-mediated disease myotonic dystrophy (DM). Although MBNL1 and MBNL2 bind to nascent transcripts to regulate alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4c450248b55c379e7287a2ca683683
https://pubmed.ncbi.nlm.nih.gov/25263597
https://pubmed.ncbi.nlm.nih.gov/25263597
Autor:
Varsha Srivastava, Gobardhan Das, Rupak Singla, Mini Manchanda, Krishnamurthy Natarajan, Shashank Gupta, Digamber Behera
Publikováno v:
The Journal of biological chemistry. 284(38)
A hallmark of protective immunity during Mycobacterium tuberculosis (M. tb) infection is the regulated secretion of pro-inflammatory and regulatory cytokines. Suppressors of Cytokine Signaling (SOCS) are key regulators of cytokine secretion and funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b71f74ecba24add13d146e43c677301
https://pubmed.ncbi.nlm.nih.gov/19617348
https://pubmed.ncbi.nlm.nih.gov/19617348