Zobrazeno 1 - 10
of 484
pro vyhledávání: '"Mingyao, Li"'
Publikováno v:
JACS Au, Vol 4, Iss 4, Pp 1278-1294 (2024)
Externí odkaz:
https://doaj.org/article/25fd4748ff634a1195c9f9e999adfbf4
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-33 (2023)
Abstract Background Single-cell RNA-sequencing (scRNA-seq) measures gene expression in single cells, while single-nucleus ATAC-sequencing (snATAC-seq) quantifies chromatin accessibility in single nuclei. These two data types provide complementary inf
Externí odkaz:
https://doaj.org/article/1e95f251a8334545ae46627e26715605
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Astrocytes are one of the brain’s major cell types and are responsible for maintaining neuronal homeostasis via regulating the extracellular environment, providing metabolic support, and modulating synaptic activity. In neurodegenerative d
Externí odkaz:
https://doaj.org/article/6b96018bd86244ba85ad40663b4ec31f
Leveraging spatial transcriptomics data to recover cell locations in single-cell RNA-seq with CeLEry
Autor:
Qihuang Zhang, Shunzhou Jiang, Amelia Schroeder, Jian Hu, Kejie Li, Baohong Zhang, David Dai, Edward B. Lee, Rui Xiao, Mingyao Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular heterogeneity in health and disease. However, the lack of physical relationships among dissociated cells has limited its applications. To address this is
Externí odkaz:
https://doaj.org/article/211cff1dc45b4b52ab015e67533383d8
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
SpaDecon is a semi-supervised learning-based method for cell-type deconvolution of spatially resolved transcriptomics (SRT) data that is also computationally fast and memory efficient for large-scale SRT studies.
Externí odkaz:
https://doaj.org/article/89c1ca5951c34a6f80c7a259d6bbc7e5
Autor:
Tina Glisovic-Aplenc, Jen Liddle, Lusha Cao, Kevin Nestler, Han Fisher, Asif Chinwalla, Hossein Fazelinia, Saar Gill, Yi Xing, Mingyao LI, Kathrin Bernt, Jeremy Balsbaugh, Richard Aplenc
Publikováno v:
HemaSphere, Vol 7, p e37582f2 (2023)
Externí odkaz:
https://doaj.org/article/7892aea25dee4b03828bae681e063105
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Previous efforts to study the circadian clock using scRNA-seq have relied on time course designs that treat cell collection time as a proxy for circadian time. Here, the authors introduce a statistical method to infer circadian timing directly from e
Externí odkaz:
https://doaj.org/article/98eebcf6b82b4aa5b880e252927e3e37
Autor:
Treefa Shwani, Charles Zhang, Leah A. Owen, Akbar Shakoor, Albert T. Vitale, John H. Lillvis, Julie L. Barr, Parker Cromwell, Robert Finley, Nadine Husami, Elizabeth Au, Rylee A. Zavala, Elijah C. Graves, Sarah X. Zhang, Michael H. Farkas, David A. Ammar, Karen M. Allison, Amany Tawfik, Richard M. Sherva, Mingyao Li, Dwight Stambolian, Ivana K. Kim, Lindsay A. Farrer, Margaret M. DeAngelis
Publikováno v:
Cells, Vol 12, Iss 23, p 2668 (2023)
Age-related macular degeneration (AMD) is a leading cause of blindness, and elucidating its underlying disease mechanisms is vital to the development of appropriate therapeutics. We identified differentially expressed genes (DEGs) and differentially
Externí odkaz:
https://doaj.org/article/e8beab75624a4f28ace7d19d17448129
Autor:
Jiarong Li, Hua Zhang, Hui Ouyang, Weixin Xu, Yong Sun, Youbao Zhong, Lifang Wang, Jiaxing Huang, Junchang Chen, Mingyao Li, Weifeng Zhu, Yuhui Liu, Ronghua Liu
Publikováno v:
Molecules, Vol 28, Iss 22, p 7471 (2023)
Type 2 diabetes mellitus (T2DM) is an increasingly prevalent and serious health problem. Its onset is typically associated with metabolic disorders and disturbances in the gut microbiota. Previous studies have reported the anti-T2DM effects of Puerar
Externí odkaz:
https://doaj.org/article/c88f431278364cae88bb61d63f3c5777
Autor:
Fengling Hu, Andrew A. Chen, Hannah Horng, Vishnu Bashyam, Christos Davatzikos, Aaron Alexander-Bloch, Mingyao Li, Haochang Shou, Theodore D. Satterthwaite, Meichen Yu, Russell T. Shinohara
Publikováno v:
NeuroImage, Vol 274, Iss , Pp 120125- (2023)
Magnetic resonance imaging and computed tomography from multiple batches (e.g. sites, scanners, datasets, etc.) are increasingly used alongside complex downstream analyses to obtain new insights into the human brain. However, significant confounding
Externí odkaz:
https://doaj.org/article/6dec96d34ba34395b20d9e3d639003fa