Herpes zoster mRNA vaccine induces superior vaccine immunity over licensed vaccine in mice and rhesus macaques

Autor: Lulu Huang, Tongyi Zhao, Weijun Zhao, Andong Shao, Huajun Zhao, Wenxuan Ma, Yingfei Gong, Xianhuan Zeng, Changzhen Weng, Lingling Bu, Zhenhua Di, Shiyu Sun, Qinsheng Dai, Minhui Sun, Limei Wang, Zhenguang Liu, Leilei Shi, Jiesen Hu, Shentong Fang, Cheng Zhang, Jian Zhang, Guan Wang, Karin Loré, Yong Yang, Ang Lin

Publikováno v: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

ABSTRACTHerpes zoster remains an important global health issue and mainly occurs in aged and immunocompromised individuals with an early exposure history to Varicella Zoster Virus (VZV). Although the licensed vaccine Shingrix has remarkably high effi

Externí odkaz: https://doaj.org/article/10860985a51042b89c1e33835ed869db

An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome

Autor: Johanna Tüshaus, Dmitrij Frishman, Minhui Su, Gökhan Güner, Stefan F. Lichtenthaler, Mikael Simons, Georg Jocher, Sabina Tahirovic, Jan Zaucha, Laura Sebastian Monasor, Stephan A. Müller, Evans Kataka

Publikováno v: The EMBO journal 39(20), e105693 (2020). doi:10.15252/embj.2020105693
The EMBO Journal

To understand how cells communicate in the nervous system, it is essential to define their secretome, which is challenging for primary cells because of large cell numbers being required. Here, we miniaturized secretome analysis by developing the “h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e431959c6cfdf27737f316819ef48ffc
https://pub.dzne.de/record/154360

Construction of self-powered cytosensing device based on ZnO nanodisks@g-C3N4 quantum dots and application in the detection of CCRF-CEM cells

Autor: Weihong Tan, Qin Wei, Cheng Cui, Minhui Su, Yaoguang Wang, Xuehui Pang

Publikováno v: Nano Energy. 46:101-109

We herein report a self-powered and renewable cytosensing device based on ZnO nanodisks(NDs)@g-C3N4 quantum dots. The device features enhanced photoelectrochemical (PEC) activity compared to ZnO NDs or g-C3N4 QDs alone. The enhanced PEC ability is at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57f66339ac5c20a3441c413858e51a31
https://doi.org/10.1016/j.nanoen.2018.01.018

Bufei Qingyu Granules Inhibit the Development of Systemic Sclerosis via Notch-1/Jagged-2 Signaling Pathway

Autor: Xue-jun Zhu, Bingchen Ouyang, Xian Qian, Feng Guo, Xiaoyu Wu, Fang Tian, Minhui Su, Jianmei Chen, Hua Chen

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2019 (2019)
Evidence-based Complementary and Alternative Medicine : eCAM

Systemic sclerosis (SSc) is a rare chronic autoimmune disorder, mainly characterized by skin sclerosis. In this study, Bufei Qingyu Granules (BQG), a Chinese herbal formula, was used to treat SSc. To better understand the effects and molecular mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b16dce2a024d5a076ccd19d13bd272e

Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome

Autor: Caroline G. Bergner, Minhui Su, Dirk Fitzner, Michal A. Surma, Horst Penkert, Mikael Simons, Christian Klose, Matthias Mann, Jakob M. Bader, Marie-Theres Weil

Publikováno v: Fitzner, D, Bader, J M, Penkert, H, Bergner, C G, Su, M, Weil, M-T, Surma, M A, Mann, M, Klose, C & Simons, M 2020, ' Cell-Type-and Brain-Region-Resolved Mouse Brain Lipidome ', Cell Reports, vol. 32, 108132 . https://doi.org/10.1016/j.celrep.2020.108132
Cell Reports
Cell reports 32(11), 108132-(2020). doi:10.1016/j.celrep.2020.108132

Gene and protein expression data provide useful resources for understanding brain function, but little is known about the lipid composition of the brain. Here, we perform quantitative shotgun lipidomics, which enables a cell-type-resolved assessment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdc999693573fd308506058c50240bf
https://doi.org/10.1016/j.celrep.2020.108132