Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mingyun Bae"'
Autor:
Mingyun Bae, Gyuhee Kim, Tae-Rim Lee, Jin Mo Ahn, Hyunwook Park, Sook Ryun Park, Ki Byung Song, Eunsung Jun, Dongryul Oh, Jeong-Won Lee, Young Sik Park, Ki-Won Song, Jeong-Sik Byeon, Bo Hyun Kim, Joo Hyuk Sohn, Min Hwan Kim, Gun Min Kim, Eui Kyu Chie, Hyun-Cheol Kang, Sun-Young Kong, Sang Myung Woo, Jeong Eon Lee, Jai Min Ryu, Junnam Lee, Dasom Kim, Chang-Seok Ki, Eun-Hae Cho, Jung Kyoon Choi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Multi-cancer early detection remains a key challenge in cell-free DNA (cfDNA)-based liquid biopsy. Here, we perform cfDNA whole-genome sequencing to generate two test datasets covering 2125 patient samples of 9 cancer types and 1241 normal c
Externí odkaz:
https://doaj.org/article/df10ed343d5c4d9d913691c7935c3617
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-11 (2017)
Abstract Background Most DNA cancer methylation markers are based on the transcriptional regulation of the promoter-gene relationship. Recently, the importance of long-range interactions between distal CpGs and target genes has been revealed. Here, w
Externí odkaz:
https://doaj.org/article/5fade54c47b1431a9a216504d8a08c5f
Autor:
Seong-Min Park, Eun-Young Choi, Mingyun Bae, Sunshin Kim, Jong Bae Park, Heon Yoo, Jung Kyoon Choi, Youn-Jae Kim, Seung-Hoon Lee, In-Hoo Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migratio
Externí odkaz:
https://doaj.org/article/07788f10331948db8924a111c4c9b877
Autor:
Jung Kyoon Choi, Woojin Yang, Seong-Min Park, Kiwon Jang, Youn-Jae Kim, Kwoneel Kim, Eun Young Choi, Mingyun Bae
Publikováno v:
Nature Genetics. 48:1321-1326
Recurrence is a hallmark of cancer-driving mutations. Recurrent mutations can arise at the same site or affect the same gene at different sites. Here we identified a set of mutations arising in individual samples and altering different cis-regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369f0b41528930f69448bd609ddddccd
https://doi.org/10.1038/ng.3682
https://doi.org/10.1038/ng.3682
Estimation of HOXA9 and HOXA10 expression as diagnostic and prognostic markers for breast cancer. Figure S2. Validation of chromatin interaction between HOXA9 and HOXA10 promoters using 3C PCR in MDA-MB-231 breast cancer cells and MCF10A normal breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9917642488aedb6bded5b96965dbaee1
Publikováno v:
CLINICAL EPIGENETICS(9)
Clinical Epigenetics
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-11 (2017)
Clinical Epigenetics
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-11 (2017)
Background Most DNA cancer methylation markers are based on the transcriptional regulation of the promoter-gene relationship. Recently, the importance of long-range interactions between distal CpGs and target genes has been revealed. Here, we attempt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d29f15fe45d268c86aba162b680cbd
http://open-repository.kisti.re.kr/cube/handle/open_repository/473695.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/473695.do
Autor:
Jong Bae Park, Jung Kyoon Choi, Youn-Jae Kim, In-Hoo Kim, Eun Young Choi, Sunshin Kim, Mingyun Bae, Heon Yoo, Seongmin Park, Seunghoon Lee
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS(7)
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
NATURE COMMUNICATIONS(7)
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Although several somatic single nucleotide variations in histone H3.3 have been investigated as cancer drivers, other types of aberration have not been well studied. Here, we demonstrate that overexpression of H3F3A, encoding H3.3, is associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c36078be50652bfa97bd9fc4e5b35b
http://europepmc.org/articles/PMC5477500
http://europepmc.org/articles/PMC5477500