Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Mingzhe Ma"'
Autor:
Hui Yang, Qingqing Li, Xingxing Chen, Mingzhe Weng, Yakai Huang, Qiwen Chen, Xiaocen Liu, Haoyu Huang, Yanhuizhi Feng, Hanyu Zhou, Mengying Zhang, Weiya Pei, Xueqin Li, Qingsheng Fu, Liangyu Zhu, Yingying Wang, Xiang Kong, Kun Lv, Yan Zhang, Yangbai Sun, Mingzhe Ma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Therapeutic resistance represents a bottleneck to treatment in advanced gastric cancer (GC). Ferroptosis is an iron-dependent form of non-apoptotic cell death and is associated with anti-cancer therapeutic efficacy. Further investigations ar
Externí odkaz:
https://doaj.org/article/5b47e72cc9714a1994b452c776f6dfa4
Publikováno v:
Advanced Science, Vol 11, Iss 8, Pp n/a-n/a (2024)
Abstract As a vital project of forward chemical genetic research, target deconvolution aims to identify the molecular targets of an active hit compound. Chemoproteomics, either with chemical probe‐facilitated target enrichment or probe‐free, prov
Externí odkaz:
https://doaj.org/article/015c8b46d4ed4e2da0cb363bd16880c6
Autor:
Lisheng Fu, Xiaoyan Wang, Ying Yang, MeiHua Chen, Adilijiang Kuerban, Haojie Liu, Yiwei Dong, QianQian Cai, Mingzhe Ma, XingZhong Wu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-15 (2023)
Abstract Septins as GTPases in the cytoskeleton, are linked to a broad spectrum of cellular functions, including cell migration and the progression of hepatocellular carcinoma (HCC). However, roles of SEPT11, the new member of septin, have been hardl
Externí odkaz:
https://doaj.org/article/51989dd10c4f44389dee9c1f29ca5996
Autor:
Hui Yang, Yiren Hu, Mingzhe Weng, Xiaocen Liu, Ping Wan, Ye Hu, Mingzhe Ma, Yan Zhang, Hongping Xia, Kun Lv
Publikováno v:
Journal of Advanced Research, Vol 37, Iss , Pp 91-106 (2022)
Introduction: Tumors are usually refractory to anti-cancer therapeutics under hypoxic conditions. However, the underlying molecular mechanism remains to be elucidated. Objectives: Our study intended to identify hypoxia inducible lncRNAs and their bio
Externí odkaz:
https://doaj.org/article/cd6a8a2ba8924cc68a2a8884091d1f46
Autor:
Yali Wang, Ruting Xu, Mingzhe Ma, Kang Sun, Jianchun Jiang, Hao Sun, Shicai Liu, Yanren Jin, Ting Zhao
Publikováno v:
Materials, Vol 16, Iss 15, p 5236 (2023)
The effective utilization of charcoal and tar byproducts is a challenge for pyrolysis gasification of bamboo. Herein, the bamboo tar was modified via polymerization and acted as a new adhesive for the preparation of excellent bamboo-charcoal-derived
Externí odkaz:
https://doaj.org/article/762a2f4ab8514370a2b18a0b20766568
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104952- (2022)
Summary: GINS1 is a GINS complex subunit that functions along with the MCM2-7 complex and Cdc45 in eukaryotic DNA replication. Despite the significance of the GINS complex in the switch between quiescence and proliferation of glioma cells inside and
Externí odkaz:
https://doaj.org/article/819bb96c4f1d447ab4993ee1b12a020a
Autor:
Ruiyao Chen, Yulu Miao, Xuan Hao, Bei Gao, Mingzhe Ma, John Z.H. Zhang, Rui Wang, Sha Li, Xiao He, Lujia Zhang
Publikováno v:
Food Science & Nutrition, Vol 9, Iss 6, Pp 2943-2953 (2021)
Abstract Food‐derived angiotensin I‐converting enzyme (ACE) inhibitory peptides represent a potential source of new antihypertensive. However, their characteristics and binding mechanisms were not well understood. In this study, novel energy calc
Externí odkaz:
https://doaj.org/article/b008f798f51e4f4bac64381f36f96a28
Autor:
Mingzhe Ma, Yinghui Feng, Yulu Miao, Qiang Shen, Shuting Tang, Juan Dong, John Z. H. Zhang, Lujia Zhang
Publikováno v:
Foods, Vol 12, Iss 8, p 1573 (2023)
Chronic diseases, such as hypertension, cause great harm to human health. Conventional drugs have promising therapeutic effects, but also cause significant side effects. Food-sourced angiotensin-converting enzyme (ACE) inhibitory peptides are an exce
Externí odkaz:
https://doaj.org/article/47c8383a84f5457b82dbf9e185753dc5
Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
Autor:
Tiantian Wei, Jue Wang, Ruqi Liang, Wendong Chen, Yilan Chen, Mingzhe Ma, An He, Yifei Du, Wenjing Zhou, Zhiying Zhang, Xin Zeng, Chu Wang, Jin Lu, Xing Guo, Xiao-Wei Chen, Youjun Wang, Ruijun Tian, Junyu Xiao, Xiaoguang Lei
Publikováno v:
eLife, Vol 11 (2022)
The dual-specificity tyrosine phosphorylation-regulated kinase DYRK2 has emerged as a critical regulator of cellular processes. We took a chemical biology approach to gain further insights into its function. We developed C17, a potent small-molecule
Externí odkaz:
https://doaj.org/article/d371ca8cabea45129010611a2413de8e
Autor:
Hui Yang, Xiaocen Liu, Xiaolong Zhu, Xueqin Li, Lan Jiang, Min Zhong, Mengying Zhang, Tianbing Chen, Mingzhe Ma, Xiuming Liang, Kun Lv
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
CPVL (carboxypeptidase, vitellogenic-like) is a serine carboxypeptidase that was first characterized in human macrophages. However, the function of CPVL remains unclear in a variety of tumors. The quantitative PCR (qPCR), Western blotting, and IHC as
Externí odkaz:
https://doaj.org/article/79f67ce47a354e2ba31d39d16b9858b0