Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Minhtran C. Ngo"'
1
Identification of protective T-cell antigens for smallpox vaccines
Autor: Ann M. Leen, Miki Ando, Cliona M. Rooney, Jun Ando, Minhtran C. Ngo
Publikováno v: Cytotherapy
Background aims E3L is an immediate-early protein of vaccinia virus (VV) that is detected within 0.5 h of infection, potentially before the many immune evasion genes of vaccinia can exert their protective effects. E3L is highly conserved among orthop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2588cb3d89a36fceaddb8bd2ed4a79c
https://pubmed.ncbi.nlm.nih.gov/32747299
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2
Systematic review of measurement tools to assess surgeons' intraoperative cognitive workload
Autor: Marko T. Boskovski, Marco A. Zenati, Minhtran C. Ngo-Howard, Roger D. Dias, Steven Yule
Publikováno v: British Journal of Surgery. 105:491-501
Background Surgeons in the operating theatre deal constantly with high-demand tasks that require simultaneous processing of a large amount of information. In certain situations, high cognitive load occurs, which may impact negatively on a surgeon's p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a509ae11043c040ed9670d3fd5655097
https://doi.org/10.1002/bjs.10795
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3
Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells
Autor: Paul R. Kinchington, Ann M. Leen, Miyuki Tanaka, Jun Ando, Haruko Tashiro, Natasha Lapteva, Birju Mehta, Cliona M. Rooney, Bilal Omer, Gianpietro Dotti, Minhtran C. Ngo, Claudia Rossig
Publikováno v: Clinical Cancer Research. 23:3499-3509
Purpose: The multiple mechanisms used by solid tumors to suppress tumor-specific immune responses are a major barrier to the success of adoptively transferred tumor-specific T cells. As viruses induce potent innate and adaptive immune responses, we h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622530108391b352aa3b3a73734713bc
https://doi.org/10.1158/1078-0432.ccr-16-2138
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5
Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications
Autor: Susann Szmania, Juan F. Vera, Dario Campana, Natalia Lapteva, Elaine Coustan-Smith, April G. Durett, Amberly Moreno-Bost, Minhtran C. Ngo, Jiali Sun, Leslie L. Huye, Adrian P. Gee, Jun Ando, Lisa Rollins, Frits Vanrhee, Cliona M. Rooney, Jian Fang, Zhuyong Mei, Tarun K. Garg, Varada Dandekar, Kimberley Jackson
Publikováno v: Cytotherapy. 14:1131-1143
Interest in natural killer (NK) cell-based immunotherapy has resurged since new protocols for the purification and expansion of large numbers of clinical-grade cells have become available.We have successfully adapted a previously described NK expansi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7f76f3c0b4608cbc05773776cd59f5
https://doi.org/10.3109/14653249.2012.700767
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6
Accelerated Production of Antigen-specific T Cells for Preclinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex)
Autor: John R. Wilson, Gianpietro Dotti, Uluhan Sili, Minhtran C. Ngo, Cliona M. Rooney, Hao Liu, Ulrike Gerdemann, Ann M. Leen, Helen E. Heslop, Juan F. Vera, Lara J. Brenner
Publikováno v: Journal of Immunotherapy. 33:305-315
The clinical manufacture of antigen-specific cytotoxic T lymphocytes (CTLs) for adoptive immunotherapy is limited by the complexity and time required to produce large numbers with the desired function and specificity. The culture conditions required
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9602a1a86a258edea841be58ee6df5b1
https://doi.org/10.1097/cji.0b013e3181c0c3cb
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7
Broadly-specific Cytotoxic T Cells Targeting Multiple HIV Antigens Are Expanded From HIV+ Patients: Implications for Immunotherapy
Autor: Carolina Garrido, Joann D. Kuruc, Paul Castillo-Caro, Sharon Lam, Cliona M. Rooney, David M. Margolis, Julia Sung, Conrad Russell Y. Cruz, Minhtran C. Ngo, Catherine M. Bollard, Nancie M. Archin
Antiretroviral therapy (ART) is unable to eradicate human immunodeficiency virus type 1 (HIV-1) infection. Therefore, there is an urgent need to develop novel therapies for this disease to augment anti-HIV immunity. T cell therapy is appealing in thi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089f82bad1b3d3520819d82f4a01fddd
https://europepmc.org/articles/PMC4445615/
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8
Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity
Autor: Ann M. Leen, Martha P. Mims, Cliona M. Rooney, Jun Ando, Helen E. Heslop, Minhtran C. Ngo, Juan F. Vera, Amelia Min-Venditti, Catherine M. Bollard, Stephen Gottschalk, Natalia Lapteva, Sravya Ennamuri
Publikováno v: Journal of immunotherapy (Hagerstown, Md. : 1997). 37(4)
Antigen-specific T cells provide a therapy for cancer that is highly specific, self-replicating, and potentially devoid of toxicity. Ideally, tumor-specific T cells should recognize multiple epitopes on multiple antigens to prevent tumor immune escap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c6b90855d2b6cba0559777ad6316e1
https://pubmed.ncbi.nlm.nih.gov/24714353
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9
Ex vivo gene transfer for improved adoptive immunotherapy of cancer
Autor: Cliona M. Rooney, Jeffrey M. Howard, Helen E. Heslop, Minhtran C. Ngo
Adoptive immunotherapy is an appealing approach to cancer treatment, with the potential for more precise targeting and reduced toxicity. While early clinical trial data using adoptive T cells against post-transplant virus-associated hematologic malig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01787b58f6a2ee52202aac4629dc9b14
https://europepmc.org/articles/PMC3095061/
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10
Regulation of ventral midbrain patterning by Hedgehog signaling
Autor: Minhtran C. Ngo, Seema Agarwala, Roy D. Bayly, Galina V. Aglyamova
Publikováno v: Development (Cambridge, England). 134(11)
In the developing ventral midbrain, the signaling molecule sonic hedgehog(SHH) is sufficient to specify a striped pattern of cell fates (midbrain arcs). Here, we asked whether and precisely how hedgehog (HH) signaling might be necessary for ventral m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f7581362771fb8f252ce80f35d3687
https://pubmed.ncbi.nlm.nih.gov/17507412
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