Výsledky vyhledávání - "Minh-Bao Huynh"

Akademický článek

Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)

The order of DNA methylation and histone modifications during transcription remained unclear. Here the authors show that HMGA2 induces DNA nicks at TGFB1-responsive genes, promoting nucleosome incorporation containing γ-H2AX, which is required for r

Externí odkaz: https://doaj.org/article/c551a764a6c040d58f3cbdc0affd583b

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Akademický článek

Glycosaminoglycans from Alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau.

Autor: Minh Bao Huynh, Mohand Ouidir Ouidja, Sandrine Chantepie, Gilles Carpentier, Auriane Maïza, Ganlin Zhang, Joao Vilares, Rita Raisman-Vozari, Dulce Papy-Garcia

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0209573 (2019)

Glycosaminoglycans (GAGs), including heparan sulfates and chondroitin sulfates, are major components of the extracellular matrix. Upon interacting with heparin binding growth factors (HBGF), GAGs participate to the maintaintenance of tissue homeostas

Externí odkaz: https://doaj.org/article/caf004795b6246f69dc0bc6e3efa8600

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Variability in proteoglycan biosynthetic genes reveals new facets of heparan sulfates diversity. A systematic review and analysis

Autor: Mohand Ouidir Ouidja, Denis S.F. Biard, Sandrine Chantepie, Xavier Laffray, Gael Le Douaron, Minh-Bao Huynh, Nicolas Rebergue, Auriane Maïza, Karla Rubio, Oscar González-Velasco, Guillermo Barreto, Javier De Las Rivas, Dulce Papy-Garcia

Publikováno v: medRxiv
MedRxiv pre

Proteoglycans are complex macromolecules formed of glycosaminoglycan chains covalently linked to core proteins through a linker tetrasaccharide common to heparan sulfate proteoglycans (HSPG) and chondroitin sulfate proteoglycans (CSPG). Biosynthesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c99100d1954d5b08f6261b137219903
https://hal.science/hal-03873029

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Glycosaminoglycans from Alzheimer’s disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau

Autor: Rita Raisman-Vozari, Joao Vilares, Gilles Carpentier, Mohand Ouidir Ouidja, Dulce Papy-Garcia, Auriane Maïza, Sandrine Chantepie, Ganlin Zhang, Minh Bao Huynh

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2019, 14 (1), pp.e0209573. ⟨10.1371/journal.pone.0209573⟩
PLOS ONE
PLoS ONE, Vol 14, Iss 1, p e0209573 (2019)

International audience; Glycosaminoglycans (GAGs), including heparan sulfates and chondroitin sulfates, are major components of the extracellular matrix. Upon interacting with heparin binding growth factors (HBGF), GAGs participate to the maintainten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4702a5ed4d5bdaa46e022c8d6827831
https://hal.sorbonne-universite.fr/hal-01983707

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The role of heparan sulfates in protein aggregation and their potential impact on neurodegeneration

Autor: Cecilia Vera, Auriane Maïza, Olivier Stettler, Sandrine Chantepie, Minh Bao Huynh, Mohand Ouidir Ouidja, Dulce Papy-Garcia, Alexandre Fifre

Publikováno v: FEBS Letters

Neurodegenerative disorders, such as Alzheimer´s, Parkinson´s, and prion diseases, are directly linked to the formation and accumulation of protein aggregates in the brain. These aggregates, principally made of proteins or peptides that clamp toget

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6beb5dbc9fa4f52bdda013c24bdb3b6e
Wiley Online Library

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HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology

Autor: Minh Bao Huynh, Joao Villares, Nadia Soussi-Yanicostas, Rita Raisman-Vozari, Ayikoe Guy Mensah-Nyagan, Julia E. Sepulveda-Diaz, Sandrine Chantepie, Seyedeh Maryam Alavi Naini, Toin H. van Kuppevelt, Dulce Papy-Garcia, Constantin Yanicostas, Estelle Jospin, Foudil Lamari, Mohand Ouidir Ouidja

Publikováno v: Brain, 138, 1339-54
Brain, 138, Pt 5, pp. 1339-54

Item does not contain fulltext Heparan sulphate (glucosamine) 3-O-sulphotransferase 2 (HS3ST2, also known as 3OST2) is an enzyme predominantly expressed in neurons wherein it generates rare 3-O-sulphated domains of unknown functions in heparan sulpha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bb16fd5087a7e14c685ad639b7f0c5
https://doi.org/10.1093/brain/awv056

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Akademický článek

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Glycosaminoglycans mimetics potentiate the clonogenicity, proliferation, migration and differentiation properties of rat mesenchymal stem cells

Autor: Thibault Bouderlique, Patricia Albanese, Guilhem Frescaline, Minh Bao Huynh, José Courty, Dulce Papy-Garcia

Publikováno v: Stem Cell Research, 8, 2, pp. 180-92
Stem Cell Research, 8, 180-92

Contains fulltext : 108052.pdf (Publisher’s version ) (Open Access) Successful use of stem cell-based therapeutic products is conditioned by transplantation of optimized cells in permissive microenvironment. Mesenchymal stem cell (MSC) fates are ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf9aa65ce7c11ed99f1e82df3a60d2b
https://doi.org/10.1016/j.scr.2011.09.005

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Alterations of overused supraspinatus tendon: A possible role of glycosaminoglycans and HARP/pleiotrophin in early tendon pathology

Autor: Mohamed F. Attia, Arlette Duchesnay, Gilles Carpentier, Isabelle Martelly, Camille Gossard, Marie-Claude Tassoni, Toin H. van Kuppevelt, Alex Scott, Louis J. Soslowsky, Minh Bao Huynh, José Courty

Publikováno v: Journal of Orthopaedic Research, 30, 1, pp. 61-71
Journal of Orthopaedic Research, 30, 61-71

Item does not contain fulltext Supraspinatus tendon overuse injuries lead to significant pain and disability in athletes and workers. Despite the prevalence and high social cost of these injuries, the early pathological events are not well known. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b62438dda7c10809d86667fcc074494
https://doi.org/10.1002/jor.21479

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