Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Minhtran C. Ngo"'
Publikováno v:
Cytotherapy
Background aims E3L is an immediate-early protein of vaccinia virus (VV) that is detected within 0.5 h of infection, potentially before the many immune evasion genes of vaccinia can exert their protective effects. E3L is highly conserved among orthop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2588cb3d89a36fceaddb8bd2ed4a79c
https://pubmed.ncbi.nlm.nih.gov/32747299
https://pubmed.ncbi.nlm.nih.gov/32747299
Publikováno v:
British Journal of Surgery. 105:491-501
Background Surgeons in the operating theatre deal constantly with high-demand tasks that require simultaneous processing of a large amount of information. In certain situations, high cognitive load occurs, which may impact negatively on a surgeon's p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a509ae11043c040ed9670d3fd5655097
https://doi.org/10.1002/bjs.10795
https://doi.org/10.1002/bjs.10795
Autor:
Paul R. Kinchington, Ann M. Leen, Miyuki Tanaka, Jun Ando, Haruko Tashiro, Natasha Lapteva, Birju Mehta, Cliona M. Rooney, Bilal Omer, Gianpietro Dotti, Minhtran C. Ngo, Claudia Rossig
Publikováno v:
Clinical Cancer Research. 23:3499-3509
Purpose: The multiple mechanisms used by solid tumors to suppress tumor-specific immune responses are a major barrier to the success of adoptively transferred tumor-specific T cells. As viruses induce potent innate and adaptive immune responses, we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622530108391b352aa3b3a73734713bc
https://doi.org/10.1158/1078-0432.ccr-16-2138
https://doi.org/10.1158/1078-0432.ccr-16-2138
Autor:
Manijeh Daneshmand, Richard H. Patt, Tae-Ho Hwang, Theresa Hickman, John C. Bell, Minhtran C. Ngo, Hyun Cheol Chung, Leyo Ruo, Steven C. Rose, Kara S DuBois, Anne Moon, Yeon Sook Lee, Caroline J. Breitbach, Chang Won Kim, Mong Cho, Tony R. Reid, Byung Geon Rhee, Lara Longpre, Cliona M. Rooney, Riccardo Lencioni, Ho Yeong Lim, James M. Burke, David H. Kirn, Mark Bloomston, Jeong Heo, Mi Kyeong Kim
Publikováno v:
Nature Medicine. 19:329-336
Oncolytic viruses and active immunotherapeutics have complementary mechanisms of action (MOA) that are both self amplifying in tumors, yet the impact of dose on subject outcome is unclear. JX-594 (Pexa-Vec) is an oncolytic and immunotherapeutic vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93121785708af4362ae77e7d2c3611a3
https://doi.org/10.1038/nm.3089
https://doi.org/10.1038/nm.3089
Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications
Autor:
Susann Szmania, Juan F. Vera, Dario Campana, Natalia Lapteva, Elaine Coustan-Smith, April G. Durett, Amberly Moreno-Bost, Minhtran C. Ngo, Jiali Sun, Leslie L. Huye, Adrian P. Gee, Jun Ando, Lisa Rollins, Frits Vanrhee, Cliona M. Rooney, Jian Fang, Zhuyong Mei, Tarun K. Garg, Varada Dandekar, Kimberley Jackson
Publikováno v:
Cytotherapy. 14:1131-1143
Interest in natural killer (NK) cell-based immunotherapy has resurged since new protocols for the purification and expansion of large numbers of clinical-grade cells have become available.We have successfully adapted a previously described NK expansi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7f76f3c0b4608cbc05773776cd59f5
https://doi.org/10.3109/14653249.2012.700767
https://doi.org/10.3109/14653249.2012.700767
Autor:
John R. Wilson, Gianpietro Dotti, Uluhan Sili, Minhtran C. Ngo, Cliona M. Rooney, Hao Liu, Ulrike Gerdemann, Ann M. Leen, Helen E. Heslop, Juan F. Vera, Lara J. Brenner
Publikováno v:
Journal of Immunotherapy. 33:305-315
The clinical manufacture of antigen-specific cytotoxic T lymphocytes (CTLs) for adoptive immunotherapy is limited by the complexity and time required to produce large numbers with the desired function and specificity. The culture conditions required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9602a1a86a258edea841be58ee6df5b1
https://doi.org/10.1097/cji.0b013e3181c0c3cb
https://doi.org/10.1097/cji.0b013e3181c0c3cb
Autor:
Carolina Garrido, Joann D. Kuruc, Paul Castillo-Caro, Sharon Lam, Cliona M. Rooney, David M. Margolis, Julia Sung, Conrad Russell Y. Cruz, Minhtran C. Ngo, Catherine M. Bollard, Nancie M. Archin
Antiretroviral therapy (ART) is unable to eradicate human immunodeficiency virus type 1 (HIV-1) infection. Therefore, there is an urgent need to develop novel therapies for this disease to augment anti-HIV immunity. T cell therapy is appealing in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089f82bad1b3d3520819d82f4a01fddd
https://europepmc.org/articles/PMC4445615/
https://europepmc.org/articles/PMC4445615/
Autor:
Ann M. Leen, Martha P. Mims, Cliona M. Rooney, Jun Ando, Helen E. Heslop, Minhtran C. Ngo, Juan F. Vera, Amelia Min-Venditti, Catherine M. Bollard, Stephen Gottschalk, Natalia Lapteva, Sravya Ennamuri
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 37(4)
Antigen-specific T cells provide a therapy for cancer that is highly specific, self-replicating, and potentially devoid of toxicity. Ideally, tumor-specific T cells should recognize multiple epitopes on multiple antigens to prevent tumor immune escap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c6b90855d2b6cba0559777ad6316e1
https://pubmed.ncbi.nlm.nih.gov/24714353
https://pubmed.ncbi.nlm.nih.gov/24714353
Adoptive immunotherapy is an appealing approach to cancer treatment, with the potential for more precise targeting and reduced toxicity. While early clinical trial data using adoptive T cells against post-transplant virus-associated hematologic malig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01787b58f6a2ee52202aac4629dc9b14
https://europepmc.org/articles/PMC3095061/
https://europepmc.org/articles/PMC3095061/
Publikováno v:
Development (Cambridge, England). 134(11)
In the developing ventral midbrain, the signaling molecule sonic hedgehog(SHH) is sufficient to specify a striped pattern of cell fates (midbrain arcs). Here, we asked whether and precisely how hedgehog (HH) signaling might be necessary for ventral m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f7581362771fb8f252ce80f35d3687
https://pubmed.ncbi.nlm.nih.gov/17507412
https://pubmed.ncbi.nlm.nih.gov/17507412